Effects of the analgesic agent tramadol in normal and arthritic rats: comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine

Human Pharmacology and Abuse Potential of the Analgesic Buprenorphine

1978 • 787 citations

Proceedings of the Vth World Congress on Pain

1988 • 349 citations

Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids.

1988 • 296 citations

In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia.

1988 • 292 citations

Nalbuphine

1985 • 196 citations

Ethical standards for investigations of experimental pain in animals

1980 • 166 citations

The analgesic effects of morphine, but not those of the enkephalinase inhibitor thiorphan, are enhanced in arthritic rats

1983 • 155 citations

A new method for the evaluation of analgesic activity using adjuvant-induced arthritis in the rat

1975 • 150 citations

Met-enkephalin levels and opiate receptors in the spinal cord of chronic suffering rats

1980 • 131 citations

Reaction thresholds to pressure in edematous hindpaws of rats and responses to analgesic drugs.

1965 • 126 citations

Prodynorphin gene expression is enhanced in the spinal cord of chronic arthritic rats

1987 • 122 citations

Evaluation of nalbuphine for abuse potential

1972 • 109 citations

Nalbuphine: an autoradiographic opioid receptor binding profile in the central nervous system of an agonist/antagonist analgesic.

1988 • 107 citations

A comparison of the analgesic effect of intramuscular nalbuphine and morphine in patients with postoperative pain.

1978 • 101 citations

Potent antinociceptive effects of Kelatorphan (a highly efficient inhibitor of multiple enkephalin-degrading enzymes) systemically administered in normal and arthritic rats

1989 • 100 citations

Afferent fibers mediate the increase of met-enkephalin elicited in rat spinal cord by localized pain

1984 • 99 citations

Differential effects of various doses of morphine and naloxone on two nociceptive test thresholds in arthritic and normal rats

1990 • 92 citations

Opioid receptor types and antinociceptive activity in chronic inflammation: bothe κ- and μ-opiate agonistic effects are enhanced in arthritic rats

1986 • 72 citations

Use of Freund's adjuvant arthritis test in anti-flammatory drug screening in the rat: value of animal selection and preparation at the breeding center.

1976 • 72 citations

Effects of tramadol on motor and sensory responses of the spinal nociceptive system in the rat

1987 • 57 citations

Itrathecal injection of codeine, buprenorphine, tildine, tramadol, and nefopam depresses the tail-flick response in rats

1986 • 53 citations

Human pharmacology of narcotic antagonists.

1979 • 52 citations

The effect of Freund's adjuvants on blood-cerebrospinal fluid barrier permeability

1984 • 47 citations

Co-localization of proenkephalin- and prodynorphin-derived opioid peptides in laminae IV/V spinal neurons revealed in arthritic rats

1988 • 42 citations

Chapter 21 Paradoxical effects of low doses of naloxone in experimental models of inflammatory pain

1988 • 42 citations

Repeated low doses of morphine induce a rapid tolerance in arthritic rats but a potentiation of opiate analgesia in normal animals

1986 • 31 citations

Long-term administration of the centrally acting analgesic tramadol did not induce dependence or tolerance

1987 • 23 citations

Functional Response of Multiple Opioid Systems to Chronic Arthritic Pain in the Rat^a

1986 • 20 citations

[A doubleblind comparison of tramadol and buprenorphine in the control of postoperative pain (author's transl)].

1981 • 14 citations

Deleted Work

1955 • 0 citations