Assembly of phage Mu transpososomes: Cooperative transitions assisted by protein and DNA scaffolds

Crystal Structure of the Catalytic Domain of HIV-1 Integrase: Similarity to Other Polynucleotidyl Transferases

1994 • 804 citations

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

1991 • 566 citations

Structure of Ribonuclease H Phased at 2 Å Resolution by MAD Analysis of the Selenomethionyl Protein

1990 • 475 citations

TRANSPOSITIONAL RECOMBINATION: Mechanistic Insights from Studies of Mu and Other Elements

1992 • 393 citations

Three-dimensional structure of ribonuclease H from E. coli

1990 • 348 citations

Atomic structure of the RuvC resolvase: A holliday junction-specific endonuclease from E. coli

1994 • 284 citations

Transpososomes: Stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA

1987 • 231 citations

Structure of the bacteriophage Mu transposase core: A common structural motif for DNA transposition and retroviral integration

1995 • 225 citations

Site-specific recognition of the bacteriophage mu ends by the mu a protein

1984 • 207 citations

Tn7 transposition: Target DNA recognition is mediated by multiple Tn7-encoded proteins in a purified in vitro system

1993 • 189 citations

Structural aspects of a higher order nucleoprotein complex: induction of an altered DNA structure at the Mu-host junction of the Mu type 1 transpososome.

1991 • 177 citations

Transposition of Mu DNA: Joining of Mu to target DNA can be uncoupled from cleavage at the ends of Mu

1987 • 172 citations

The phage Mu transpososome core: DNA requirements for assembly and function.

1995 • 171 citations

Assembly of the active form of the transposase-Mu DNA complex: A critical control point in Mu transposition

1992 • 161 citations

Efficient Mu transposition requires interaction of transposase with a DNA sequence at the Mu operator: Implications for regulation

1989 • 161 citations

Tn7 transposition in vitro proceeds through an excised transposon intermediate generated by staggered breaks in DNA

1991 • 159 citations

The Hin Invertasome: Protein-Mediated Joining of Distant Recombination Sites at the Enhancer

1990 • 158 citations

Polynucleotidyl transfer reactions in transpositional DNA recombination.

1992 • 154 citations

Interaction of distinct domains in Mu transposase with Mu DNA ends and an internal transpositional enhancer

1989 • 151 citations

Target immunity of Mu transposition reflects a differential distribution of Mu B protein

1988 • 141 citations

Identification of residues in the Mu transposase essential for catalysis.

1994 • 139 citations

Complete transposition requires four active monomers in the mu transposase tetramer.

1994 • 125 citations

B protein of bacteriophage mu is an ATPase that preferentially stimulates intermolecular DNA strand transfer.

1987 • 122 citations

DNA-promoted assembly of the active tetramer of the Mu transposase.

1992 • 122 citations

Site-specific HU binding in the Mu transpososome: conversion of a sequence-independent DNA-binding protein into a chemical nuclease.

1993 • 111 citations

A protein factor which reduces the negative supercoiling requirement in the Mu DNA strand transfer reaction is Escherichia coli integration host factor

1989 • 110 citations

MuB protein allosterically activates strand transfer by the transposase of phage Mu

1991 • 110 citations

Division of labor among monomers within the Mu transposase tetramer

1993 • 108 citations

Action at a distance in Mu DNA transposition: an enhancer-like element is the site of action of supercoiling relief activity by integration host factor (IHF).

1989 • 97 citations

Structural domains in phage Mu transposase: identification of the site-specific DNA-binding domain.

1987 • 88 citations

Amplification and purification of the bacteriophage Mu encoded B transposition protein.

1985 • 86 citations

The Mu transpositional enhancer can function in trans: Requirement of the enhancer for synapsis but not strand cleavage

1992 • 79 citations

Intermediates in Hin-mediated DNA inversion: a role for Fis and the recombinational enhancer in the strand exchange reaction.

1989 • 76 citations

DNase protection analysis of the stable synaptic complexes involved in Mu transposition.

1991 • 75 citations

A novel class of winged helix–turn–helix protein: the DNA–binding domain of Mu transposase

1994 • 74 citations

Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro transposition characteristics of mini-Mu plasmids carrying terminal base pair mutations.

1991 • 72 citations

Step-arrest Mutants of Phage Mu Transposase

1995 • 67 citations

A domain sharing model for active site assembly within the Mu A tetramer during transposition: the enhancer may specify domain contributions.

1995 • 52 citations

A second high affinity HU binding site in the phage Mu transpososome.

1994 • 51 citations

Transposase contacts with mu DNA ends.

1991 • 49 citations

Steady-state kinetic analysis of ATP hydrolysis by the B protein of bacteriophage mu. Involvement of protein oligomerization in the ATPase cycle.

1991 • 47 citations

Role of the A protein-binding sites in the in vitro transposition of mu DNA. A complex circuit of interactions involving the mu ends and the transpositional enhancer.

1992 • 46 citations

Two mutations of phage Mu transposase that affect strand transfer or interactions with B protein lie in distinct polypeptide domains

1991 • 44 citations

Mechanistic aspects of DNA transposition

1992 • 43 citations

Characterization of a region in phage Mu transposase that is involved in interaction with the Mu B protein.

1994 • 39 citations

Flanking host sequences can exert an inhibitory effect on the cleavage step of the in vitro mu DNA strand transfer reaction.

1992 • 37 citations

DNA sequence of the control region of phage D108: the N-terminal amino acid sequences of repressor and transposase are similar both in phage D108 and in its relative, phage Mu

1986 • 35 citations

Characterization of the lysogenic repressor(c)from transposable Mu-like bacteriophage D108

1991 • 6 citations