Cooperative interactions of protein kinase C and cAMP‐dependent protein kinase systems in human promyelocytic leukemia HL60 cells

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

1977 • 2,134 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

1985 • 736 citations

Protein phosphorylation in the brain

1983 • 428 citations

Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes

1987 • 321 citations

Cyclic Nucleotide-induced Maturation of Human Promyelocytic Leukemia Cells

1982 • 213 citations

Polyclonal antibodies to phospholipid/Ca2+-dependent protein kinase and immunocytochemical localization of the enzyme in rat brain.

1985 • 193 citations

Immunocytochemical localization of protein kinase C in identified neuronal compartments of rat brain

1986 • 129 citations

Protein kinase C in fibroblasts. Characteristics of its intracellular location during growth and after exposure to phorbol esters and other mitogens.

1987 • 127 citations

Immunocytochemical evidence for phorbol ester-induced protein kinase C translocation in HL60 cells

1986 • 90 citations

Control of HL-60 cell differentiation lineage specificity, a late event occurring after precommitment.

1987 • 82 citations

Protein kinase C interferes with N_i‐mediated inhibition of human platelet adenylate cyclase

1985 • 68 citations

Activation of adipocyte adenylate cyclase by protein kinase C.

1986 • 68 citations

The protein kinase C activator phorbol‐12‐myristate‐13‐acetate enhances cyclic AMP accumulation in pheochromocytoma cells

1986 • 54 citations

Modulation of the maturation of human leukemic promyelocytes (HL-60) to granulocytes or macrophages

1982 • 50 citations

Comparative effects of polymyxin B, phorbol ester and bryostatin on protein phosphorylation, protein kinase C translocation, phospholipid metabolism and differentiation of HL60 cells

1987 • 49 citations

Immunocytochemical evidence for phorbol ester-induced directional translocations of protein kinase C in HL60, K562, CHO, and E7SKS cells: possible role in differentiation.

1987 • 42 citations

Regulation of protein kinase C by cyclic adenosine 3':5'-monophosphate and a tumor promoter in skeletal myoblasts.

1987 • 40 citations

Differential effects of various protein kinase C activators on protein phosphorylation in human acute myeloblastic leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.

1987 • 40 citations

Phorbol Esters Increase GTP‐Dependent Adenylate Cyclase Activity in Rat Brain Striatal Membranes

1986 • 39 citations

Effects of phorbol ester on translocation and down-regulation of protein kinase C and phosphorylation of endogenous proteins in human acute myeloid leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.

1987 • 37 citations

Activation of protein kinase C inhibits prostaglandin- and potentiates adenosine receptor-stimulated accumulation of cyclic AMP in a human T-cell leukemia line

1987 • 29 citations

Prostaglandin E1 and forskolin antagonize C-kinase activation in the human platelet

1987 • 26 citations

Phorbol ester inhibits phosphatidylserine synthesis in human promyelocytic leukaemia HL60 cells. Possible involvement of free radicals and correlation with phosphorylation of nuclear protein 1b

1987 • 25 citations

Interactions between cyclic AMP‐ and phorbol ester‐dependent phosphorylation systems in S49 mouse lymphoma cells

1985 • 25 citations

Differential effects of tumor promoters on cAMP production: Inhibition of receptor-mediated and potentiation of cholera toxin-mediated stimulation

1985 • 23 citations

Immunocytochemical localization of protein kinase C in resting and activated human neutrophils

1987 • 21 citations

Phorbol ester-mediated protein phosphorylations in S49 mouse lymphoma cells.

1985 • 20 citations

Potentiation of prostaglandin E1-stimulated cAMP formation by 12-O-tetradecanoylphorbol-13-acetate in balb/C mouse 3T3 cells

1986 • 12 citations

Differential effects of phorbol ester on the β-adrenergic response of normal and ras-transformed NIH3T3 cells

1985 • 10 citations

Cyclic AMP stimulates dephosphorylation of specific proteins in intact S49 mouse lymphoma cells

1985 • 9 citations