Minimal residual disease (MRD) measurement as a tool to compare the efficacy of chemotherapeutic drug regimens using Escherichia Coli‐asparaginase or Erwinia‐asparaginase in childhood acute lymphoblastic leukemia (ALL)
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References (27)
Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood
1998 • 968 citations
Clinical Significance of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia
1998 • 772 citations
Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group.
2000 • 634 citations
Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital
2004 • 466 citations
Clinical importance of minimal residual disease in childhood acute lymphoblastic leukemia
2000 • 462 citations
Evidence that the L-Asparaginase Activity of Guinea Pig Serum is responsible for its Antilymphoma Effects
1961 • 460 citations
Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer---Children's Leukemia Group phase 3 trial
2002 • 409 citations
Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets Report of the BIOMED-1 CONCERTED ACTION: Investigation of minimal residual disease in acute leukemia
1999 • 356 citations
Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes
1998 • 339 citations
Comparative pharmacokinetic studies of three asparaginase preparations.
1993 • 328 citations
Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983–1995
2000 • 322 citations
Toxicity of E. coli L-asparaginase in man
1970 • 290 citations
Childhood acute lymphoblastic leukaemia – current status and future perspectives
2001 • 266 citations
Pharmacokinetic/Pharmacodynamic Relationships of Asparaginase Formulations
2005 • 225 citations
Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations
1997 • 217 citations
Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations
1996 • 210 citations
Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia
2000 • 203 citations
Long-term results of three randomized trials (58831, 58832, 58881) in childhood acute lymphoblastic leukemia: a CLCG-EORTC report
2000 • 200 citations
Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR
2002 • 125 citations
Evaluation of immunologic crossreaction of antiasparaginase antibodies in acute lymphoblastic leukemia (ALL) and lymphoma patients
2003 • 122 citations
L-asparagine depletion and L-asparaginase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C. or E. coli L-asparaginase as first exposure
2000 • 106 citations
Precursor-B-ALL with DH–JH gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14
2001 • 97 citations
Non‐randomised study comparing toxicity of escherichia coli and erwinia asparaginase in children with leukaemia
1990 • 84 citations
Prognostic Significance of Early Response to a Single Dose of Asparaginase in Childhood Acute Lymphoblastic Leukemia
1999 • 62 citations
Comparison of intramuscular therapy with Erwinia asparaginase and asparaginase Medac: pharmacokinetics, pharmacodynamics, formation of antibodies and influence on the coagulation system
2001 • 58 citations
The best way to use asparaginase in childhood acute lymphatic leukaemia – still to be defined?
2004 • 51 citations
Clonal Analysis of B-Cell Leukemias and Lymphomas using the Polymerase Chain Reaction for the Third Complementarity Determining Region of the IgH Gene: A Study of 75 Cases from Nagasaki Japan
1999 • 9 citations