A hypothesis for the pathway of the thermally-induced unfolding of bovine pancreatic ribonuclease

Prediction of protein conformation

1974 • 3,327 citations

Conformational parameters for amino acids in helical, β-sheet, and random coil regions calculated from proteins

1974 • 2,173 citations

The Preparation of Subtilisin-modified Ribonuclease and the Separation of the Peptide and Protein Components

1959 • 632 citations

Tertiary Structure of Ribonuclease

1967 • 573 citations

The Sequence of Amino Acid Residues in Bovine Pancreatic Ribonuclease: Revisions and Confirmations

1963 • 562 citations

The Three-Dimensional Structure of Ribonuclease-S

1970 • 510 citations

The Nature of the Amino Acid Residues Involved in the Inactivation of Ribonuclease by Iodoacetate

1959 • 409 citations

Calculations of Conformations of Polypeptides

1968 • 387 citations

Helix-coil transition of the isolated amino terminus of ribonuclease

1971 • 310 citations

Reductive Cleavage of Disulfide Bridges in Ribonuclease

1957 • 278 citations

Structural Studies of Ribonuclease. V. Reversible Change of Configuration^1-3

1961 • 263 citations

The Reaction of Iodoacetate with Methionine

1959 • 242 citations

Analysis of Conformations of Amino Acid Residues and Prediction of Backbone Topography in Proteins

1974 • 236 citations

Theoretical and experimental studies of conformations of polypeptides

1971 • 219 citations

An Experimental Approach to the Study of the Folding of Staphylococcal Nuclease

1969 • 156 citations

Analysis of the code relating sequence to conformation in proteins: Possible implications for the mechanism of formation of helical regions

1971 • 154 citations

THE LIMITED DIGESTION OF RIBONUCLEASE WITH PEPSIN

1956 • 136 citations

Pathways of folding of reduced bovine pancreatic ribonuclease

1974 • 129 citations

Studies on the tryptic digestion of myosin

1959 • 114 citations

Atlas of molecular structures in biology

1973 • 109 citations

Simultaneous Formation of Two Alternative Enzymically Active Structures by Complementation of Two Overlapping Fragments of Staphylococcal Nuclease

1971 • 107 citations

Steps in the Formation of Active Derivatives of Staphylococcal Nuclease during Trypsin Digestion

1968 • 106 citations

Structural Studies of Ribonuclease. VII. Chymotryptic Hydrolysis of Ribonuclease A at Elevated Temperatures^*

1963 • 97 citations

Formation of Randomly Paired Disulfide Bonds in Des-(121–124)-ribonuclease after Reduction and Reoxidation

1970 • 93 citations

On the dominance of short-range interactions in polypeptides and proteins

1973 • 88 citations

Reactivation of des(119–124) Ribonuclease A by Mixture with Synthetic COOH-terminal Peptides; the Role of Phenylalanine-120

1972 • 86 citations

On the Non‐Essentiality of Two Specific Disulphide Bonds in Ribonuclease for its Biological Activity

1967 • 80 citations

Evidence for nucleation in the folding of reduced hen egg lysozyme

1973 • 69 citations

Reactivation of des(119-, 120-, or 121–124) Ribonuclease A by Mixture with Synthetic COOH-terminal Peptides of Varying Lengths

1972 • 67 citations

The Buried Tyrosyl Residues of Ribonuclease

1963 • 67 citations

The Effect of Dodecyl Sulfate on the Ultraviolet Spectra of Proteins^*

1962 • 66 citations

Ultraviolet Spectral Studies of Acid- and Base-denatured Ribonuclease

1961 • 63 citations

Structural Studies of Ribonuclease. XI. Kinetics of Denaturation

1963 • 63 citations

The Action of Trypsin on Ribonuclease-S^*

1962 • 62 citations

Structural Studies of Ribonuclease. VIII. Tryptic Hydrolysis of Ribonuclease A at Elevated Temperatures^*

1963 • 55 citations

Structural Studies of Ribonuclease. XXII. Location of the Third Buried Tyrosyl Residue in Ribonuclease^*

1966 • 50 citations

Structural Studies of Ribonuclease. XXIII. Pairing of the Tyrosyl and Carboxyl Groups^*

1966 • 48 citations

A synthetic 70-amino acid residue analog of ribonuclease S-protein with enzymic activity.

1975 • 48 citations

Immobilized carboxypeptidase A as a probe for studying the thermally induced unfolding of bovine pancreatic ribonuclease

1975 • 43 citations

Intermediate Stages in the Thermally Induced Transconformation Reactions of Bovine Pancreatic Ribonuclease A^*

1967 • 40 citations

The Buried Tyrosyl Residues of Ribonuclease

1963 • 37 citations

[Relation of the secondary structure of globular proteins to their primary structure].

1970 • 36 citations

Further Studies on the Alkylation of the Histidine Residues at the Active Site of Pancreatic Ribonuclease

1968 • 34 citations

PROTON FOURIER TRANSFORM NMR STUDIES OF THE UNFOLDING OF RIBONUCLEASE

1973 • 27 citations

Structural Studies of Ribonuclease. II. Deuterium Exchange Studies of Two Crystalline Forms of Ribonuclease^1,2

1960 • 25 citations

Denaturation of proteins. IV. N.M.R. studies of ribonuclease-A

1972 • 24 citations

The effect of temperature on the chemical shifts of the histidine residues of ribonuclease A

1972 • 23 citations

Atlas of molecular structures in biology, 1. ribonuclease-S

1976 • 17 citations

Structural Studies of Ribonuclease. XXVI. The Role of Tyrosine 115 in the Refolding of Ribonuclease^*

1966 • 17 citations

Structural Studies of Ribonuclease. XIII. Physicochemical Properties of Tryptic Modifications of Ribonuclease^*

1964 • 16 citations