Correlation between p53 gene expression and tumor‐cell proliferation in oropharyngeal cancer

p53 function and dysfunction

1992 • 1,918 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1992 • 1,358 citations

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

1992 • 1,117 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

1992 • 784 citations

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

1992 • 757 citations

Measurement of cell kinetics in human tumours in vivo using bromodeoxyuridine incorporation and flow cytometry

1988 • 310 citations

Frequent p53 mutations in head and neck cancer.

1992 • 287 citations

Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck

1991 • 259 citations

Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.

1992 • 237 citations

Expression of p53 in premalignant and malignant squamous epithelium.

1991 • 237 citations

Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.

1992 • 215 citations

Human tumour cell kinetics using a monoclonal antibody against iododeoxyuridine: Intratumour sampling variations

1988 • 104 citations

Overexpression of P53 in head and neck cancer

1992 • 91 citations

Cytogenetic Evidence of the Multistep Origin of Head and Neck Squamous Cell Carcinomas

1992 • 70 citations

Expression of p53 in human esophageal carcinoma: An immunohistochemical study with correlation to proliferating cell nuclear antigen expression

1992 • 64 citations

The rationale for continuous, hyperfractionated, accelerated radiotherapy (chart)

1990 • 62 citations

Manual of Clinical Oncology

1987 • 52 citations

In vivo measurement of the potential doubling time by flowcytometry in oropharyngeal cancer treated by conventional radiotherapy

1993 • 48 citations

Improved immunohistochemical detection of p53 protein in paraffin--embedded tissues reveals elevated levels in most head and neck and lung carcinomas: correlation with clinicopathological parameters.

1992 • 30 citations

Oncogenes and tumour suppressor genes in human cancers: clinical implications.

1992 • 3 citations

Extensive Calcification in a Case of Mesenchymoma

1951 • 2 citations