Frequent p53 mutations in head and neck cancer.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

1988 • 1,582 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

Genetic Mechanisms of Tumor Suppression by the Human p53 Gene

1990 • 540 citations

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.

1990 • 515 citations

Nuclear Accumulation of p53 Protein Is Mediated by Several Nuclear Localization Signals and Plays a Role in Tumorigenesis

1990 • 328 citations

p53 Mutations in non-small cell lung cancer in Japan: Association between mutations and smoking

1992 • 280 citations

p53 point mutation in HPV negative human cervical carcinoma cell lines.

1991 • 271 citations

HUMAN TUMOR SUPPRESSOR GENES

1990 • 266 citations

Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck

1991 • 259 citations

Genetic analysis of human esophageal tumors from two high incidence geographic areas: frequent p53 base substitutions and absence of ras mutations.

1991 • 196 citations

Growth suppression of human breast cancer cells by the introduction of a wild-type p53 gene.

1991 • 195 citations

Growth of Head and Neck Squamous Cell Carcinoma in Nude Mice: Potentiation of Laryngeal Carcinoma by 17beta-Estradiol

1988 • 32 citations