Retrovirus‐mediated transfer of the multidrug resistance gene into human haemopoietic progenitor cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

Hematopoietic Reconstitution in a Patient with Fanconi's Anemia by Means of Umbilical-Cord Blood from an HLA-Identical Sibling

1989 • 2,107 citations

Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells.

1989 • 1,220 citations

A safe packaging line for gene transfer: separating viral genes on two different plasmids

1988 • 1,118 citations

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1991 • 962 citations

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

1990 • 736 citations

Construction and use of a safe and efficient amphotropic packaging cell line

1988 • 637 citations

Mechanism of multidrug resistance

1988 • 630 citations

Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults.

1992 • 506 citations

Selection of Drug-Resistant Bone Marrow Cells in Vivo After Retroviral Transfer of Human MDR 1

1992 • 500 citations

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.

1988 • 489 citations

Construction and use of a safe and efficient amphotropic packaging cell line

1988 • 416 citations

Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistant phenotype [see comments]

1992 • 323 citations

Growth of human umbilical-cord blood in longterm haemopoietic cultures

1992 • 217 citations

Transfer and expression of the human multiple drug resistance gene into live mice.

1992 • 210 citations

Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance.

1991 • 152 citations

Transfer and expression of the human multiple drug resistance gene in human CD34+ cells

1994 • 137 citations

Human cord blood cells as targets for gene transfer: potential use in genetic therapies of severe combined immunodeficiency disease.

1993 • 122 citations

Mechanisms of Multidrug Resistance

1995 • 120 citations

Fibrinogen potentiates the effect of interleukin-3 on early human hematopoietic progenitors

1993 • 32 citations

Gene transfer by retrovirus-derived shuttle vectors in the generation of murine bispecific monoclonal antibodies.

1990 • 24 citations

Umbilical Cord Blood Banking: Evaluation of the Collection Procedure and of CFU-GM Content

1993 • 6 citations

Preparation of Samples for Flow Cytometric Analysis

1993 • 5 citations