Characterization of neuropeptide Y binding sites in rat cardiac ventricular membranes

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

Neuropeptide Y: complete amino acid sequence of the brain peptide.

1982 • 1,360 citations

Evidence for different pre- and post-junctional receptors for neuropeptide Y and related peptides

1986 • 632 citations

High levels of neuropeptide Y in peripheral noradrenergic neurons in various mammals including man

1983 • 610 citations

Central administration of neuropeptide Y induces hypotension bradypnea and EEG synchronization in the rat*

1983 • 292 citations

Y₁ and Y₂ receptors for neuropeptide Y

1989 • 183 citations

Effects of neuropeptide Y on the cardiovascular system

1987 • 183 citations

Prolonged non-adrenergic inhibition of cardiac vagal action following sympathetic stimulation: Neuromodulation by neuropeptide Y?

1985 • 182 citations

Effects of neuropeptide Y (NPY) on mechanical activity and neurotransmission in the heart, vas deferens and urinary bladder of the guinea‐pig

1984 • 177 citations

Neuropeptide Y (NPY) reduces myocardial perfusion and inhibits the force of contraction of the isolated perfused rabbit heart

1983 • 174 citations

High concentrations of a novel peptide, neuropeptide Y, in the innervation of mouse and rat heart.

1984 • 163 citations

Distribution and origin of substance P and neuropeptide Y-immunoreactive nerves in the guinea-pig heart

1986 • 155 citations

Neuropeptide Y inhibits cardiac adenylate cyclase through a pertussis toxin-sensitive G protein.

1987 • 130 citations

Neuropeptide Y receptor in pig spleen: binding characteristics, reduction of cyclic AMP formation and calcium antagonist inhibition of vasoconstriction

1988 • 127 citations

Neuropeptide Y: a putative neurotransmitter

1986 • 125 citations

Elevation of plasma neuropeptide Y levels in congestive heart failure

1989 • 115 citations

The vasoconstrictor effect of neuropeptide Y and related peptides in the guinea pig isolated heart

1986 • 115 citations

Neuropeptide Y (NPY) and the pig heart: Release and coronary vasoconstrictor effects

1986 • 99 citations

Neuropeptide Y-like immunoreactivity in cultured intrinsic neurones of the heart

1984 • 88 citations

Neuropeptide Y receptors and the inhibition of adenylate cyclase in the human frontal and temporal cortex

1987 • 85 citations

125I-neuropeptide Y and 125I-peptide YY bind to multiple receptor sites in rat brain.

1988 • 84 citations

Heart receptors for VIP, PHI and secretin are able to activate adenylate cyclase and to mediate inotropic and chronotropic effects. Species variations and physiopathology

1984 • 77 citations

Neuropeptide Y stimulates inositol phospholipid hydrolysis in rat brain miniprisms

1988 • 55 citations

Specific [3H]propionyl-neuropeptide Y (NPY) binding in rabbit aortic membranes: Comparisons with binding in rat brain and biological responses in rat vas deferens

1988 • 50 citations

High affinity binding of [3H]acetylcholine to muscarinic receptors. Regional distribution and modulation by guanine nucleotides.

1985 • 47 citations

Contractile effects of cardiac neuropeptides in isolated canine atrial and ventricular muscles

1989 • 44 citations

Characterization of specific pancreatic polypeptide receptors on basolateral membranes of the canine small intestine.

1988 • 41 citations

Characteristics of insulin receptors in the heart muscle Binding of insulin to isolated muscle cells from adult rat heart

1980 • 37 citations

Peptide YY receptors in the brain

1988 • 35 citations

Synthesis of neuropeptide Y*

1987 • 32 citations

The antiadrenergic effect of neuropeptide Y on the ventricular cardiomyocyte

1988 • 32 citations

Comparison of the effects of neuropeptide Y (NPY) and 4-norleucine-NPY on isolated perfused rat hearts; effects of NPY on atrial and ventricular strips of rat heart and on rabbit heart mitochondria

1988 • 32 citations

Synthesis and biological properties of 4-norleucine-neuropeptide Y; secondary structure of neuropeptide Y

1989 • 13 citations