Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes

The molecular biology of cytochrome P450s.

1988 • 1,294 citations

The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature

1991 • 1,092 citations

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

1989 • 910 citations

Enzyme induction in the cytochrome P-450 system

1990 • 631 citations

Phenobarbital induction of cytochrome P-450 gene expression

1992 • 530 citations

The regulation of gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1987 • 251 citations

Coding Nucleotide, 5′ Regulatory, and Deduced Amino Acid Sequences of P-450BM-3, a Single Peptide Cytochrome P-450:NADPH-P-450 Reductase from Bacillus megaterium

1989 • 242 citations

Negative regulation of serum-responsive enhancer elements

1989 • 144 citations

Phenobarbital induction of rat liver cytochromes P-450b and P-450e. Quantitation of specific RNAs by hybridization to synthetic oligodeoxyribonucleotide probes.

1985 • 128 citations

Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription

1991 • 115 citations

A barbiturate-regulated protein binding to a common sequence in the cytochrome P450 genes of rodents and bacteria.

1991 • 112 citations

Regulation of cytochrome P-450b/e and P-450p gene expression by growth hormone in adult rat hepatocytes cultured on a reconstituted basement membrane.

1990 • 108 citations

Superinduction of cytochrome P1-450 gene transcription by inhibition of protein synthesis in wild type and variant mouse hepatoma cells.

1985 • 107 citations

Tissue-specific expression of rat mRNAs homologous to cytochromes P-450b and P-450e

1986 • 88 citations

Differential Effects of Chromium(VI) on Constitutive and Inducible Gene Expression in Chick Embryo Liver In Vivo and Correlation With Chromium(VI)‐Induced DNA Damage

1989 • 79 citations

Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem

1989 • 77 citations

Regulation of cytochrome P-450 messenger RNA and apoprotein levels by heme.

1987 • 68 citations

The cDNA and protein sequence of a phenobarbital-induced chicken cytochrome P-450.

1986 • 52 citations

Regulation of cytochrome P-450 gene expression. Studies with a cloned probe.

1985 • 51 citations

Sequence of a Chicken Phenobarbital-Inducible Cytochrome P450 cDNA: Regulation of Two P450 mRNAs Transcribed from Different Genes

1989 • 49 citations

Transcriptional regulation of the chicken CYP2H1 gene. Localization of a phenobarbital-responsive enhancer domain.

1991 • 46 citations

Divergent effects of cycloheximide on the induction of Class II and Class III cytochrome P450 mRNAs in cultures of adult rat hepatocytes

1990 • 36 citations

Relationship of structure to fungitoxicity of cycloheximide and related glutarimide derivatives

1966 • 33 citations

Role of heme in phenobarbital induction of cytochromes P450 and 5-aminolevulinate synthase in cultured rat hepatocytes maintained on an extracellular matrix

1990 • 33 citations

Increases in cytochrome P-450 in cultured hepatocytes mediated by 3- and 4-carbon alcohols

1982 • 31 citations

Effect of serum proteins on haem uptake and metabolism in primary cultures of liver cells

1988 • 29 citations

Heme is a positive regulator of cytochrome P-450 gene transcription

1988 • 29 citations

Cycloheximide induces stromelysin mRNA in cultured human fibroblasts

1990 • 26 citations

Requirement for a 1-Kilobase 5′-Flanking Sequence for Barbiturate-inducible Expression of the Cytochrome P-450BM-3 Gene in Bacillus megaterium

1989 • 23 citations

Inhibitors of Translation Induce Low Density Lipoprotein Receptor Gene Expression in Human Skin Fibroblasts

1989 • 22 citations

A cycloheximide-inducible gene ofNeurospora crassabelongs to the cytochrome P-450 superfamily

1989 • 19 citations

Heme may not be a positive regulator of cytochrome‐P450 gene expression

1989 • 19 citations

Selective induction of cytochrome P450e by kepone (chlordecone) in primary cultures of adult rat hepatocytes.

1991 • 19 citations

Heme regulates cytochrome P-450 gene transcription elongation

1988 • 18 citations

Induction of Cytochrome P450 by Barbiturates in Chick Embryo Hepatocytes: A Quantitative Structure‐Activity Analysis

1990 • 18 citations

Expression of cytochrome P-450 and albumin genes in rat liver: effect of xenobiotics

1986 • 16 citations

Drug-induced porphyrin biosynthesis—XIII

1975 • 15 citations

Coordinate elevations of liver δ-aminolevulinate synthase and cytochrome P-450 RNA by phenobarbital in chicken embryos: The effects of heme

1989 • 15 citations

Differential effects of cycloheximide on rat liver cytochrome P-450 gene transcription in the whole animal and hepatoma cell culture

1987 • 13 citations

Involvement of heme in the transcriptional activation of CYPIIB1/B2 gene by phenobarbitone in rat liver—Studies with succinylacetone

1991 • 12 citations

A comparative study of tbe regulation of cytochrome P-450 and glutathione transferase gene expression in rat liver

1986 • 10 citations

Inducibility of rat liver cytochrome P-450IA1 (P-450c) mRNA during the partial inhibition of protein synthesis

1989 • 5 citations

Inhibition of Protein Biosynthesis: Its Significance in Drug Design

1971 • 4 citations