Covalent modifications of aminophospholipids by 4-hydroxynonenal

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1991 • 6,550 citations

The role of lipid peroxidation and antioxidants in oxidative modification of LDL

1992 • 2,335 citations

Low density lipoprotein undergoes oxidative modification in vivo.

1989 • 1,537 citations

Mechanisms of free radical oxidation of unsaturated lipids

1995 • 1,158 citations

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

1980 • 1,094 citations

Free Radicals, Lipid Peroxidation and Cancer

1982 • 530 citations

Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction.

1993 • 512 citations

Modification of histidine residues in proteins by reaction with 4-hydroxynonenal.

1992 • 481 citations

Biological interactions of α,β-unsaturated aldehydes

1989 • 328 citations

Free Radicals, Lipid Peroxidation and Cancer

1982 • 320 citations

Modification of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Formation of cross-linked protein that inhibits the multicatalytic protease.

1994 • 311 citations

Quantification of malondialdehyde and 4-hydroxynonenal adducts to lysine residues in native and oxidized human low-density lipoprotein

1997 • 288 citations

Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine.

1993 • 281 citations

Reaction of Glutathione with Conjugated Carbonyls

1975 • 256 citations

Michael Addition-Type 4-Hydroxy-2-nonenal Adducts in Modified Low-Density Lipoproteins: Markers for Atherosclerosis

1994 • 248 citations

Modification of human low-density lipoprotein by the lipid peroxidation product 4-hydroxynonenal

1986 • 241 citations

Structural Definition of Early Lysine and Histidine Adduction Chemistry of 4-Hydroxynonenal

1995 • 231 citations

Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids

1990 • 225 citations

A simple and efficient method for platelet isolation from their plasma

1980 • 186 citations

Pyrrole formation from 4-hydroxynonenal and primary amines

1993 • 172 citations

The reaction of cysteine with α,β-unsaturated aldehydes

1976 • 160 citations

4-Hydroxy-2-Nonenal Pyrrole Adducts in Human Neurodegenerative Disease

1997 • 155 citations

Extraction and partial characterization of dialysable products originating from the peroxidation of liver microsomal lipids and inhibiting microsomal glucose 6-phosphatase activity

1979 • 81 citations

Studies on platelet lipoxygenase specificity towards icosapolyenoic and docosapolyenoic acids

1985 • 22 citations

Über die Bindung von 4-Hydroxy-2.3-enalen an Protein-SH-Gruppen

1968 • 15 citations