Characterization of Insulin-Degrading Activity of Intact and Subcellular Components of Human Fibroblasts*

Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase

1961 • 1,041 citations

Specific Assays of some Phosphatases in Subcellular Fractions of Small Intestinal Mucosa

1965 • 445 citations

Binding and degradation of 125I-insulin by rat hepatocytes.

1975 • 419 citations

Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study.

1979 • 223 citations

Insulin Metabolism and Degradation*

1981 • 197 citations

Purification of Insulin-Specific Protease by Affinity Chromatography

1972 • 119 citations

Stoichiometric binding and regulation of insulin receptors on human diploid fibroblasts using physiologic insulin levels.

1979 • 93 citations

Initial site of insulin cleavage by insulin protease.

1979 • 84 citations

In Vivo Chloroquine-induced Inhibition of Insulin Degradation in a Diabetic Patient with Severe Insulin Resistance

1984 • 72 citations

Degradation of Insulin and Proinsulin by Various Organ Homogenates of Rat

1972 • 68 citations

Insulin stimulation of glucose entry in cultured human fibroblasts

1979 • 66 citations

Peptide intermediates in the cellular metabolism of insulin.

1982 • 61 citations

Metabolism of Insulin and Glucagon. Breakdown of Radioiodinated Insulin and Glucagon in Rat Liver Cell Fractions

1971 • 60 citations

The distribution of sodium-potassium-activated adenosine triphosphatase in medulla and cortex of the kidney

1971 • 59 citations

Insulin degradation I. Purification and properties of glutathione-insulin transhydrogenase of rat liver

1972 • 56 citations

Isolation and characterization of a rough microsomal fraction from rat kidney that is enriched in lysosomal enzymes

1973 • 50 citations

Intracellular processing of epidermal growth factor. II. Intracellular cleavage of the COOH-terminal region of 125I-epidermal growth factor.

1984 • 49 citations

Early Detection of Degraded A14-125I-Insulin in Human Fibroblasts by the Use of High Performance Liquid Chromatography

1983 • 32 citations

Insulin degradation by human skeletal muscle

1982 • 27 citations

A Rapid Means of Separating A14-125I-Insulin from Heterogeneously Labeled Insulin Molecules for Biologic Studies

1982 • 26 citations

Substrate Studies for Insulin-Specific Protease

1973 • 22 citations

Insulin Stimulation of Glycogen Synthase in Cultured Human Diploid Fibroblasts

1980 • 20 citations

Insulin Activates Glycogen Synthase in Cultured Human Fibroblasts

1980 • 16 citations

The Fate of Insulin in Rat Hepatocytes: Evidence for the Release of an Immunologically Active Fragment

1984 • 16 citations

Activation of Pyruvate Dehydrogenase Complex by Porcine and Biosynthetic Human Insulin in Cultured Human Fibroblasts

1984 • 14 citations