Phenobarbitone-Mediated Translocation of the Cytosolic Proteins Interacting with the 5′-Proximal Region of Rat Liver CYP2B1/B2 Gene into the Nucleus

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene

1998 • 697 citations

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

2000 • 641 citations

Enzyme induction in the cytochrome P-450 system

1990 • 631 citations

Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene

1999 • 537 citations

Diverse Roles of the Nuclear Orphan Receptor CAR in Regulating Hepatic Genes in Response to Phenobarbital

2002 • 455 citations

A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor.

1986 • 412 citations

Phenobarbital Response Elements of Cytochrome P450 Genes and Nuclear Receptors

2001 • 357 citations

Activation by Diverse Xenochemicals of the 51-Base Pair Phenobarbital-Responsive Enhancer Module in theCYP2B10Gene

1998 • 160 citations

Localization of a phenobarbital-responsive element (PBRE) in the 5′-flanking region of the rat CYP2B2 gene

1995 • 156 citations

Characterization of a Phenobarbital-responsive Enhancer Module in Mouse P450 Cyp2b10 Gene

1997 • 139 citations

The interaction between exogenous DNA and sperm cells

1992 • 123 citations

Characterization of Phenobarbital-inducible Mouse Cyp2b10 Gene Transcription in Primary Hepatocytes

1996 • 109 citations

Phenobarbital Induction Mediated by a Distal CYP2B2 Sequence in Rat Liver Transiently Transfected in Situ

1996 • 101 citations

Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes

1998 • 99 citations

Cell- and sequence-specific binding of nuclear proteins to 5′-flanking DNA of the rat growth hormone gene.

1987 • 90 citations

The CYP2B2 Phenobarbital Response Unit Contains an Accessory Factor Element and a Putative Glucocorticoid Response Element Essential for Conferring Maximal Phenobarbital Responsiveness

1998 • 88 citations

Phenobarbital induction and tissue-specific expression of the rat CYP2B2 gene in transgenic mice.

1993 • 86 citations

The Role of Barbie Box Sequences as cis-Acting Elements Involved in the Barbiturate-mediated Induction of Cytochromes P450BM−1 and P450BM−3 in Bacillus megaterium

1995 • 82 citations

Two-dimensional electrophoresis of proteins of citric acid nuclei prepared with aid of a Tissumizer®

1973 • 68 citations

Extent and character of phenobarbital-mediated changes in gene expression in the liver.

1997 • 59 citations

Regulation of cytochrome P-450b/e gene expression by a heme- and phenobarbitone-modulated transcription factor.

1989 • 58 citations

A Conserved Nuclear Receptor Consensus Sequence (DR-4) Mediates Transcriptional Activation of the Chicken CYP2H1 Gene by Phenobarbital in a Hepatoma Cell Line

2000 • 42 citations

A model for the transcriptional regulation of the CYP2B1/B2 gene in rat liver.

1995 • 37 citations

Regulation of Cytochrome P450 Gene Transcription by Phenobarbital

1998 • 35 citations

Identification and functional characterization of acis-acting positive DNA element regulating CYP 2B1/B2 gene transcription in rat liver

1992 • 35 citations

Transcriptional regulation of rat alpha 1-acid glycoprotein gene by phenobarbital.

1994 • 32 citations

Involvement of Synthesis and Phosphorylation of Nuclear Protein Factors That Bind to the Positivecis-Acting Element in the Transcriptional Activation of the CYP2B1/B2 Gene by Phenobarbitonein Vivo

1996 • 30 citations

Interaction of Proteins with a Cytochrome P450 2B2 Gene Promoter: Identification of Two DNA Sequences That Bind Proteins That Are Enriched or Activated in Response to Phenobarbital

1994 • 25 citations

In VivoPhenobarbital Treatment Increases Protein Binding to a Putative AP-1 Site in the CYP2B2 Promoter

1996 • 17 citations

Analysis of a Phenobarbital-Responsive Enhancer Sequence Located in the 5′ Flanking Region of the ChickenCYP2H1Gene: Identification and Characterization of Functional Protein-Binding Sites

1999 • 15 citations

Receptor-Mediated Gene Delivery Approach Demonstrates the Role of 5′-Proximal DNA Region in Conferring Phenobarbitone Responsiveness to CYP2B2 Gene in Rat Liver in Vivo

2000 • 8 citations

A Significant Decrease of the Transcriptional Activity of p53 Mutants Deriving from Human Functional Adrenal Tumors

1996 • 7 citations