Antiplatelet agents and anticoagulants for hypertension

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

2002 • 9,810 citations

A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)

1996 • 6,350 citations

Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial

1998 • 5,793 citations

Cochrane Handbook for Systematic Reviews of Interventions

2010 • 5,340 citations

Blood pressure, stroke, and coronary heart disease

1990 • 4,424 citations

Blood pressure, stroke, and coronary heart disease *1Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias

1990 • 4,310 citations

1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension

1999 • 3,718 citations

COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS

1994 • 3,408 citations

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

1994 • 2,993 citations

Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study

2002 • 2,510 citations

Final Report on the Aspirin Component of the Ongoing Physicians' Health Study

1989 • 2,180 citations

A Randomized Trial Comparing Ticlopidine Hydrochloride with Aspirin for the Prevention of Stroke in High-Risk Patients

1989 • 1,209 citations

Randomised trial of prophylactic daily aspirin in British male doctors

1988 • 1,178 citations

A Comparison of Warfarin and Aspirin for the Prevention of Recurrent Ischemic Stroke

2001 • 1,172 citations

The United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: final results.

1991 • 1,145 citations

British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary

2004 • 847 citations

Antiplatelet agents for preventing pre-eclampsia and its complications

2007 • 846 citations

Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk

1998 • 759 citations

1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension. Guidelines Subcommittee.

1999 • 665 citations

Blood pressure, antihypertensive drug treatment and the risks of stroke and of coronary heart disease

1994 • 603 citations

Guidelines for management of hypertension: report of the third working party of the British Hypertension Society

1999 • 590 citations

Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration.

1994 • 566 citations

A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial origin

1997 • 478 citations

Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke Prevention in Atrial Fibrillation II Study*1

1994 • 421 citations

Cyclooxygenase-2???Specific Inhibitors and Cardiorenal Function: A Randomized, Controlled Trial of Celecoxib and Rofecoxib in Older Hypertensive Osteoarthritis Patients

2001 • 333 citations

Exercise and Risk of Stroke in Male Physicians

1999 • 283 citations

Superiority of Clopidogrel Versus Aspirin in Patients With Prior Cardiac Surgery

2001 • 283 citations

The Risk of Stroke in Patients with Acute Myocardial Infarction after Thrombolytic and Antithrombotic Treatment

1992 • 282 citations

DRUG-INDUCED INHIBITION OF PLATELET FUNCTION DELAYS PROGRESSION OF PERIPHERAL OCCLUSIVE ARTERIAL DISEASE

1985 • 261 citations

1993 Guidelines for the management of mild hypertension: memorandum from a World Health Organization/International Society of Hypertension meeting

1993 • 258 citations

1993 Guidelines for the management of mild hypertension: MEMORANDUM from a World Health Organization/International Society of Hypertension meeting

1993 • 236 citations

Long-Term Treatment with a Platelet Glycoprotein-Receptor Antagonist after Percutaneous Coronary Revascularization

2000 • 218 citations

Oral anticoagulants versus antiplatelet therapy for preventing stroke in patients with non-valvular atrial fibrillation and no history of stroke or transient ischemic attacks

2007 • 212 citations

Relation of Endothelium, Thrombogenesis, and Hemorheology in Systemic Hypertension to Ethnicity and Left Ventricular Hypertrophy

1997 • 165 citations

Comparative Safety and Tolerability of Clopidogrel and Aspirin

1999 • 159 citations

Three Important Subgroups of Hypertensive Persons at Greater Risk of Intracerebral Hemorrhage

1998 • 150 citations

Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. The Medical Research Council's General Practice Research Framework.

1998 • 145 citations

Prediction of 1-Year Survival After Thrombolysis for Acute Myocardial Infarction in the Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries Trial

2000 • 144 citations

Alcohol Consumption and Risk of Coronary Heart Disease by Diabetes Status

2000 • 143 citations

Reduction in the need for hospitalization for recurrent ischemic events and bleeding with clopidogrel instead of aspirin

2000 • 140 citations

Treatment of poor-prognosis early rheumatoid arthritis: A randomized study of treatment with methotrexate, cyclosporin A, and intraarticular corticosteroids compared with sulfasalazine alone

2000 • 135 citations

Anticoagulant therapy after acute myocardial infarction. Relation of therapeutic benefit to patient's age, sex, and severity of infarction

1972 • 135 citations

Determination of who may derive most benefit from aspirin in primary prevention: subgroup results from a randomised controlled trial

2000 • 124 citations

Anticoagulant Therapy After Acute Myocardial Infarction

1972 • 114 citations

Endothelial dysfunction in hypertension.

1996 • 113 citations

Diabetes Mellitus, Glycoprotein IIb/IIIa Blockade, and Heparin

1998 • 110 citations

Effect of indomethacin on blood pressure in elderly people with essential hypertension well controlled on amlodipine or enalapril

2000 • 102 citations

Effects of low-dose aspirin on clinic and ambulatory blood pressure in treated hypertensive patients

2000 • 100 citations

Gastroduodenal Tolerance of 75 mg Clopidogrel versus 325 mg Aspirin in Healthy Volunteers: A Gastroscopic Study

2000 • 97 citations

Active-control trials: How would a new agent compare with placebo? A method illustrated with clopidogrel, aspirin, and placebo

2001 • 88 citations

Risk of primary intracerebral haemorrhage associated with aspirin and non-steroidal anti-inflammatory drugs: case-control study

1999 • 84 citations

Stroke in Patients With Acute Coronary Syndromes

1999 • 81 citations

The role of rheological and haemostatic factors in hypertension

1997 • 81 citations

Endothelial Dysfunction in Hypertension

1997 • 80 citations

Use of Aspirin, Epistaxis, and Untreated Hypertension as Risk Factors for Primary Intracerebral Hemorrhage in Middle-Aged and Elderly People

2001 • 79 citations

The Effects of Nonsteroidal Anti-inflammatory Drugs on Blood Pressures of Patients With Hypertension Controlled by Verapamil

1995 • 75 citations

Abnormalities of rheology and coagulation in hypertension.

1994 • 73 citations

Intracerebral Hemorrhage in Blacks

1997 • 72 citations

Influence of non-steroidal anti-inflammatory drugs on renal function and 24 h ambulatory blood pressure-reducing effects of enalapril and nifedipine gastrointestinal therapeutic system in hypertensive patients

1995 • 62 citations

Effect of aspirin on blood pressure in hypertensive patients taking enalapril or losartan

1999 • 59 citations

British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary

2004 • 58 citations

Effects of Aspirin on Angiotensin-Converting Enzyme Inhibition and Left Ventricular Dilation One Year After Acute Myocardial Infarction

1998 • 58 citations

Aspirin, Warfarin, or the Combination for Secondary Prevention of Coronary Events in Patients With Acute Coronary Syndromes and Prior Coronary Artery Bypass Surgery

2001 • 57 citations

Randomized trial of thrombolysis versus heparin in unstable angina.

1992 • 54 citations

Potential mechanisms by which nonsteroidal anti-inflammatory drugs elevate blood pressure: the role of endothelin-1.

1996 • 54 citations

Incidence of thrombotic occlusion and major adverse cardiac events between two and four weeks after coronary stent placement: analysis of 5,678 patients with a four-week ticlopidine regimen

2001 • 51 citations

Preventive Treatment of Cerebral Transient Ischemia: Comparative Randomized Trial of Pentoxifylline versus Conventional Antiaggregants

1985 • 50 citations

A Study of the Association between Epistaxis and the Severity of Hypertension

1998 • 45 citations

Secondary Stroke Prevention with Low-Dose Aspirin, Sustained Release Dipyridamole Alone and in Combination

1998 • 42 citations

Influence of Aspirin Usage on Blood Pressure: Dose and Administration-Time Dependencies

1997 • 42 citations

Non-Steroidal Anti-Inflammatory Drugs and Blood Pressure

1982 • 42 citations

Comparative effects of nabumetone, sulindac, and ibuprofen on renal function.

1997 • 40 citations

Relative role of factors associated with cerebral infarction and cerebral hemorrhage. A matched pair case-control study.

1977 • 39 citations

The influence of ticlopidine on the natural course of retinal vein occlusion.

1984 • 39 citations

The Impact of Ibuprofen on the Efficacy of Antihypertensive Treatment With Hydrochlorothiazide in Elderly Persons

1996 • 38 citations

Assessment of blood pressure during naproxen therapy in hypertensive patients treated with nicardipine

1995 • 36 citations

Enhanced blood pressure response to cyclooxygenase inhibition in salt-sensitive human essential hypertension.

1993 • 32 citations

Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm

2000 • 32 citations

Interaction of indomethacin with felodipine and enalapril

1993 • 25 citations

Effect of aspirin on mortality in women with symptomatic or silent myocardial ischemia

1996 • 25 citations

Should patients with hypertension receive antithrombotic therapy?

2001 • 24 citations

Effects of captopril and ticlopidine, alone or in combination, in hypertensive patients with intermittent claudication.

1996 • 24 citations

Controlled trial of aspirin in cerebral ischemia

1986 • 23 citations

Antihypertensive effect of the combination of fosinopril and HCTZ is resistant to interference by nonsteroidal antiinflammatory drugs

1999 • 23 citations

Comparison of two aspirin doses on ischemic stroke in post-myocardial infarction patients in the warfarin (Coumadin) Aspirin Reinfarction Study (CARS)

2001 • 23 citations

Indomethacin and cyclosporin together produce marked renal vasoconstriction in humans

1994 • 23 citations

Assessment of Blood Pressure During Treatment with Naproxen or Ibuprofen in Hypertensive Patients Treated with Hydrochlorothiazide

1993 • 23 citations

Clopidogrel compatibility with concomitant cardiac co-medications: a study of its interactions with a beta-blocker and a calcium uptake antagonist.

1999 • 21 citations

Clinical risk factors for ischemic complications after percutaneous coronary interventions: Results from the EPIC trial

1999 • 21 citations

Renovascular Effects of Nonprescription Ibuprofen in Elderly Hypertensive Patients With Mild Renal Impairment

1993 • 21 citations

Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril.

1993 • 21 citations

Hemodynamic and Humoral Effects of Low-Dose Aspirin in Treated and Untreated Essential Hypertensive Patients

1994 • 19 citations

Interaction between nonsteroidal anti-inflammatory drug intake and calcium-channel blocker-based antihypertensive treatment in the Syst-Eur trial

2001 • 17 citations

Effects of non‐steroidal anti‐inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension.

1990 • 17 citations

Haemodynamic changes induced by the correction of anaemia by erythropoietin: role of antiplatelet therapy

1995 • 17 citations

Does chronic aspirin treatment increase blood pressure in man?

1981 • 16 citations

No Adverse Effect of Non-Steroidal Anti-Inflammatory Drugs, Sulindac and Diclofenac Sodium, on Blood Pressure Control with a Calcium Antagonist, Nifedipine, in Elderly Hypertensive Patients.

1991 • 15 citations

Do trandolapril and indomethacin influence renal function and renal functional reserve in hypertensive patients?

1997 • 15 citations

Effect of Indomethacin on Blood Pressure Control during Treatment with Nitrendipine

1995 • 13 citations

Ticlopidine Lowers Plasma Fibrinogen in Patients with Polycythaemia Rubra Vera and Additional Thrombotic Risk Factors

1991 • 13 citations

Effect of Ketoprofen on Blood Pressure, Endocrine and Renal Responses to Chronic Dosing with Captopril in Patients with Essential Hypertension

1992 • 12 citations

Efficacy of Antiplatelet Treatment in Hypertensive Patients with TIA or Stroke

1998 • 11 citations

Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients

1996 • 11 citations

Amlodipine and haemodynamic effects of cyclo‐oxygenase inhibition.

1995 • 10 citations

Antiplatelet Therapy Is Effective in Primary Prevention of Myocardial Infarction in Patients With a Previous Cerebrovascular Ischemic Event

1993 • 10 citations

Introduction: The Quality of the Medical Evidence: Is It Good Enough?

1996 • 9 citations

Indomethacin raises blood pressure in untreated essential hypertensives

1991 • 8 citations

Study on the possible interaction between tenoxicam and atenolol in hypertensive patients.

1995 • 6 citations

Treatment of hypertension with dihydropyridine calcium antagonists and aspirin.

1994 • 6 citations

Different patterns of renal prostaglandins I2 and E2 in patients with essential hypertension with low to normal or high renin activity

2000 • 5 citations

[Reduction of the antihypertensive effects of enalapril by indomethacin. Its independence from renal sodium retention].

1996 • 4 citations

Is Dad mad, doctor?

2004 • 2 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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