Reduction in the need for hospitalization for recurrent ischemic events and bleeding with clopidogrel instead of aspirin

COLLABORATIVE OVERVIEW OF RANDOMIZED TRIALS OF ANTIPLATELET THERAPY .1. PREVENTION OF DEATH, MYOCARDIAL-INFARCTION, AND STROKE BY PROLONGED ANTIPLATELET THERAPY IN VARIOUS CATEGORIES OF PATIENTS

1994 • 3,408 citations

Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

1994 • 2,993 citations

The Effect of Digoxin on Mortality and Morbidity in Patients with Heart Failure

1997 • 2,867 citations

急性心筋梗塞の疑いのある17187症例におけるストレプトキナーゼ静脈内投与,アスピリン経口投与,上記2つの併用または無処置の無作偽試験 ISIS-2

1988 • 2,760 citations

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.

1988 • 2,740 citations

A Randomized Trial Comparing Ticlopidine Hydrochloride with Aspirin for the Prevention of Stroke in High-Risk Patients

1989 • 1,209 citations

Randomized, Controlled Trial of Long-Term Moderate Exercise Training in Chronic Heart Failure

1999 • 1,100 citations

Secondary prevention of vascular disease by prolonged antiplatelet treatment

1988 • 962 citations

RANDOMISED TRIAL OF INTRAVENOUS STREPTOKINASE, ORAL ASPIRIN, BOTH, OR NEITHER AMONG 17 187 CASES OF SUSPECTED ACUTE MYOCARDIAL INFARCTION: ISIS-2

1988 • 848 citations

Readmission After Hospitalization for Congestive Heart Failure Among Medicare Beneficiaries

1997 • 836 citations

Platelet Glycoprotein IIb/IIIa Receptors in Cardiovascular Medicine

1995 • 769 citations

Adverse outcomes of underuse of beta-blockers in elderly survivors of acute myocardial infarction

1997 • 426 citations

Development of aspirin resistance in persons with previous ischemic stroke.

1994 • 412 citations

Adverse Outcomes of Underuse of β-Blockers in Elderly Survivors of Acute Myocardial Infarction

1997 • 301 citations

Acute Coronary Syndromes in the GUSTO-IIb Trial

1998 • 259 citations

Prevention of readmission in elderly patients with congestive heart failure

1993 • 257 citations

Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial

2000 • 245 citations

Incidence and Clinical Course of Thrombotic Thrombocytopenic Purpura Due to Ticlopidine Following Coronary Stenting

1999 • 235 citations

Aspirin response and failure in cerebral infarction.

1993 • 228 citations

Variation among Hospitals in Coronary-Angiography Practices and Outcomes after Myocardial Infarction in a Large Health Maintenance Organization

1996 • 183 citations

Economic Assessment of Low-Molecular-Weight Heparin (Enoxaparin) Versus Unfractionated Heparin in Acute Coronary Syndrome Patients

1998 • 176 citations

In-Hospital and One-Year Economic Outcomes After Coronary Stenting or Balloon Angioplasty

1995 • 174 citations

Clopidogrel

1997 • 155 citations

Epidemic of Cardiovascular Disease and Stroke: The Three Main Challenges

1999 • 132 citations

Clopidogrel Inhibition of Stent, Graft, and Vascular Thrombogenesis With Antithrombotic Enhancement by Aspirin in Nonhuman Primates

1998 • 126 citations

Invasive versus conservative strategies in unstable angina and non\NQ-wave myocardial infarction following treatment with tirofiban: rationale and study design of the international TACTICS-TIMI 18 trial

1998 • 119 citations

Acute Hemodynamic Interaction of Aspirin and Ticlopidine With Enalapril

1998 • 117 citations

Outcomes for Older Men and Women with Congestive Heart Failure

1997 • 116 citations

Long-Term Oral Anticoagulant Therapy in Patients With Unstable Angina or Suspected Non–Q-Wave Myocardial Infarction

1998 • 115 citations

Impact of angiotensin-converting enzyme inhibitor underdosing on rehospitalization rates in congestive heart failure

1998 • 75 citations

Choice of endpoints in antiplatelet trials

2000 • 65 citations

The Sequelae of Hospitalization for Congestive Heart Failure Among Older Adults

1997 • 65 citations

An approach to evaluating thrombolytic therapy in acute myocardial infarction. The 'unsatisfactory outcome' end point.

1992 • 62 citations

Ultrastructural Studies of Platelet Aggregates From Human Subjects Receiving Clopidogrel and From a Patient With an Inherited Defect of an ADP-Dependent Pathway of Platelet Activation

1996 • 62 citations

Superiority of “triple” drug therapy in heart failure: insights from the PROVED and RADIANCE trials

1998 • 48 citations

Economics of Treating Heart Failure

1997 • 47 citations

Health outcomes associated with beta-blocker and diltiazem treatment of unstable angina

1998 • 45 citations

Long-term oral platelet glycoprotein IIb/IIIa receptor antagonism with sibrafiban after acute coronary syndromes: Study design of the Sibrafiban versus aspirin to Yield Maximum Protection from ischemic Heart events post-acute cOroNary sYndromes (SYMPHONY) trial

1999 • 45 citations

Effect of aspirin and clopidogrel on platelet-dependent tissue factor expression in endothelial cells

1994 • 36 citations

Rehospitalization in surviving patients of out-of-hospital ventricular fibrillation (the CASCADE study)

1993 • 9 citations

Death, mode of death, morbidity and requirement for rehospitalization during 2 years after coronary artery bypass grafting in relation to preoperative ejection fraction

1996 • 9 citations

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