The Inhibitory Role of B7-H4 in Antitumor Immunity: Association with Cancer Progression and Survival

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

2006 • 705 citations

B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell Immunity

2003 • 665 citations

B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

2004 • 595 citations

B7S1, a Novel B7 Family Member that Negatively Regulates T Cell Activation

2003 • 407 citations

B7x: A widely expressed B7 family member that inhibits T cell activation

2003 • 380 citations

B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome

2007 • 358 citations

Relationship between B7-H4, Regulatory T Cells, and Patient Outcome in Human Ovarian Carcinoma

2007 • 310 citations

B7-H3 and B7-H4 expression in non-small-cell lung cancer

2006 • 295 citations

B7-H4 expression in renal cell carcinoma and tumor vasculature: Associations with cancer progression and survival

2006 • 289 citations

Cutting Edge: Induction of B7-H4 on APCs through IL-10: Novel Suppressive Mode for Regulatory T Cells

2006 • 277 citations

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

2005 • 241 citations

Genomic Organization and Expression Analysis of B7-H4, an Immune Inhibitory Molecule of the B7 Family

2003 • 238 citations

B7-H4 Is Highly Expressed in Ductal and Lobular Breast Cancer

2005 • 210 citations

The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation

2005 • 205 citations

Assessing Lead Time of Selected Ovarian Cancer Biomarkers: A Nested Case–Control Study

2009 • 203 citations

B7-H4 Is a Novel Membrane-Bound Protein and a Candidate Serum and Tissue Biomarker for Ovarian Cancer

2006 • 179 citations

Fine tuning the immune response through B7‐H3 and B7‐H4

2009 • 165 citations

Attenuating Lymphocyte Activity

2005 • 158 citations

B7-H4 overexpression in ovarian tumors

2005 • 138 citations

B7-H4 Expression in Human Melanoma: Its Association with Patients' Survival and Antitumor Immune Response

2011 • 131 citations

B7-H4 expression associates with cancer progression and predicts patient’s survival in human esophageal squamous cell carcinoma

2011 • 120 citations

Differential gene expression profiles between tumor biopsies and short-term primary cultures of ovarian serous carcinomas: Identification of novel molecular biomarkers for early diagnosis and therapy

2006 • 106 citations

B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration

2007 • 104 citations

Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer

2007 • 102 citations

Prediction of ovarian cancer prognosis and response to chemotherapy by a serum-based multiparametric biomarker panel

2008 • 100 citations

Tumor expression of B7-H4 predicts poor survival of patients suffering from gastric cancer

2010 • 89 citations

B7-H4–deficient mice display augmented neutrophil-mediated innate immunity

2008 • 80 citations

Serum-Soluble B7x Is Elevated in Renal Cell Carcinoma Patients and Is Associated with Advanced Stage

2008 • 79 citations

Generation and Characterization of B7-H4/B7S1/B7x-Deficient Mice

2006 • 74 citations

B7-H4 is over-expressed in early-stage ovarian cancer and is independent of CA125 expression

2007 • 67 citations

Detection of B7-H4 and p53 in Pancreatic Cancer

2008 • 66 citations

Breaking down the barriers to cancer immunotherapy

2005 • 62 citations

B7-H4 Expression Promotes Tumorigenesis in Ovarian Cancer

2009 • 62 citations

B7-H4 Expression in a Range of Breast Pathology: Correlation With Tumor T-cell Infiltration

2007 • 60 citations

Immune Signatures of Murine and Human Cancers Reveal Unique Mechanisms of Tumor Escape and New Targets for Cancer Immunotherapy

2007 • 55 citations

Expression of B7‐H4 in blood of patients with gastric cancer predicts tumor progression and prognosis

2010 • 39 citations

Conclusions and future prospects

1989 • 38 citations

B7-H4 reverse signaling induces the apoptosis of EBV-transformed B cells through Fas ligand up-regulation

2008 • 34 citations

Cell cycle arrest induced by engagement of B7‐H4 on Epstein–Barr virus‐positive B‐cell lymphoma cell lines

2009 • 32 citations

B7-H4 expression in various tumors determined using a novel developed monoclonal antibody

2010 • 30 citations

Impaired negative regulation of homeostatically proliferating T cells

2008 • 18 citations

The Relationship between B7-H4 Expression and Clinicopathological Characteristics in Clinical Stage T1 Conventional Renal Cell Carcinoma

2011 • 15 citations