Adhesion and Activation of Human Platelets Induced by Convulxin Involve Glycoprotein VI and Integrin α2ॆ1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

A patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesion.

1989 • 468 citations

Identification of a 160,000 dalton platelet membrane protein that mediates the initial divalent cation-dependent adhesion of platelets to collagen

1986 • 409 citations

Biochemical mechanisms of platelet activation

1989 • 370 citations

Platelet Activation and Signal Transduction by Convulxin, a C-type Lectin from Crotalus durissus terrificus (Tropical Rattlesnake) Venom via the p62/GPVI Collagen Receptor

1997 • 345 citations

Biochemical mechanisms of platelet activation

1989 • 328 citations

Integrin α2β1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for α2β1-independent platelet reactivity

1995 • 311 citations

Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins

1989 • 305 citations

A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia

1987 • 270 citations

Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading

1986 • 211 citations

Deficiency of intact thrombospondin and membrane glycoprotein Ia in platelets with defective collagen-induced aggregation and spontaneous loss of disorder

1988 • 194 citations

The α2β1 Integrin Is a Necessary Co-receptor for Collagen-induced Activation of Syk and the Subsequent Phosphorylation of Phospholipase Cγ2 in Platelets

1996 • 160 citations

Variability of integrin alpha 2 beta 1 activity on human platelets

1993 • 155 citations

Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc γ-IIA receptor

1995 • 151 citations

Collagen stimulates tyrosine phosphorylation of phospholipase C‐γ2 but not phospholipase C‐γ1 in human platelets

1994 • 141 citations

Evidence for a role for tyrosine phosphorylation of phospholipase Cγ2 in collagen-induced platelet cytosolic calcium mobilization

1994 • 111 citations

COnvulxin, a potent platelet-aggregating protein from Crotalus durissus terrificus venom, specifically binds to platelets

1997 • 106 citations

Deficiency of P62, a putative collagen receptor, in platelets from a patient with defective collagen‐induced platelet aggregation

1992 • 93 citations

Cyclic AMP-insensitive Activation of c-Src and Syk Protein-tyrosine Kinases through Platelet Membrane Glycoprotein VI

1995 • 92 citations

Platelet Activation: Signal Transduction Via Membrane Receptors

1995 • 90 citations

Convulxin, a new toxin from the venom of the South American rattlesnake Crotalus durissus terrificus

1981 • 79 citations

Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella

1980 • 68 citations

Snake venom proteins modulating the interaction between von Willebrand factor and platelet glycoprotein Ib.

1996 • 51 citations

Snake Venom Proteins Modulating the Interaction between von Willebrand Factor and Platelet Glycoprotein lb

1996 • 35 citations

Convulxin-induced activation of intact and of thrombin-degranulated rabbit platelets: Specific crossed desensitisation with collagen

1983 • 30 citations

Convulxin-induced platelet aggregation is accompanied by a powerful activation of the phospholipase C pathway

1994 • 30 citations

I - Isolation and electron microscope studies of a potent platelet-aggregating glycoprotein from the venom of Crotalus durissus cascavella

1983 • 25 citations

II — Subunit structure of a potent platelet-activating glycoprotein isolated from the venom of Crotalus durissus cascavella

1984 • 24 citations

Human Gamma-Thrombin: Lack of Correlation Between a Platelet Functional Response and Glycoprotein V Hydrolysis

1987 • 24 citations

Two-way trafficking of membrane glycoproteins on thrombin-activated human platelets.

1994 • 14 citations

Electron microscopic cytochemistry on the distribution of wheat germ agglutinin receptor on the platelet plasma membrane after treatment with convulxin isolated from Crotalus durissus terrificus venom

1992 • 10 citations