Characterization of a Novel Analogue of 1α,25(OH)₂-Vitamin D₃ with Two Side Chains: Interaction with Its Nuclear Receptor and Cellular Actions

The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed

1998 • 1,391 citations

The Role of the Vitamin D Endocrine System in Health and Disease

1989 • 1,041 citations

A structural role for hormone in the thyroid hormone receptor

1995 • 938 citations

Disorders of Bone and Mineral Metabolism

1992 • 713 citations

20-EPI-vitamin D3 analogues: A novel class of potent regulators of cell growth and immune responses

1991 • 320 citations

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

1990 • 313 citations

Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia.

1994 • 310 citations

Stereocontrolled total synthesis of 1.alpha.,25-dihydroxycholecalciferol and 1.alpha.,25-dihydroxyergocalciferol

1986 • 226 citations

Distinct Conformational Changes Induced by 20-epi Analogues of 1α,25-Dihydroxyvitamin D3 Are Associated with Enhanced Activation of the Vitamin D Receptor

1995 • 201 citations

Isolation and Characterization of a Novel Coactivator Protein, NCoA-62, Involved in Vitamin D-mediated Transcription

1998 • 146 citations

Stimulation by 1α,25(OH)2-Vitamin D3 of Whole Cell Chloride Currents in Osteoblastic ROS 17/2.8 Cells

1997 • 100 citations

Chemistry and conformation of vitamin D molecules

1995 • 84 citations

A new series of vitamin D analogs is highly active for clonal inhibition, differentiation, and induction of WAF1 in myeloid leukemia

1996 • 81 citations

An asymmetric synthesis and absolute configuration of (S)(-)-deplancheine

1986 • 76 citations

A water-vapour giga-maser in the active galaxy TXFS2226 – 184

1995 • 76 citations

Retinoid X Receptor:Vitamin D₃ Receptor Heterodimers Promote Stable Preinitiation Complex Formation and Direct 1,25-Dihydroxyvitamin D₃-Dependent Cell-Free Transcription

1997 • 74 citations

Conformationally Restricted Analogs of 1α,25-Dihydroxyvitamin D₃ and Its 20-Epimer: Compounds for Study of the Three-Dimensional Structure of Vitamin D Responsible for Binding to the Receptor

1996 • 65 citations

Studies of vitamin D (calciferol) and its analogs. 39. Arocalciferols: synthesis and biological evaluation of aromatic side-chain analogs of 1.alpha.,25-dihydroxyvitamin D3

1991 • 64 citations

Synergistic decrease of clonal proliferation, induction of differentiation, and apoptosis of acute promyelocytic leukemia cells after combined treatment with novel 20-epi vitamin D3 analogs and 9-cis retinoic acid.

1997 • 63 citations

Conformation−Function Relationship of Vitamin D: Conformational Analysis Predicts Potential Side-Chain Structure

1998 • 62 citations

Vitamin D: Structure‐function analyses and the design of analogs

1992 • 61 citations

1 alpha,25-Dihydroxy-20-epi-vitamin D3: an extraordinarily potent inhibitor of leukemic cell growth in vitro

1994 • 60 citations

Effect of C2O stereochemistry on the conformational profile of the side chains of vitamin D analogs.

1993 • 52 citations

Three-dimensional model of the ligand binding domain of the nuclear receptor for 1?,25-dihydroxy-vitamin D3

1999 • 48 citations

A 20-epi side chain restores growth-regulatory and transcriptional activities of an A ring-modified hybrid analog of 1α,25-dihydroxyvitamin D3 without increasing its affinity to the vitamin D receptor

1996 • 38 citations

Untitled

1998 • 30 citations

Synthetic 20‐Epi Analogs of Calcitriol are Potent Inducers of Target‐Gene Activation in Osteoblastic Cells

1996 • 28 citations

1,25(OH)2-vitamin D3 mediated changes in mRNA for c-myc and 1,25(OH)2D3 receptor in HL-60 cells and related subclones

1993 • 27 citations

Vitamin D analogues: new regulators of cancer cell growth and differentiation

1993 • 14 citations

An intramolecular Diels-Alder approach to the cis ring fused isomer of the 25-hydroxy vitamin D2 Grundmann ketone

1992 • 11 citations