Comparative cytotoxicity, DNA synthesis inhibition and drug incorporation of eight anthracyclines in a model of doxorubicin-sensitive and -resistant rat glioblastoma cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Differentiated Rat Glial Cell Strain in Tissue Culture

1968 • 1,480 citations

Active outward transport of daunomycin in resistant ehrlich ascites tumor cells

1973 • 729 citations

The Anticancer Agent Adriamycin Can Be Actively Cytotoxic Without Entering Cells

1982 • 578 citations

Adriamycin—A Review

1975 • 458 citations

Doxorubicin - Anticancer Antibiotics

1981 • 402 citations

Molecular Aspects of Anti-Cancer Drug Action

1983 • 309 citations

Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones.

1986 • 231 citations

Differential formation of hydroxyl radicals by adriamycin in sensitive and resistant MCF-7 human breast tumor cells: implications for the mechanism of action

1987 • 214 citations

Daunorubicin-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell-surface P-glycoprotein.

1983 • 201 citations

4′-epi-doxorubicin, a new analogue of doxorubicin: a preliminary overview of preclinical and clinical data

1983 • 181 citations

DNA topoisomerase II: A primer on the enzyme and its unique role as a multidrug target in cancer chemotherapy

1987 • 139 citations

Membrane transport of anthracyclines

1982 • 121 citations

Tumour cell resistance to anthracyclines ? A review

1985 • 120 citations

Experimental evaluation of anthracycline analogs.

1979 • 118 citations

Rapid uptake by cultured tumor cells and intracellular behavior of 4'-O-tetrahydropyranyladriamycin.

1983 • 83 citations

Chemical and biological characterization of 4'-iodo-4'-deoxydoxorubicin.

1987 • 77 citations

Clinical pharmacology of 4-demethoxydaunorubicin (DMDR)

1986 • 45 citations

Evidence for the lack of relationship between inhibition of nucleic acid synthesis and cytotoxicity of adriamycin.

1983 • 37 citations

Clinical aspects of drug resistance.

1986 • 35 citations

Phase I trial of esorubicin (4'deoxydoxorubicin).

1984 • 27 citations

Cellular Pharmacology of Doxorubicin in Sensitive and Resistant Rat Glioblastoma Cells in Culture

1986 • 25 citations

Evidence for inhibition of growth related to compromised DNA synthesis in the interaction of daunorubicin with H-35 rat hepatoma.

1988 • 25 citations

Clinical pharmacology and toxicity of 4'-O-tetrahydropyranyladriamycin.

1987 • 25 citations

Preclinical selection of new anthracyclines.

1986 • 14 citations

Clinical pharmacology of daunorubicin in patients with acute leukemia.

1984 • 14 citations

[The role of zorubicine in the treatment of acute myeloid leukemia. Evaluation of 15 years' use].

1987 • 2 citations