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4′-epi-doxorubicin, a new analogue of doxorubicin: a preliminary overview of preclinical and clinical data

Data up to Jan 2025

Published1983
Citations181
References36

Total Citations Per Year

Abstract

References (36)

Bedside technics for the evaluation of ventricular function in man

1969 • 608 citations

Phase II evaluation of adriamycin in human neoplasia

1973 • 414 citations

Dose response evaluation of adriamycin in human neoplasia

1977 • 389 citations

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1975 • 212 citations

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1975 • 194 citations

Combination chemotherapy and adriamycin in patients with advanced breast cancer.A Southwest Oncology Group study

1976 • 151 citations

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1979 • 118 citations

Survival and response to chemotherapy for advanced colorectal adenocarcinoma. An eastern cooperative oncology group report

1980 • 117 citations

Changes of activity of daunorubicin, adriamycin and stereoisomers following the introduction or removal of hydroxyl groups in the amino sugar moiety

1977 • 83 citations

12th International Congress of Chemotherapy

1980 • 79 citations

Relationship between activity and amino sugar stereochemistry of daunorubicin and adriamycin derivatives.

1976 • 75 citations

Toxic and Therapeutic Activity of 4'-Epi-Doxorubicin

1982 • 68 citations

Controlled evaluation of adriamycin (NSC-123127) in patients with disseminated breast cancer.

1974 • 62 citations

Induction of malignant transformation and mutagenesis in cell cultures by cancer chemotherapeutic agents

1977 • 58 citations

Preliminary phase I study of 4'-epi-adriamycin.

1979 • 53 citations

Preliminary Clinical Experience with 4’-Epidoxorubicin in Advanced Human Neoplasia

1980 • 51 citations

Studies on the mode of interaction of 4'-epi-adriamycin and 4-demethoxy-daunomycin with DNA

1978 • 43 citations

Studies on the comparative distribution and biliary excretion of doxorubicin and 4'-epi-doxorubicin in mice and rats.

1980 • 38 citations

Phase II clinical evaluation of 4'-epi-doxorubicin.

1983 • 34 citations

ChemInform Abstract: SYNTHESIS AND ANTITUMOR PROPERTIES OF NEW GLYCOSIDES OF DAUNOMYCINONE AND ADRIAMYCINONE

1975 • 29 citations

Phase II clinical trial of cis dichlorodiammine platinum (Cis DDP) in metastatic brain tumors

1982 • 28 citations

Phase-II clinical trial of 4′-epi-doxorubicin in metastatic solid tumors

1983 • 28 citations

Relationship between the Effect on Calcium Turnover and Early Cardiotoxicity of Doxorubicin and 4'-EPI-Doxorubicin in Guinea Pig Heart Muscle

1980 • 27 citations

Effect of 4'-doxorubicin analogs on heterotransplantation of human tumors in congenitally athymic mice.

1981 • 24 citations

Adriamycin (NSC-123127) therapy for advanced gastrointestinal cancer.

1975 • 21 citations

A phase of I trial of 4'-epi-Adriamycin.

1981 • 20 citations

Phase II study of 4'-epi-doxorubicin in metastatic renal cancer.

1982 • 17 citations

Determination of 4′-epidoxorubicin and its 13-dihydro derivative in human plasma by high-performance liquid chromatography with fluorescence detection

1982 • 17 citations

Phase II Study of 4'Epi-Doxorubicin

1982 • 15 citations

UICC Conference on Clinical Oncology

1980 • 14 citations

Randomized phase II trial of rubidazone and adriamycin in women with advanced breast cancer.

1979 • 11 citations

Phase II trial of 5-fluorouracil, adriamycin, and mitomycin C in advanced colorectal cancer.

1978 • 9 citations

Preliminary echocardiographic and polygraphic evaluation of cardiac toxicity of 4'-epi-doxorubicin.

1983 • 9 citations

A phase II study of 4'-EPI-doxorubicin in advanced ovarian carcinoma

1982 • 9 citations

Carcinoma of renal parenchyma, renal pelvis and ureter—radiological diagnosis and treatment planning

1980 • 4 citations

Deleted Work

1955 • 0 citations

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4′-epi-doxorubicin, a new analogue of doxorubicin: a preliminary overview of preclinical… (1983) – Cancer Treatment Reviews | Metascience Observatory Explorer