Structural and functional analysis of the insulin-like growth factor I receptor gene promoter.

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

1986 • 1,866 citations

Dideoxy sequencing method using denatured plasmid templates

1986 • 1,537 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

Electroporation for the efficient transfection of mammalian cells with DNA

1987 • 856 citations

The Nature and Regulation of the Receptors for Insulin-Like Growth Factors

1985 • 639 citations

Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines.

1989 • 614 citations

Synergistic activation by the glutamine-rich domains of human transcription factor Sp1

1989 • 539 citations

Analysis of the DNA-binding and activation properties of the human transcription factor AP-2.

1991 • 519 citations

Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation.

1990 • 404 citations

Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells.

1990 • 385 citations

Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: Comparison with insulin-like growth factors I and II

1992 • 370 citations

Developmental regulation of the rat insulin-like growth factor I receptor gene.

1989 • 338 citations

Regulation by fasting of rat insulin-like growth factor I and its receptor. Effects on gene expression and binding.

1989 • 208 citations

Nuclear factor ETF specifically stimulates transcription from promoters without a TATA box

1989 • 162 citations

The type I insulin-like growth factor receptor is a motility receptor in human melanoma cells

1989 • 151 citations

Experimental Diabetes Increases Insulinlike Growth Factor I and II Receptor Concentration and Gene Expression in Kidney

1990 • 112 citations

In vitro analysis of the Antennapedia P2 promoter: identification of a new Drosophila transcription factor.

1988 • 92 citations

Analysis of the human type I insulin-like growth factor receptor promoter region

1991 • 90 citations

Characterization of the Promoter Region and 3′ End of the Human Insulin Receptor Gene

1989 • 74 citations

Progestins Induce Down-Regulation of Insulin-Like Growth Factor-I (IGF-I) Receptors in Human Breast Cancer Cells: Potential Autocrine Role of IGF-II

1991 • 58 citations

Characterization of the promoter region of the human insulin receptor gene

1989 • 46 citations

Thyroid Hormone Regulation of Transcription Factors Involved in Malic Enzyme Gene Expression

1989 • 42 citations

TPA-induced neurite formation in a neuroblastoma cell line (SH-SY5Y) is associated with increased IGF-I receptor mRNA and binding

1989 • 35 citations