Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line.

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

1987 • 814 citations

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

1986 • 686 citations

Hamster preproglucagon contains the sequence of glucagon and two related peptides

1983 • 602 citations

Truncated glucagon‐like peptide I, an insulin‐releasing hormone from the distal gut

1987 • 566 citations

Exon duplication and divergence in the human preproglucagon gene

1983 • 558 citations

Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.

1994 • 211 citations

Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic a cells

1988 • 161 citations

Parathyroid Hormone-Like Peptide in Normal and Neoplastic Human Endocrine Tissues*

1990 • 159 citations

Pre-Proglucagon Messenger Ribonucleic Acid: Nucleotide and Encoded Amino Acid Sequences of the Rat Pancreatic Complementary Deoxyribonucleic Acid*

1984 • 147 citations

Glucagon gene 5'-flanking sequences direct expression of simian virus 40 large T antigen to the intestine, producing carcinoma of the large bowel in transgenic mice.

1992 • 143 citations

Proglucagon Processing Similar to Normal Islets in Pancreatic α-Like Cell Line Derived From Transgenic Mouse Tumor

1990 • 134 citations

Proglucagon gene expression is regulated by a cyclic AMP-dependent pathway in rat intestine.

1989 • 131 citations

Structure of the human ghicagon gene

1986 • 113 citations

Cell-specific post-translational processing of preproglucagon expressed from a metallothionein-glucagon fusion gene.

1986 • 100 citations

Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells.

1990 • 88 citations

Distribution of Oxyntomodulin and Glucagon in the Gastrointestinal Tract and the Plasma of the Rat*

1987 • 88 citations

Accumulation of nonamidated preprogastrin and preprocholecystokinin products in porcine pituitary corticotrophs. Evidence of post-translational control of cell differentiation.

1986 • 84 citations

A pancreatic islet cell-specific enhancer-like element in the glucagon gene contains two domains binding distinct cellular proteins.

1990 • 82 citations

Control of Glucagon-Like Immunoreactive Peptide Secretion from Fetal Rat Intestinal Cultures*

1988 • 78 citations

Fetal Rat Intestinal Cells in Monolayer Culture: A Newin VitroSystem to Study the Glucagon-Like Immunoreactive Peptides*

1987 • 73 citations

Immunocytochemical studies suggest two pathways for enteroendocrine cell differentiation in the colon

1992 • 72 citations

Parathyroid hormone-like peptide shares features with members of the early response gene family: rapid induction by serum, growth factors, and cycloheximide.

1992 • 67 citations

Parathyroid hormone-related peptide is a downstream target for ras and src activation.

1994 • 59 citations

Pancreatic pre-proglucagons are encoded by two separate mRNAs.

1981 • 59 citations

The Rat Glucagon Gene Is Regulated by a Protein Kinase A-Dependent Pathway in Pancreatic Islet Cells*

1991 • 58 citations

Glucagon-related peptides in the human gastrointestinal mucosa

1984 • 57 citations

Developmental and Tissue-Specific Regulation of Proglucagon Gene Expression*

1990 • 54 citations

Alterations in proglucagon processing and inhibition of proglucagon gene expression in transgenic mice which contain a chimeric proglucagon-SV40 T antigen gene.

1992 • 45 citations

Proglucagon Processing in a Rat Islet Cell Line Resembles Phenotype of Intestine Rather than Pancreas*

1986 • 45 citations

Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice.

1991 • 43 citations

Transcription of the Rat Glucagon Gene by the Cyclic AMP Response Element-Binding Protein CREB Is Modulated by Adjacent CREB-Associated Proteins

1993 • 42 citations

Inhibition of pancreatic glucagon gene expression in mice bearing a subcutaneous glucagon-producing GLUTag transplantable tumor.

1992 • 38 citations

Regulation of Peptide-YY Synthesis and Secretion in Fetal Rat Intestinal Cultures*

1991 • 35 citations

Tissue-Specific Differences in the Levels of Proglucagon-Derived Peptides in Streptozotocin-Induced Diabetes*

1989 • 34 citations

Inhibition of pancreatic proglucagon gene expression in mice bearing subcutaneous endocrine tumors

1994 • 26 citations

Glucagon-Like Immunoreactive Peptides in a Rat Ileal Epithelial Cell Line (IEC-18)

1987 • 5 citations