A survey on cytosolic non-enzymic proteins involved in the metabolism of lipophilic compounds: from organic anion binders to new protein families

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Glutathione S-Transferases

1974 • 17,321 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

The Isoenzymes of Glutathione Transferase

1985 • 960 citations

Sublines of mouse 3T3 cells that accumulate lipid

1974 • 918 citations

A Binding Protein for Fatty Acids in Cytosol of Intestinal Mucosa, Liver, Myocardium, and Other Tissues

1972 • 713 citations

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

1969 • 589 citations

Ligandin: a Hepatic Protein which Binds Steroids, Bilirubin, Carcinogens and a Number of Exogenous Organic Anions

1971 • 570 citations

Microtrabecular lattice of the cytoplasmic ground substance. Artifact or reality.

1979 • 516 citations

Fatty Acid-Binding Protein in Small Intestine IDENTIFICATION, ISOLATION, AND EVIDENCE FOR ITS ROLE IN CELLULAR FATTY ACID TRANSPORT

1974 • 458 citations

[27] Glutathione S-transferases (rat and human)

1981 • 410 citations

Phospholipid exchange reactions within the liver cell

1969 • 394 citations

Exchange of Phospholipids between Liver Mitochondria and Microsomes in Vitro

1968 • 375 citations

Structural principles of the globular organization of protein chains. A stereochemical theory of globular protein secondary structure

1974 • 355 citations

Prediction of chain turns in globular proteins on a hydrophobic basis

1978 • 334 citations

Induction of lipogenesis during differentiation in a "preadipocyte" cell line.

1976 • 317 citations

Transfer of phospholipids between membrane

1974 • 314 citations

Sequence determinants of cytosolic N-terminal protein processing

1986 • 304 citations

Rat liver proteins capable of transferring phosphatidylethanolamine. Purification and transfer activity for other phospholipids and cholesterol.

1977 • 290 citations

Fatty acid binding protein. Isolation from rat liver, characterization, and immunochemical quantification.

1982 • 286 citations

Eine Cerebrosidsulfatase aus Schweineniere

1964 • 278 citations

Evidence that approximately eighty per cent of the soluble proteins from Ehrlich ascites cells are Nalpha-acetylated.

1976 • 274 citations

A radiochemical procedure for the assay of fatty acid binding by proteins

1983 • 260 citations

The binding of fatty acids to cytoplasmic proteins: Binding to Z protein in liver and other tissues of the rat

1972 • 260 citations

Some properties of phosphatidylcholine exchange protein purified from beef liver

1973 • 249 citations

Phospholipid Exchange between Membranes

1974 • 248 citations

Purification and properties of sterol carrier protein2.

1980 • 237 citations

The nucleotide sequence of rat liver fatty acid binding protein mRNA.

1983 • 235 citations

Sterol carrier protein2. Delivery of cholesterol from adrenal lipid droplets to mitochondria for pregnenolone synthesis.

1982 • 224 citations

Two nonspecific phospholipid exchange proteins from beef liver. 1. Purification and characterization

1980 • 210 citations

Function and regulation of hepatic and intestinal fatty acid binding proteins

1985 • 210 citations

Purification and Characterization of an Activator Protein for the Degradation of Glycolipids G_M2and G_A2by Hexosaminidase A

1979 • 180 citations

Developmentally regulated mRNAs in 3T3-adipocytes: analysis of transcriptional control.

1985 • 170 citations

A novel retinol-binding protein from rat. Purification and partial characterization.

1984 • 170 citations

Radioimmunochemical determination of cellular retinol- and cellular retinoic acid-binding proteins in cytosols of rat tissues.

1982 • 164 citations

Purification and characterization of a spinach-leaf protein capable of transferring phospholipids from liposomes to mitochondria or chloroplasts

1984 • 164 citations

An activator stimulating the enzymic hydrolysis of sphingoglycolipids.

1976 • 159 citations

A low-molecular-weight protein from rat liver that resembles ligandin in its binding properties

1976 • 158 citations

The participation of sterol carrier protein2 in the conversion of cholesterol to cholesterol ester by rat liver microsomes.

1981 • 154 citations

Complexing of Glycolipids and Their Transfer between Membranes by the Activator Protein for Degradation of Lysosomal Ganglioside G_M2

1982 • 152 citations

Rat liver glutathione S-transferases. Construction of a cDNA clone complementary to a Yc mRNA and prediction of the complete amino acid sequence of a Yc subunit.

1985 • 147 citations

Influence of retinoid nutritional status on cellular retinol- and cellular retinoic acid-binding protein concentrations in various rat tissues.

1985 • 145 citations

Purification and characterization of a basic 23 kDa cytosolic protein from bovine brain

1984 • 142 citations

The nucleotide sequence of a rat liver glutathione S-transferase subunit cDNA clone.

1984 • 138 citations

The Activator of Cerebroside Sulphatase. Purification from Human Liver and Identification as a Protein

1975 • 135 citations

Tissue expression of three structurally different fatty acid binding proteins from rat heart muscle, liver, and intestine

1986 • 134 citations

Purification and characterization of two phospholipid exchange proteins from bovine heart.

1979 • 125 citations

Resonance energy transfer assay of protein-mediated lipid transfer between vesicles.

1983 • 124 citations

The primary structure of bovine cellular retinoic acid-binding protein.

1985 • 124 citations

A triglyceride and cholesteryl ester transfer protein associated with liver microsomes.

1984 • 123 citations

Large scale purification and structural characterization of squalene and sterol carrier protein.

1981 • 122 citations

The complete amino acid sequence of the P2 protein in bovine peripheral nerve myelin

1980 • 122 citations

The complete nucleotide sequence for rabbit muscle aldolase A messenger RNA.

1984 • 121 citations

A protein of the Z class of liver cytosolic proteins in the rat that preferentially binds heme.

1985 • 120 citations

Purification and characterization of microsomal triglyceride and cholesteryl ester transfer protein from bovine liver microsomes

1985 • 119 citations

Specificity of the phosphatidylcholine exchange protein from bovine liver

1977 • 119 citations

Cytosolic modulators of activities of microsomal enzymes of cholesterol biosynthesis purification and characterization of a non-specific lipid-transfer protein

1983 • 119 citations

Characterization of a fatty acid-binding protein from rat heart.

1986 • 116 citations

Utilization of long chain fatty acids by rat liver: Studies of the role of fatty acid binding protein

1979 • 116 citations

Inhibition of rat liver acetyl coenzyme A carboxylase by long chain acyl coenzyme A and fatty acid. Modulation by fatty acid-binding protein.

1977 • 111 citations

Rat heart fatty acid-binding protein is highly homologous to the murine adipocyte 422 protein and the P2 protein of peripheral nerve myelin.

1986 • 111 citations

Sterol carrier protein 2 and fatty acid-binding protein. Separate and distinct physiological functions.

1985 • 109 citations

The primary structure of rat liver cellular retinol-binding protein.

1985 • 107 citations

Isolation and characterization of the three fractions (DE‐I, DE‐II and DE‐III) of rat‐liver Z‐protein and the complete primary structure of DE‐II

1983 • 107 citations

Human liver fatty acid binding protein cDNA and amino acid sequence. Functional and evolutionary implications.

1985 • 106 citations

The activator of cerebroside-sulphatase

1978 • 106 citations

Mediation of retinoic acid-induced growth and anti-tumour activity

1976 • 105 citations

Activator protein required for the enzymatic hydrolysis of cerebroside sulfate. Deficiency in urine of patients affected with cerebroside sulfatase activator deficiency and identity with activators for the enzymatic hydrolysis of GM1 ganglioside and globotriaosylceramide.

1985 • 105 citations

Newly identified bile acid binders in rat liver cytosol. Purification and comparison with glutathione S-transferases.

1983 • 104 citations

The primary structure of the human retinol‐binding protein

1979 • 100 citations

Fatty acid binding proteins from heart

1985 • 100 citations

Control of energy production in the heart: a new function for fatty acid binding protein

1985 • 99 citations

A new high-yield procedure for the purification of the non-specific phospholipid transfer protein from rat liver

1981 • 99 citations

Kinetic model of the protein-mediated phosphatidylcholine exchange between single bilayer liposomes

1975 • 98 citations

Tissue specific expression of p422 protein, a putative lipid carrier, in mouse adipocytes

1985 • 98 citations

Specificity of cellular retinol-binding protein for compounds with vitamin A activity

1975 • 96 citations

The binding of long chain fatty acid CoA to Z, a cytoplasmic protein present in liver and other tissues of the rat

1974 • 94 citations

Alteration of synaptic membrane cholesterol/phospholipid ratio using a lipid transfer protein. Effect on gamma-aminobutyric acid uptake.

1983 • 94 citations

Purification and characterization of a long chain, fatty-acid-binding protein supplying the mitochondrial β-oxidative system in the heart

1978 • 94 citations

Ligand-binding studies with a 23 kDa protein purified from bovine brain cytosol

1986 • 93 citations

Purification and properties of a soluble protein activator of rat liver squalene epoxidase.

1977 • 91 citations

Ultrastructural localization of a peroxisomal protein in rat liver using the specific antibody against the non-specific lipid transfer protein (sterol carrier protein 2)

1985 • 90 citations

Exchange of mitochondrial lecithin and cephalin with those in rat liver microsomes

1969 • 90 citations

Purification and characterization of fatty acid-binding proteins from rat heart and liver

1985 • 89 citations

Fatty acid transfer between multilamellar liposomes and fatty acid-binding proteins.

1984 • 88 citations

Cytosolic modulators of activities of microsomal enzyme of cholesterol biosynthesis. Role of a cytosolic protein with properties similar to Z-protein (fatty acid-binding protein).

1980 • 88 citations

Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins.

1985 • 87 citations

Phospholipid transfer in yeast. Isolation and partial characterization of a phospholipid transfer protein from yeast cytosol

1984 • 87 citations

The activator of cerebroside sulphatase binding studies with enzyme and substrate demonstrating the detergent function of the activator protein

1977 • 87 citations

Purification and properties of sterol carrier protein1.

1976 • 87 citations

Sterol carrier and lipid transfer proteins

1985 • 84 citations

Complete amino acid sequence of a basic 21-kDa protein from bovine brain cytosol

1987 • 84 citations

Modulation of membrane transport by free fatty acids: inhibition of synaptosomal sodium-dependent amino acid uptake

1983 • 84 citations

A protein activator for the enzymic hydrolysis of GM2 ganglioside.

1981 • 83 citations

The primary structure of the nonspecific lipid transfer protein (sterol carrier protein 2) from bovine liver

1985 • 81 citations

Cellular retinol-binding protein. Quantitation and distribution.

1984 • 81 citations

Bovine fatty acid binding proteins

1985 • 80 citations

Stimulation of triacylglycerol synthesis by Z protein in rat liver and intestinal mucosa

1975 • 80 citations

A receptor for retinol in the developing retina and pigment epithelium

1975 • 79 citations

Z protein: Isolation and characterization of multiple forms in rat liver cytosol

1981 • 78 citations

Determination of nonspecific lipid transfer protein in rat tissues and morris hepatomas by enzyme immunoassay

1984 • 78 citations

A close structural relationship of rat liver Z-protein to cellular retinoid binding proteins and peripheral nerve myellin P2 protein

1982 • 77 citations

11-cis-Retinal-binding protein from bovine retina. Isolation and partial characterization.

1979 • 75 citations

The Complete Primary Structure of the Phosphatidylcholine-Transfer Protein from Bovine Liver. Isolation and Characterization of the Cyanogen Bromide Peptides

1981 • 74 citations

Fatty acid binding protein from rat heart. The fatty acid binding proteins from rat heart and liver are different proteins.

1984 • 73 citations

Evolution of serum albumin

1977 • 73 citations

The Protein Activator Specific for the Enzymic Hydrolysis of GM₂ Ganglioside in Normal Human Brain and Brains of Three Types of GM₂ Gangliosidosis

1983 • 72 citations

Purification of a basic phospholipid transfer protein from maize seedlings

1982 • 72 citations

Properties of a specific glycolipid transfer protein from bovine brain

1985 • 70 citations

Primary structure of rat liver Z‐protein

1982 • 66 citations

Self-association of the cardiac fatty acid binding protein. Influence on membrane-bound, fatty acid dependent enzymes

1983 • 66 citations

Partial purification of molecular-weight-12,000 fatty acid-binding proteins from rat brain and their effect on synaptosomal sodium-dependent amino acid uptake

1984 • 65 citations

Analyzing the structures, functions and evolution of two abundant gastrointestinal fatty acid binding proteins with recombinant DNA and computational techniques

1985 • 65 citations

Phospholipid transfer activities in morris hepatomas and the specific contribution of the phosphatidylcholine exchange protein

1980 • 65 citations

Increased cholesterol esterification in rat liver microsomes by purified non-specific phospholipid transfer protein

1982 • 65 citations

Purification and properties of a cerebroside transfer protein.

1982 • 64 citations

Studies on the subunit composition of rat liver glutathione S-transferases.

1983 • 64 citations

Supernatant protein factor facilitates intermembrane transfer of squalene.

1980 • 63 citations

A subclass of glutathione S-transferases as intracellular high-capacity and high-affinity steroid-binding proteins

1986 • 63 citations

Sterol and squalene carrier protein interactions with fluorescent delta 5,7,9(11)-cholestatrien-3 beta-ol.

1985 • 62 citations

The amino-acid sequence of the nonspecific lipid transfer protein from germinated castor bean endosperms

1986 • 62 citations

The Yc and Ya subunits of rat liver glutathione S-transferases are the products of separate genes.

1984 • 61 citations

Pathophysiology of the enterohepatic circulation of bile acids

1979 • 61 citations

On the multiplicity of rat liver glutathione S-transferases.

1985 • 60 citations

Isolation and amino acid analysis of a nonspecific phospholipid transfer protein from rat liver

1978 • 58 citations

The Complete Amino Acid Sequence of Human P2 Protein

1982 • 57 citations

Purification and characterization of a non-specific lipid transfer protein from germinated castor bean endosperms which transfers phospholipids and galactolipids

1986 • 55 citations

Glycolipid transfer protein from bovine brain

1984 • 55 citations

Phospholipid transfer proteins in rat lung. Identification of a protein specific for phosphatidylglycerol.

1980 • 55 citations

Net transfer of phospholipid by the nonspecific phospholipid transfer proteins from bovine liver

1980 • 55 citations

The complete amino acid sequence of the rabbit P2 protein.

1982 • 54 citations

Enzymatic Conversion of Squalene to Cholesterol by an Acetone Powder of Rat Liver Microsomes

1968 • 54 citations

Phosphatidylcholine exchange protein catalyzes the net transfer of phosphatidylcholine to model membranes

1980 • 53 citations

The non-specific lipid transfer protein (sterol carrier protein 2) from rat and bovine liver

1985 • 53 citations

Hepatic lipid metabolism: Effect of spermine, albumin, and Z protein on microsomal lipid formation

1979 • 53 citations

Determination of the Hydrophobic Binding Site of Phosphatidylcholine Exchange Protein with Photosensitive Phosphatidylcholine

1979 • 51 citations

A protein purified from pig brain accelerates the intermembranous translocation of mono- and dihexosylceramides, but not the translocation of phospholipids

1982 • 51 citations

Phosphatidylinositol transfer proteins: Structure, catalytic activity, and physiological function

1985 • 49 citations

Cellular retinoid binding proteins

1985 • 49 citations

Activator protein for the degradation of globotriaosylceramide by human alpha-galactosidase.

1983 • 48 citations

Biochemical, immunological, and structural studies on a sphingolipid activator protein (SAP-1)

1984 • 47 citations

Intermembrane transfer of 5 alpha-cholest-7-en-3 beta-ol. Facilitation by supernatant protein (SCP).

1981 • 47 citations

The interactions of haem with ligandin and aminoazo-dye-binding protein A.

1976 • 47 citations

Acetylated N-terminals in proteins — a perennial enigma

1984 • 46 citations

Ovalbumin utilizes an NH2-terminal signal sequence.

1982 • 45 citations

Specificity of the glycolipid transfer protein from pig brain.

1985 • 45 citations

Identification of the Lipid-Binding Site of Phosphatidylcholine-Transfer Protein with Phosphatidylcholine Analogs Containing Photactivable Carbene Precursors

1983 • 45 citations

Lipid-binding proteins in plants

1985 • 44 citations

Cytosolic rat liver glutathione transferase 4-4. Primary structure of the protein reveals extensive differences between homologous glutathione transferases of classes Alpha and Mu

1986 • 44 citations

Translational control of the circadian rhythm of liver sterol carrier protein.

1984 • 43 citations

Rapid methods for the characterization of unilamellar phospholipid vesicles. Application to studies on fatty acid donor and acceptor properties of membranes and fatty acid binding proteins

1984 • 43 citations

N‐terminal sequence homology among retinoid‐binding proteins from bovine retina

1981 • 42 citations

Spectroscopic investigations on the binding site of bovine hepatic fatty acid binding protein. Evidence for the existence of a single binding site for two fatty acid molecules

1985 • 42 citations

Purification and some properties of the glycolipid transfer protein from pig brain.

1985 • 42 citations

A unique phosphatidylcholine exchange protein isolated from sheep lung

1978 • 39 citations

Self-aggregation, a new property of cardiac fatty acid-binding protein. Predictable influence on energy production in the heart.

1983 • 38 citations

The synthesis and esterification of cholesterol by hepatocytes and H35 hepatoma cells are independent of the level of nonspecific lipid transfer protein

1985 • 38 citations

Purification and binding characteristics of a basic fatty acid binding protein from Avena sativa seedlings

1984 • 36 citations

Vitamin A receptors. Retinoic acid binding in ocular tissues

1978 • 35 citations

Identification and purification of a 36 kDa bile acid binder in human hepatic cytosol

1984 • 35 citations

A phospholipid transfer protein that binds long‐chain fatty acids

1985 • 34 citations

Circular dichroism analysis of the secondary structure of Z protein and its complexes with bilirubin and other organic anions

1975 • 33 citations

Crystallization of and preliminary X-ray data for an intracellular vitamin A-binding protein from rat liver.

1981 • 33 citations

Purification and characterization of a phosphatidylinositol transfer protein from human platelets

1985 • 32 citations

Newly identified organic anion-binding proteins in rat liver cytosol

1982 • 30 citations

Prediction of Secondary Structura1 Elements in the Phosphatidylcholine–Transfer Protein from Bovine Liver

1982 • 29 citations

Net mass transfer of galactosylceramide facilatated by glycolipid transfer protein from pig brain: a monolayer study

1985 • 29 citations

Purification and properties of a phospholipid transfer protein from Rhodopseudomonas sphaeroides.

1984 • 29 citations

Cellular fructose-P2 aldolase has a derivatized (blocked) NH2 terminus.

1984 • 28 citations

A rat brain cytosol protein which accelerates the translocation of galactosylceramide, lactosylceramide and glucosylceramide between membranes

1982 • 28 citations

Isolation and Characterization of an Unsaturated Fatty Acid‐Binding Protein from Developing Chick Neural Retina

1984 • 28 citations

Activation of lysosomal hydrolysis of complex glycolipids by non-enzymic proteins

1979 • 27 citations

A fluorimetric determination of the activity of glycolipid transfer protein and some properties of the protein purified from pig brain

1984 • 26 citations

Properties of a protein activator of glycosphingolipid hydrolysis isolated from the liver of a patient with GM1 gangliosidosis, Type 1

1982 • 26 citations

Acyl chain specificity of phosphatidylcholine transfer protein from bovine liver.

1984 • 25 citations

Properties of a non-specific phospholipid-transfer protein purified from rat lung

1983 • 25 citations

Protein-facilitated intermembrane transfer of squalene. Demonstration by density gradient centrifugation.

1981 • 25 citations

Phospholipid-exchange proteins: a new class of intracellular lipoproteins

1977 • 24 citations

PREDICTION OF PROTEIN CONFORMATION FROM THE PRIMARY STRUCTURE *

1980 • 24 citations

The metabolic sequence by which some 4,4-dimethyl sterols are converted into cholesterol

1974 • 23 citations

Glycolipid-binding proteins

1985 • 23 citations

Specific binding of saturated and unsaturated fatty acids on the ‘Z’‐protein of rat liver cytosol

1978 • 22 citations

Studies on ligand binding properties of Z-fraction from rat liver cytosol using 1-anilino-8-naphthalenesulfonate.

1978 • 20 citations

A General Model of the P₂ Protein of Peripheral Nervous System Myelin Based on Secondary Structure Predictions, Tertiary Folding Principles, and Experimental Observations

1983 • 20 citations

X‐ray studies on triclinic crystals of fatty acid binding protein

1985 • 19 citations

Studies on the mode of action of sterol carrier protein in the dehydrogenation of 5-cholest-7-en-3 beta-ol.

1985 • 18 citations

Phospholipid transfer proteins in microorganisms

1985 • 18 citations

What is the cytosol?

1983 • 18 citations

Purification and properties of retinol- and retinoic acid-binding proteins from a transplantable mouse colon tumor

1980 • 17 citations

The inactivity of brain phospholipid transfer protein toward phosphatidylinositol 4-phosphate

1983 • 17 citations

Serum albumin stimulation of synaptosomal proline uptake: Partial identification of the active site

1978 • 17 citations

Role of sterol carrier protein in cholesterol metabolism

1985 • 16 citations

Translational control of the circadian rhythm of liver sterol carrier protein. Analysis of mRNA sequences with a specific cDNA probe.

1985 • 16 citations

Phospholipids, sterol carrier protein 2 and adrenal steroidogenesis

1985 • 16 citations

Phospholipid transfer proteins from lung, properties and possible physiological functions

1985 • 14 citations

Purification of liver cytosolic proteins that stimulate triacylglycerol synthesis

1981 • 13 citations

Binding protein for 1-anilino-8-naphthalenesulfonate in rat liver cytoplasm

1980 • 11 citations

The lipid binding site of the phosphatidylcholine transfer protein from bovine liver

1985 • 11 citations

Identification of an essential lysine residue in the phosphatidylcholine-transfer protein from bovine liver by modification with phenylisothiocyanate

1986 • 10 citations

Bovine brain phosphatidylinositol transfer protein. Selective inhibition by chlorpromazine and other amphiphilic amines.

1984 • 10 citations

Amino-terminal amino acid sequence of the nonspecific phospholipid exchange protein from bovine liver

1984 • 9 citations

The phosphatidylcholine transfer protein from bovine liver discriminates between phosphatidylcholine isomers. A monolayer study

1986 • 8 citations

Purification of bile acid-binding proteins from rat hepatic cytosol. Use of a photoaffinity label to detect novel Y′ binders

1986 • 8 citations

Purification and characterization of protein Z from rabbit liver cytosol

1985 • 5 citations