Thrombophilia, Clinical Factors, and Recurrent Venous Thrombotic Events

Mutation in blood coagulation factor V associated with resistance to activated protein C

1994 • 3,871 citations

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

1996 • 3,124 citations

The Long-Term Clinical Course of Acute Deep Venous Thrombosis

1996 • 2,090 citations

A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study

1991 • 1,994 citations

Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study

1993 • 1,283 citations

Role of clotting factor VIII in effect of von Willebrand factor on occurrence of deep-vein thrombosis

1995 • 1,117 citations

A Comparison of Three Months of Anticoagulation with Extended Anticoagulation for a First Episode of Idiopathic Venous Thromboembolism

1999 • 1,076 citations

High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance) [see comments]

1995 • 1,036 citations

Hyperhomocysteinemia as a Risk Factor for Deep-Vein Thrombosis

1996 • 1,034 citations

A prospective study of the incidence of deep‐vein thrombosis within a defined urban population

1992 • 799 citations

Incidence of venous thromboembolism: a community-based study in Western France. EPI-GETBP Study Group. Groupe d'Etude de la Thrombose de Bretagne Occidentale.

2000 • 777 citations

High Plasma Levels of Factor VIII and the Risk of Recurrent Venous Thromboembolism

2000 • 741 citations

Incidence of recurrent venous thromboembolism in relation to clinical and thrombophilic risk factors: prospective cohort study

2003 • 695 citations

High Levels of Coagulation Factor XI as a Risk Factor for Venous Thrombosis

2000 • 670 citations

Recurrent Venous Thromboembolism After Deep Vein Thrombosis

2000 • 590 citations

Residual Venous Thrombosis as a Predictive Factor of Recurrent Venous Thromboembolism

2002 • 535 citations

The Risk of Recurrent Deep Venous Thrombosis among Heterozygous Carriers of Both Factor V Leiden and the G20210A Prothrombin Mutation

1999 • 483 citations

The Risk of Recurrent Venous Thromboembolism in Men and Women

2004 • 471 citations

Risk Factors for Venous Thrombotic Disease

1999 • 380 citations

The Risk of Recurrent Venous Thromboembolism in Patients with an Arg⁵⁰⁶→Gln Mutation in the Gene for Factor V (Factor V Leiden)

1997 • 380 citations

Is hyperhomocysteinaemia a risk factor for recurrent venous thrombosis?

1995 • 374 citations

Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study) [see comments]

1995 • 372 citations

High levels of factor IX increase the risk of venous thrombosis

2000 • 364 citations

Factor VII and Fibrinogen Levels as Risk Factors for Venous Thrombosis

1994 • 294 citations

The Leiden Thrombophilia Study (LETS)

1997 • 280 citations

Factor V Leiden and Risks of Recurrent Idiopathic Venous Thromboembolism

1995 • 251 citations

Hyperhomocysteinemia is a risk factor of recurrent venous thromboembolism.

1998 • 225 citations

The diagnosis of acute, recurrent, deep-vein thrombosis: a diagnostic challenge.

1983 • 219 citations

The Risk of Recurrent Venous Thromboembolism in Carriers and Non-carriers of the G1691A Allele in the Coagulation Factor V Gene and the G20210A Allele in the Prothrombin Gene

1999 • 217 citations

The Risk of Recurrent Venous Thromboembolism in Patients with and without Factor V Leiden

1997 • 206 citations

The Risk of Early Recurrent Venous Thromboembolism after Oral Anticoagulant Therapy in Patients with the G20210A Transition in the Prothrombin Gene

1999 • 135 citations

High risk of recurrent venous thromboembolism in men

2004 • 129 citations

Risk for subsequent venous thromboembolic complications in carriers of the prothrombin or the factor V gene mutation with a first episode of deep-vein thrombosis

2000 • 128 citations

The risk of recurrent venous thromboembolism among patients with high factor IX levels

2003 • 96 citations

Probability of Recurrence of Thrombosis in Patients with and without Factor V Leiden

1996 • 92 citations

G20210A mutation in the prothrombin gene and the risk of recurrent venous thromboembolism

2001 • 89 citations

The risk of recurrent venous thromboembolism among heterozygous carriers of the G20210A prothrombin gene mutation

2001 • 88 citations

The Risk of Recurrent Venous Thromboembolism in Heterozygous Carriers of Factor V Leiden and a First Spontaneous Venous Thromboembolism

2002 • 82 citations

Recurrent Deep Vein Thrombosis and Two Coagulation Factor Gene Mutations: Quo Vadis?

1999 • 25 citations

Deleted Work

1955 • 0 citations