Studies on the Role of Lymphocyte Function‐Associated Antigen 1 (LFA‐1) in T Cell Activation

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain

1959 • 2,294 citations

Monoclonal Antibodies Defining Distinctive Human T Cell Surface Antigens

1979 • 1,480 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

1981 • 1,366 citations

There is more than one interleukin 1

1986 • 1,226 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

T cell growth factor receptors. Quantitation, specificity, and biological relevance

1981 • 1,087 citations

T‐Cell Growth Factor

1980 • 917 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

Protein a from Staphylococcus aureus. Its isolation by affinity chromatography and its use as an immunosorbent for isolation of immunoglobulins

1972 • 607 citations

Interleukin 1: An Immunological Perspective

1985 • 576 citations

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

1980 • 525 citations

Cloning of the $beta; subunit of the leukocyte adhesion proteins: Homology to an extracellular matrix receptor defines a novel supergene family

1987 • 520 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester.

1986 • 487 citations

Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

1983 • 464 citations

Transferrin receptor induction in mitogen-stimulated human T lymphocytes is required for DNA synthesis and cell division and is regulated by interleukin 2.

1983 • 448 citations

Interleukin 2 regulates its own receptors.

1985 • 414 citations

Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro.

1982 • 335 citations

A human lymphocyte‐associated antigen involved in cell‐mediated lympholysis

1983 • 315 citations

Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression.

1985 • 311 citations

Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?

1981 • 306 citations

Definition of a common leukocyte cell-surface antigen (Lp95-150) associated with diverse cell-mediated immune functions.

1983 • 305 citations

Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions.

1981 • 292 citations

Human melanoma-associated antigen p97 is structurally and functionally related to transferrin

1982 • 288 citations

Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.

1985 • 280 citations

THE CATABOLISM OF HOMOLOGOUS AND HETEROLOGOUS 7S GAMMA GLOBULIN FRAGMENTS

1965 • 235 citations

cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors.

1986 • 231 citations

Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen.

1984 • 227 citations

LFA-1, LFA-2, and LFA-3 antigens are involved in CTL-target conjugation.

1984 • 227 citations

LFA‐1 and Lyt‐2,3, Molecules Associated with T Lymphocyte‐Mediated Killing; and Mac‐1, an LFA‐1 Homologue Associated with Complement Receptor Function¹

1982 • 223 citations

The primary structure of the beta-subunit of the cell surface adhesion glycoproteins LFA-1, CR3 and p150,95 and its relationship to the fibronectin receptor.

1987 • 215 citations

Fc receptors for mouse IgG1 on human monocytes: polymorphism and role in antibody-induced T cell proliferation.

1984 • 164 citations

Biochemical and functional characteristics of the human leukocyte membrane antigen family LFA‐1, Mo‐1 and p!50,95

1985 • 162 citations

Human T cell activation. I. Monocyte-independent activation and proliferation induced by anti-T3 monoclonal antibodies in the presence of tumor promoter 12-o-tetradecanoyl phorbol-13 acetate.

1985 • 155 citations

Characterization of Monoclonal Antibodies Against Cell Surface Molecules Associated with Cytotoxic Activity of Natural and Activated Killer Cells and Cloned CTL Lines

1983 • 155 citations

Purification, Fractionation and Assay of Antibody‐Dependent Lymphocytic Effector Cells (K Cells) in Human Blood

1976 • 146 citations

Identification of a Cell Surface Protein Complex Mediating Phorbol Ester‐Induced Adhesion (Binding) among Human Mononuclear Leukocytes

1985 • 139 citations

Mechanisms by which accessory cells contribute in growth of resting T lymphocytes initiated by OKT3 antibody

1985 • 126 citations

A new subunit of the human T-cell antigen receptor complex

1986 • 108 citations

Cyclosporin A does not prevent expression of Tac antigen, a probable TCGF receptor molecule, on mitogen-stimulated human T cells.

1983 • 105 citations

LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes.

1985 • 93 citations

The two-chain structure of high-affinity IL-2 receptors

1987 • 93 citations

Helix pomatia A hemagglutinin: selectivity of binding to lymphocyte surface glycoproteins on T cells and certain B cells

1978 • 86 citations

Human gamma interferon production by leukocytes induced with monoclonal antibodies recognizing T cells.

1981 • 85 citations

Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity.

1983 • 75 citations

Effects of monoclonal antibodies to the a and β chains of the human lymphocyte function‐associated (H‐LFA‐1) antigen on T lymphocyte functions

1985 • 53 citations

Identification of 5 topographic domains of the mouse LFA-1 molecule: subunit assignment and functional involvement in lymphoid cell interactions.

1986 • 44 citations

Functional distinctions between the LFA-1, LFA-2, and LFA-3 membrane proteins on human CTL are revealed with trypsin-pretreated target cells.

1985 • 27 citations

Antibody Dependent Cellular Cytotoxicity and Mitogen Responsiveness of Human Peripheral Blood Lymphocytes Differing in Avidity for Sheep Erythrocytes

1979 • 24 citations

Analysis of T cell activation with a non-mitogenic anti CD3 antibody and the phorbol ester TPA.

1985 • 24 citations

Blocking of CTL-mediated killing by monoclonal antibodies to LFA-1 and Lyt-2, 3. II. Evidence that trypsin pretreatment of target cells removes a non-H-2 molecule important in killing.

1985 • 22 citations

Transferrin Receptors on Mitogen‐Stimulated Human Thymus‐Derived Lymphocytes

1982 • 19 citations

Activation and growth requirements for cytotoxic and noncytotoxic T lymphocytes

1984 • 17 citations

The Mode of Action of the Calcium Ionophore A23187 on T Cell Proliferation.

1985 • 13 citations

Inhibition of proliferative and cytotoxic activities of human T lymphocytes with rabbit antibodies directed against leucoagglutinin‐reactive T cell surface components

1984 • 13 citations

A monoclonal antibody inhibiting leucocyte adhesion blocks induction of IL-2 production but not IL-2 receptor expression.

1987 • 12 citations

The use of supernatants from neuraminidase and galactose oxidase (NAGO)-treated lymphocytes as a source of T cell growth factor

1983 • 7 citations