Relative abuse liability of triazolam: Experimental assessment in animals and humans

Problems of Drug Dependence

1969 • 970 citations

Self-administration of psychoactive substances by the monkey

1969 • 807 citations

Measurement of Subjective Responses: Quantitative Effects of Drugs

1960 • 491 citations

Stimulus properties of drugs : ten years of progress

1978 • 402 citations

Withdrawal from long-term benzodiazepine treatment.

1981 • 368 citations

Clinical Pharmacokinetics of Oxazepam and Lorazepam

1981 • 362 citations

Withdrawal reactions from chlordiazepoxide (?Librium?)

1961 • 340 citations

BENZODIAZEPINE WITHDRAWAL SYMPTOMS AND PROPRANOLOL

1981 • 298 citations

FIXED‐INTERVAL SCHEDULE OF COCAINE REINFORCEMENT: EFFECT OF DOSE AND INFUSION DURATION¹

1973 • 293 citations

Benzodiazepine withdrawal: an unfinished story.

1984 • 289 citations

Benzodiazepine Dependence A Review of the Evidence

1983 • 288 citations

GRADUAL WITHDRAWAL OF DIAZEPAM AFTER LONG-TERM THERAPY

1983 • 270 citations

Rebound Insomnia: A New Clinical Syndrome

1978 • 201 citations

Assessment of the Abuse Potentiality of Morphinelike Drugs (Methods Used in Man)

1977 • 201 citations

Rebound Insomnia and Rebound Anxiety: A Review

1983 • 198 citations

Predicting the Abuse Liability of Drugs with Animal Drug Self-Administration Procedures: Psychomotor Stimulants and Hallucinogens

1979 • 190 citations

Chemical Protection against Ionizing Radiation: I. Sampling Methods for Screening Compounds in Radiation Protection Studies with Mice

1957 • 186 citations

Evaluation and Treatment of Insomnia

1987 • 171 citations

Predicting dependence liability of stimulant and depressant drugs

1977 • 169 citations

Cocaine self-administration in humans.

1982 • 169 citations

BENZODIAZEPINES: USE, OVERUSE, MISUSE, ABUSE?

1973 • 167 citations

Comparison of the degree of discriminability of various drugs using the T-maze drug discrimination paradigm

1982 • 166 citations

Stereoisomers of N -Allylnormetazocine: Phencyclidine-Like Behavioral Effects in Squirrel Monkeys and Rats

1982 • 165 citations

Withdrawal Reaction From Long-term, Low-dosage Administration of Diazepam

1980 • 158 citations

Precipitated Withdrawal by a Benzodiazepine Receptor Antagonist (Ro 15-1788) After 7 Days of Diazepam

1982 • 154 citations

Kinetics and clinical effects of flurazepam in young and elderly noninsomniacs

1981 • 153 citations

Reinforcement Properties of Morphine, Cocaine, and SPA as a Function of Unit Dose

1968 • 150 citations

Dependence liability of several sedative-hypnotic agents evaluated in monkeys.

1973 • 141 citations

Triazolam disposition

1981 • 140 citations

Early Morning Insomnia with Rapidly Eliminated Benzodiazepines

1983 • 139 citations

The effects of flurazepam, lorazepam, and triazolam on sleep and memory

1980 • 135 citations

Acute overdosage with benzodiazepine derivatives

1977 • 134 citations

Daytime Carryover of Triazolam and Flurazepam in Elderly Insomniacs

1982 • 129 citations

Diazepam and Drug-Associated Deaths

1979 • 128 citations

Clinical Pharmacokinetics of the Newer Benzodiazepines

1983 • 128 citations

Opioids: Similarity between evaluations of subjective effects and animal self-administration results

1979 • 127 citations

Evaluation and Treatment of Insomnia.

1984 • 124 citations

Drug preference in humans: double-blind choice comparison of pentobarbital, diazepam and placebo.

1980 • 116 citations

Discriminative stimulus properties of benzodiazepines, barbiturates and pharmacologically related drugs; Relation to some intrinsic and anticonvulsant effects

1976 • 115 citations

Self-injection of barbiturates and benzodiazepines in baboons

1981 • 106 citations

Behavioral Pharmacology of Human Drug Dependence

1981 • 105 citations

An experimental framework for evaluation of dependence liability of various types of drugs in monkeys.

1973 • 101 citations

Effects of triazolam (0.5 mg) on sleep, performance, memory, and arousal threshold

1982 • 101 citations

Internal stimulus control and subjective effects of drugs.

1981 • 100 citations

Hypnotic Efficacy of Triazolam: Sleep Laboratory Evaluation of Intermediate‐Term Effectiveness

1976 • 99 citations

Comparative Hypnotic Effects of Flurazepam, Triazolam, and Placebo

1984 • 99 citations

Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo.

1979 • 98 citations

Use of the specific benzodiazepine antagonist, Ro 15-1788, in studies of physiological dependence on benzodiazepines

1982 • 96 citations

Precipitated diazepam withdrawal in baboons: Effects of dose and duration of diazepam exposure

1984 • 95 citations

LIABILITY OF ADDICTION TO 6-DIMETHYLAMINO-4-4-DIPHENYL-3-HEPTANONE (METHADON, "AMIDONE" OR "10820") IN MAN

1948 • 95 citations

Differential Actions of Chlordiazepoxide and Oxazepam on Hostility

1968 • 91 citations

Differential Effects of Diazepam and Pentobarbital on Mood and Behavior

1983 • 91 citations

Chlordiazepoxide-Induced Hostility in a Small Group Setting

1974 • 91 citations

Discriminative stimulus effects of diazepam in rats: evidence for a maximal effect.

1983 • 91 citations

Abrupt Withdrawal From Therapeutically Administered Diazepam

1978 • 90 citations

Comparison of diazepam and oxazepam: preference, liking and extent of abuse.

1984 • 88 citations

Withdrawal Phenomena after Long-term Administration of Benzodiazepines A Review of Recent Investigations

1983 • 85 citations

Behavior maintained under a second-order schedule by intramuscular injection of morphine or cocaine in rhesus monkeys.

1976 • 84 citations

Relative abuse liability of diazepam and oxazepam: Behavioral and subjective dose effects

1984 • 81 citations

The Benzodiazepines: Use, Overuse, Misuse, Abuse

1978 • 80 citations

Psychotropic drug side effects : clinical and theoretical perspectives

1970 • 79 citations

Comparative Effectiveness of Nine Hypnotic Drugs: Sleep Laboratory Studies

1977 • 79 citations

Drug preference and mood in humans: Repeated assessment of d-amphetamine

1981 • 75 citations

Effects of Hypnotics on Memory

1983 • 75 citations

The effect of triazolam on the sleep of insomniacs

1975 • 73 citations

Lorazepam and pentobarbital drug discrimination in baboons: cross-drug generalization and interaction with Ro 15-1788.

1983 • 73 citations

Demonstration of tolerance to and physical dependence of N-allylnormorphine (nalorphine).

1965 • 73 citations

A comparison of the effects of flurazepam 30 mg and triazolam 0.5 mg on the sleep of insomniacs

1976 • 72 citations

A Pilot Study of Occasional Heroin Users

1973 • 72 citations

Effects of loprazolam and of triazolam on sleep and overnight urinary cortisol

1984 • 71 citations

Diazepam and pentobarbital dependence in the rat

1982 • 68 citations

The effect of a benzodiazepine antagonist, R015-1788, in diazepam dependent rats

1982 • 66 citations

Abuse potential of halazepam and of diazepam in patients recently treated for acute alcohol withdrawal

1983 • 66 citations

Quazepam and flurazepam: Long-term use and extended withdrawal

1982 • 63 citations

Activity of the hypnotics, flunitrazepam and triazolam, in man.

1980 • 63 citations

Reinforcing properties of stereoisomers of the putative sigma agonists N-allylnormetazocine and cyclazocine in rhesus monkeys.

1983 • 62 citations

Intermediate Use of Triazolam: A Sleep Laboratory Study

1976 • 60 citations

Psychopharmacologic treatment of anxiety.

1983 • 59 citations

Drinking device for rhesus monkeys

1976 • 59 citations

Adverse Effects of Antianxiety Drugs

1981 • 58 citations

Classification of narcotics on the basis of their reinforcing, discriminative, and antagonist effects in rhesus monkeys.

1982 • 54 citations

THE HALCION STORY: TRIAL BY MEDIA

1980 • 52 citations

Daytime Sleepiness as a Criterion in Hypnotic Medication Trials: Comparison of Triazolam and Flurazepam

1983 • 51 citations

The Need to Redefine Addiction

1983 • 50 citations

Rebound Insomnia and Elimination Half‐Life: Assessment of Individual Subject Response

1985 • 49 citations

The differential effects of chlordiazepoxide and oxazepam on hostility in a small group setting

1975 • 48 citations

Ethanol drinking by rhesus monkeys with concurrent access to water

1979 • 47 citations

A Study of Illicit Amphetamine Drug Traffic in Oklahoma City

1966 • 47 citations

Pharmacology and Hypnotic Efficacy of Triazolam

1983 • 47 citations

An antagonist-induced benzodiazepine abstinence syndrome

1982 • 46 citations

Precipitated and spontaneous withdrawal in baboons after chronic dosing with lorazepam and CGS 9896

1984 • 45 citations

A Comparative 25‐Night Sleep Laboratory Study on the Effects of Quazepam and Triazolam on Chronic Insomniacs

1984 • 45 citations

Identification and management of benzodiazepine dependence.

1984 • 43 citations

Triazolam and anterograde amnesia: all is not well in the Z-zone.

1983 • 42 citations

Effects of clorazepate, diazepam, lorazepam, and placebo on human memory.

1983 • 41 citations

Kinetics of five benzodiazepine hypnotics in healthy subjects

1983 • 41 citations

Benzodiazepine self-administration in animals and humans: a comprehensive literature review.

1980 • 39 citations

Human sedative self-administration: effects of interingestion interval and dose.

1976 • 39 citations

Onset of peak impairment after diazepam and after alcohol

1981 • 39 citations

ORAL PREMEDICATION WITH LORAZEPAM (ATIVAN): A COMPARISON WITH HEPTABARBITONE (MEDOMIN) AND DIAZEPAM (VALIUM)

1973 • 37 citations

Establishment and maintenance of oral ethanol self-administration in the baboon

1981 • 36 citations

Abuse Liability of Benzodiazepines:A Review of Human Studies Evaluating Subjective and/or Reinforcing Effects

1985 • 35 citations

A Clinical Study or Flurazepam

1982 • 33 citations

Differential amnestic properties of short- and long-acting benzodiazepines.

1984 • 32 citations

Triazolam and Anterograde Amnesia

1983 • 32 citations

Lorazepam and pentobarbital discrimination: Interactions with CGS 8216 and caffeine

1985 • 32 citations

Triazolam concentration-effect relationships in healthy subjects

1983 • 31 citations

Human progressive-ratio performance: Maintenance by pentobarbital

1983 • 31 citations

Adverse reactions to triazolam, flurazepam, and placebo in controlled clinical trials.

1984 • 30 citations

CLINICAL CONTRIBUTION TO DRUG ADDICTION

1927 • 30 citations

Orally delivered pentobarbital as a reinforcer for rhesus monkeys with concurrent access to water: Effects of concentration, fixed-ratio size, and liquid positions

1982 • 25 citations

Early morning insomnia, daytime anxiety, and organic mental disorder associated with triazolam.

1985 • 25 citations

Studies on the Dependence-Inducing Potential of Zopiclone and Triazolam

1983 • 23 citations

Diazepam and drug-associated deaths. A survey in the United States and Canada

1979 • 22 citations

Effects of Chlordiazepoxide and Oxazepam Administration on Verbal Hostility

1977 • 21 citations

Comparison of the Reinforcing Properties of Zopiclone and Triazolam in Former Alcoholics

1983 • 21 citations

Methods of Assessing the Reinforcing Properties of Abused Drugs

1989 • 20 citations

Pharmacokinetic Noninteraction of Triazolam and Ethanol

1984 • 19 citations

Hallucinations from Triazolam

1980 • 19 citations

Hypnotics and anxiolytics.

1983 • 19 citations

Oral self-administration of methohexital in baboons

1983 • 18 citations

Effects of clorazepate, diazepam, lorazepam, and placebo on human memory

1984 • 17 citations

Triazolam Psychosis—A Syndrome?

1982 • 15 citations

A comparison of two benzodiazepine hypnotics administered with alcohol.

1982 • 15 citations

Pharmacology and Pharmacokinetics of the Minor Tranquilizers

1981 • 15 citations

Dependence-Producing Effects of Anxiolytics

1981 • 14 citations

A COMPARISON OF LORAZEPAM AND DIAZEPAM AS ORAL PREMEDICANTS FOR SURGERY UNDER REGIONAL ANAESTHESIA

1974 • 13 citations

The van der Kroef syndrome

1980 • 13 citations

TRIALS AND TRIBULATIONS OF TRIAZOLAM

1980 • 12 citations

Mass hysteria among schoolchildren

1983 • 11 citations

Mortality and medicine.

1982 • 10 citations

Relationship between reinforcing properties and sensory/motor toxicity of CNS depressants: Implications for the assessment of abuse liability.

1982 • 9 citations

The morning after: residual EEG effects of triazolam and flurazepam, alone and in combination with alcohol.

1976 • 9 citations

Triazolam: monitored release in the United Kingdom.

1981 • 6 citations

The morning after: residual EEG effects of triazolam and flurazepam, alone and in combination with alcohol.

1976 • 6 citations

Triazolam intoxication.

1982 • 6 citations

Anxiety caused by a short-life hypnotic

1982 • 5 citations

Commentary 2

1983 • 5 citations

Anxiety caused by a short-life hypnotic.

1982 • 4 citations

Hypnotics and anxiolytics.

1983 • 3 citations

Anxiety caused by a short-life hypnotic

1982 • 3 citations

Commentary 4

1983 • 1 citations

Haemofiltration for profound dialysis-induced hypotension: removal of sodium and water without blood-pressure change.

1982 • 1 citations