Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

1981 • 14,396 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

hnRNP PROTEINS AND THE BIOGENESIS OF mRNA

1993 • 1,486 citations

λ ZAP: a bacteriophage λ expression vector within vivoexcision properties

1988 • 1,394 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Autoimmune Response to Acetylcholine Receptor

1973 • 1,019 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions

1949 • 974 citations

Anti-Hu-Associated Paraneoplastic Encephalomyelitis/Sensory Neuronopathy A Clinical Study of 71 Patients

1992 • 812 citations

The engrailed locus of drosophila: Structural analysis of an embryonic transcript

1985 • 735 citations

Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section

1992 • 712 citations

Control of cell pattern in the developing nervous system: Polarizing activity of the floor plate and notochord

1991 • 698 citations

PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM

1960 • 692 citations

THE LAMBERT-EATON MYASTHENIC SYNDROME

1988 • 673 citations

Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin

1992 • 669 citations

Brain-derived neurotrophic factor rescues spinal motor neurons from axotomy-induced cell death

1992 • 668 citations

Cell death in the development of the lateral motor column of the chick embryo

1975 • 658 citations

Multiple D2 dopamine receptors produced by alternative RNA splicing

1989 • 642 citations

Early Stages of Motor Neuron Differentiation Revealed by Expression of Homeobox Gene Islet-1

1992 • 638 citations

Paraneoplastic cerebellar degeneration.

1992 • 578 citations

Recoverin: a Calcium Sensitive Activator of Retinal Rod Guanylate Cyclase

1991 • 569 citations

Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing

1984 • 563 citations

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

1992 • 559 citations

HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and sex-lethal

1991 • 553 citations

The pre-mRNA binding K protein contains a novel evolutionary conserved motif

1993 • 526 citations

Dorsal Root Ganglion Neurons Are Destroyed by Exposure in Utero to Maternal Antibody to Nerve Growth Factor

1980 • 500 citations

Characterization and localization of the even-skipped protein of Drosophila.

1987 • 496 citations

Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins

1988 • 461 citations

Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death

1992 • 458 citations

In vitro neurite extension by granule neurons is dependent upon astroglial-derived fibroblast growth factor

1988 • 408 citations

Pax in development

1992 • 402 citations

Anti‐Ri: An antibody associated with paraneoplastic opsoclonus and breast cancer

1991 • 402 citations

Segmental distribution of bithorax complex proteins during Drosophila development

1985 • 397 citations

Detection of the anti‐Hu antibody in the serum of patients with small cell lung cancer—A quantitative western blot analysis

1990 • 394 citations

F-spondin: A gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension

1992 • 382 citations

AUTOIMMUNE AETIOLOGY FOR MYASTHENIC (EATON-LAMBERT) SYNDROME

1981 • 366 citations

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1992 • 364 citations

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.

1993 • 356 citations

Fibroblast growth factors promote the survival of adult rat retinal ganglion cells after transection of the optic nerve

1987 • 355 citations

Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation

1989 • 355 citations

The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages

1988 • 351 citations

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development.

1990 • 342 citations

The elav Gene Product of Drosophila , Required in Neurons, Has Three RNP Consensus Motifs

1988 • 302 citations

Mesodermal Control of Neural Cell Identity: Floor Plate Induction by the Notochord

1990 • 300 citations

Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein.

1992 • 281 citations

More is better: Activators and repressors from the same gene

1992 • 280 citations

A photoreceptor calcium binding protein is recognized by autoantibodies obtained from patients with cancer-associated retinopathy.

1991 • 264 citations

Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol

1987 • 258 citations

Regression of small-cell lung carcinoma in patients with paraneoplastic neuronal antibodies

1993 • 254 citations

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes

1989 • 254 citations

Equine Infectious Anemia Virus gag and pol Genes: Relatedness to Visna and AIDS Virus

1986 • 252 citations

Comparison of two host cell range variants of feline immunodeficiency virus

1990 • 243 citations

Nucleotide sequence evidence for relationship of AIDS retrovirus to lentiviruses

1985 • 242 citations

Photoreceptor Deactivation and Retinal Degeneration Mediated by a Photoreceptor-Specific Protein Kinase C

1991 • 240 citations

Cancer-Associated Retinopathy (CAR Syndrome) with Antibodies Reacting with Retinal, Optic-Nerve, and Cancer Cells

1989 • 240 citations

The cancer-associated retinopathy antigen is a recoverin-like protein.

1992 • 234 citations

Drosophila Krüppel protein is a transcriptional represser

1990 • 228 citations

The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen.

1992 • 220 citations

Notochordal induction of cell wedging in the chick neural plate and its role in neural tube formation

1989 • 218 citations

Paraneoplastic cerebellar degeneration

1984 • 202 citations

Molecular cloning of multiple subtypes of a novel rat brain isoform of the α1 subunit of the voltage-dependent calcium channel

1991 • 194 citations

The effect of recoverin-like calcium-Binding proteins on the photoresponse of retinal rods

1993 • 194 citations

Meiosis-specific RNA splicing in yeast

1991 • 191 citations

Aplysia neurons express a gene encoding multiple FMRFamide neuropeptides

1985 • 189 citations

Paraneoplastic cerebellar degeneration: Clinical‐immunological correlations

1988 • 188 citations

Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit.

1992 • 164 citations

Opsoclonus in Adults

1986 • 164 citations

Cloning of a brain protein identified by autoantibodies from a patient with paraneoplastic cerebellar degeneration.

1987 • 162 citations

Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila.

1989 • 158 citations

Opsoclonus, Myoclonus, Ataxia, and Encephalopathy in Adults with Cancer

1988 • 150 citations

Cloning of a leucine-zipper protein recognized by the sera of patients with antibody-associated paraneoplastic cerebellar degeneration.

1991 • 145 citations

The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers.

1990 • 138 citations

MER1, a Yeast Gene Required for Chromosome Pairing and Genetic Recombination, Is Induced in Meiosis

1990 • 124 citations

Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene

1987 • 123 citations

Differential expression of two types of the neurofibromatosis type 1 (NF1) gene transcripts related to neuronal differentiation.

1991 • 119 citations

Sequence relationships of type D retroviruses which cause simian acquired immunodeficiency syndrome

1987 • 117 citations

The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development.

1991 • 111 citations

Segmental and developmental regulation of a presumptive T-cell oncogene in the central nervous system

1990 • 109 citations

Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain.

1988 • 108 citations

A developmentally regulated, nervous system-specific gene in Xenopus encodes a putative RNA-binding protein.

1990 • 101 citations

Isolation of a complementary DNA clone encoding an autoantigen recognized by an anti‐neuronal cell antibody from a patient with paraneoplastic cerebellar degeneration

1990 • 96 citations

An antineuronal autoantibody in paraneoplastic opsoclonus

1988 • 88 citations

EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5′ end of HOX4 locus on chromosome 2

1991 • 72 citations

Intrahippocampal injections of antiserum to nerve growth factor inhibit sympathohippocampal sprouting

1985 • 72 citations

MER1, a yeast gene required for chromosome pairing and genetic recombination, is induced in meiosis.

1990 • 70 citations

Common Properties of Proteins Encoded by the Antennapedia Complex Genes of Drosophila melanogaster

1985 • 70 citations

The developmental significance of the floor‐plate of the brain and spinal cord

1930 • 69 citations

Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein.

1993 • 68 citations

Cloning and characterization of a lambert‐eaton myasthenic syndrome antigen

1993 • 65 citations

Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors

1991 • 62 citations

The nucleolar protein, B-36, contains a glycine and dimethylarginine-rich sequence conserved in several other nuclear RNA-binding proteins

1988 • 53 citations

Sequence and embryonic expression of the murine Hox-3.5 gene

1992 • 53 citations

The neuronal nuclear antigen recognized by the human anti-Ri autoantibody is expressed in central but not peripheral nervous system neurons

1993 • 45 citations

Acetylcholine Receptors in Small Cell Carcinomas

1985 • 44 citations

Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors have been highly conserved during vertebrate evolution.

1990 • 41 citations

The influence of adjacent structures upon the shape of the neural tube and neural plate of chick embryos

1955 • 36 citations

Motorizing the spinal cord

1991 • 28 citations

ONCOCOGNITIVE AUTOIMMUNITY AND OTHER PARANEOPLASTIC SYNDROMES YET TO BE DESCRIBED

1974 • 25 citations

Interspecific comparisons of the structure and regulation of the Drosophila ecdysone-inducible gene E74.

1991 • 24 citations

isolation of human cDNA clones ofjun-related genes,jun-B andjun-D

1990 • 24 citations

Current Diagnosis In Neurology

1994 • 22 citations

Paraneoplastic syndromes: Unusual manifestations of malignant disease

1979 • 21 citations

Large Vineyard Discovered in Ancient Pompeii

1973 • 10 citations

Immunologic mechanisms in neurologic and psychiatric disease

1990 • 9 citations

Diseases of the myoneural junction.

1990 • 4 citations