Questions to be answered regarding umbilical cord blood hematopoietic stem and progenitor cells and their use in‐transplantation

Hematopoietic Reconstitution in a Patient with Fanconi's Anemia by Means of Umbilical-Cord Blood from an HLA-Identical Sibling

1989 • 2,107 citations

Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells.

1989 • 1,220 citations

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

1994 • 1,133 citations

Cytokine Stimulation of Multilineage Hematopoiesis from Immature Human Cells Engrafted in SCID Mice

1992 • 555 citations

Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults.

1992 • 506 citations

Ontogeny-related changes in proliferative potential of human hematopoietic cells.

1993 • 413 citations

Stored placental blood for unrelated bone marrow reconstitution

1993 • 400 citations

Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice

1994 • 283 citations

Enrichment, characterization, and responsiveness of single primitive CD34 human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential

1993 • 235 citations

Transplantation of umbilical cord blood after myeloablative therapy: analysis of engraftment [see comments]

1992 • 220 citations

Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation.

1991 • 219 citations

Growth of human umbilical-cord blood in longterm haemopoietic cultures

1992 • 217 citations

Studies of human cord blood dendritic cells: evidence for functional immaturity

1994 • 196 citations

Release from quiescence of CD34+ CD38- human umbilical cord blood cells reveals their potentiality to engraft adults.

1993 • 189 citations

Proliferative and Cytotoxic Responses of Human Cord Blood T Lymphocytes Following Allogeneic Stimulation

1994 • 187 citations

Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood

1994 • 178 citations

Direct comparison by limiting dilution analysis of long-term culture- initiating cells in human bone marrow, umbilical cord blood, and blood stem cells

1994 • 170 citations

Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep.

1994 • 155 citations

Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector.

1994 • 137 citations

Search for maternal cells in human umbilical cord blood by polymerase chain reaction amplification of two minisatellite sequences

1994 • 135 citations

Evaluation of the in vitro behavior of phenotypically defined populations of umbilical cord blood hematopoietic progenitor cells.

1994 • 129 citations

Alloantigen priming induces a state of unresponsiveness in human umbilical cord blood T cells.

1995 • 125 citations

Human cord blood cells as targets for gene transfer: potential use in genetic therapies of severe combined immunodeficiency disease.

1993 • 122 citations

What defines a pluripotent hematopoietic stem cell (PHSC): will the real PHSC please stand up! [editorial]

1994 • 121 citations

Candidacidal mechanisms in the human neonate. Impaired IFN-gamma activation of macrophages in newborn infants.

1994 • 120 citations

Unrelated placental blood for bone marrow reconstitution: organization of the placental blood program.

1994 • 118 citations

Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood.

1994 • 114 citations

Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: an effect enhanced by cord blood plasma

1993 • 112 citations

Persistence of human multilineage, self-renewing lymphohematopoietic stem cells in chimeric sheep

1993 • 112 citations

Cytokine-induced selective expansion and maturation of erythroid versus myeloid progenitors from purified cord blood precursor cells

1993 • 110 citations

Long-term generation of colony-forming cells in liquid culture of CD34+ cord blood cells in the presence of recombinant human stem cell factor

1992 • 108 citations

The use of umbilical cord blood in mismatched related and unrelated hemopoietic stem cell transplantation.

1994 • 107 citations

High efficiency retroviral mediated gene transduction into single isolated immature and replatable CD34(3+) hematopoietic stem/progenitor cells from human umbilical cord blood.

1993 • 106 citations

Comparative effects of suppressive cytokines on isolated single CD34(3+) stem/progenitor cells from human bone marrow and umbilical cord blood plated with and without serum.

1993 • 101 citations

Correction of X-Linked Lymphoproliferative Disease by Transplantation of Cord-Blood Stem Cells

1993 • 88 citations

A functionally active retrovirus vector for gene therapy in Fanconi anemia group C

1994 • 85 citations

Engraftment of human hematopoietic precursor cells with secondary transfer potential in SCID-hu mice

1994 • 80 citations

Ex vivo expansion of cord blood-derived stem cells and progenitors.

1994 • 79 citations

Transforming growth factor-beta 1, macrophage inflammatory protein-1 alpha, and interleukin-8 gene expression is lower in stimulated human neonatal compared with adult mononuclear cells

1994 • 77 citations

Adeno-associated virus 2-mediated gene transfer in murine hematopoietic progenitor cells.

1993 • 69 citations

Reconstitution of SCID mice with human lymphoid and myeloid cells after transplantation with human fetal bone marrow without the requirement for exogenous human cytokines.

1994 • 68 citations

Haemopoietic stem/progenitor cell transplant in Fanconi anaemia using HLA‐matched sibling umbilical cord blood cells

1993 • 66 citations

HLA-MISMATCHD CORD-BLOOD TRANSPLANATION IN A PATIENT WITH ADVANCED LEUKEMIA

1992 • 66 citations

Allogeneic responses of human umbilical cord blood.

1994 • 62 citations

Proposed policies and procedures for the establishment of a cord blood bank.

1994 • 60 citations

Successful hematopoietic reconstitution with transplantation of erythrocyte-depleted allogeneic human umbilical cord blood cells in a child with leukemia.

1994 • 57 citations

Harvesting, characterization, and culture of CD34+ cells from human bone marrow, peripheral blood, and cord blood.

1994 • 57 citations

The Lack of NK Cytotoxicity Associated with Fresh HUCB May Be Due to the Presence of Soluble HLA in the Serum

1994 • 54 citations

Can cord blood be used?

1989 • 51 citations

Frontiers in bone marrow transplantation.

1991 • 50 citations

Hematopoietic Stem Cells: Biology and Therapeutic Applications

1995 • 47 citations

Expansion in bioreactors of human progenitor populations from cord blood and mobilized peripheral blood.

1994 • 45 citations

Retention and multilineage expression of human hematopoietic stem cells in human‐sheep chimeras

1995 • 40 citations

Decreased macrophage colony-stimulating factor mRNA expression from activated cord versus adult mononuclear cells: altered posttranscriptional stability

1994 • 38 citations

Cytokine-dependent ex vivo expansion of early subsets of CD34+ cord blood myeloid progenitors is enhanced by cord blood plasma, but expansion of the more mature subsets of progenitors is favored.

1994 • 36 citations

Umbilical cord blood infusion in a patient for correction of Wiskott-Aldrich syndrome.

1994 • 33 citations

Human umbilical cord blood hematopoietic progenitor cells: are they the same as their adult bone marrow counterparts?

1994 • 32 citations

UMBILICAL CORD BLOOD TRANSPLANTATION IN A PATIENT WITH PHILADELPHIA CHROMOSOME-POSITIVE CHRONIC MYELOID LEUKEMIA

1993 • 30 citations

Umbilical cord blood cell transduction by retroviral vectors: preclinical studies to optimize gene transfer.

1994 • 29 citations

Extensive proliferative capacity of single isolated CD34 human cord blood cells in suspension culture.

1994 • 22 citations

Cord blood plasma-mediated ex vivo expansion of hematopoietic progenitor cells.

1994 • 20 citations

Comparative analysis of retroviral-mediated gene transduction into CD34+ cord blood hematopoietic progenitors in the presence and absence of growth factors.

1994 • 20 citations

Scientific Basis of Transfusion Medicine: Implications for Clinical Practice

1995 • 20 citations

Umbilical cord blood stem cells as targets for genetic modification: new therapeutic approaches to somatic gene therapy.

1994 • 18 citations

Rapid isolation and serum-free expansion of human CD34+ cells.

1994 • 17 citations

Stem cell factor enhances the survival of irradiated human bone marrow maintained in SCID mice

1994 • 15 citations

Isolation and ex vivo expansion of CD34+ cells from cord blood using dextran sedimentation and avidin column selection.

1994 • 15 citations

Cord blood transplantation in thalassemia.

1994 • 15 citations

Expansion of human neonatal progenitor cells in vitro under serum-deprived conditions.

1994 • 12 citations

Erythrocyte-depleted allogeneic human umbilical cord blood transplantation.

1994 • 9 citations

Use of granulocyte-macrophage colony-stimulating factor in two children treated with cord blood transplantation.

1994 • 8 citations

Commentary: cord blood banking for bone marrow reconstitution: a need for standardization and international cooperation.

1994 • 5 citations