lynx1, an Endogenous Toxin-like Modulator of Nicotinic Acetylcholine Receptors in the Mammalian CNS

Basic local alignment search tool

1990 • 87,358 citations

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

1983 • 14,615 citations

Comparative Protein Modelling by Satisfaction of Spatial Restraints

1993 • 12,640 citations

Recognition of errors in three-dimensional structures of proteins

1993 • 2,084 citations

CENTRAL CHOLINERGIC SYSTEMS AND COGNITION

1997 • 1,328 citations

Hippocampal synaptic transmission enhanced by low concentrations of nicotine

1996 • 955 citations

Neural correlates of attention and arousal: insights from electrophysiology, functional neuroimaging and psychopharmacology

1998 • 864 citations

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1995 • 659 citations

HOW GLYCOSYL-PHOSPHATIDYLINOSITOL-ANCHORED MEMBRANE PROTEINS ARE MADE

1995 • 478 citations

Arousal systems and attentional processes

1997 • 427 citations

THE USE OF ANIMAL MODELS TO STUDY THE EFFECTS OF AGING ON COGNITION

1997 • 414 citations

Diffuse transmission by acetylcholine in the CNS

1997 • 407 citations

Large-scale protein structure modeling of the Saccharomyces cerevisiae genome

1998 • 358 citations

Evolutionary relationships and implications for the regulation of phospholipase A2 from snake venom to human secreted forms

1990 • 328 citations

Brain nicotinic receptors: structure and regulation, role in learning and reinforcement

1998 • 314 citations

Evaluation of comparative protein structure modeling by MODELLER-3

1997 • 254 citations

Immunocytochemical localization of the α7 subunit of the nicotinic acetylcholine receptor in the rat central nervous system

1994 • 247 citations

Molecular Evolution of Snake Toxins: Is the Functional Diversify of Snake Toxins Associated with a Mechanism of Accelerated Evolution?

1997 • 200 citations

The α-Bungarotoxin-binding Nicotinic Acetylcholine Receptor from Rat Brain Contains Only the α7 Subunit

1997 • 200 citations

Synapses on the purkinje cell spines in the mouse an electronmicroscopic study

1967 • 198 citations

Activity of the δ-Opioid Receptor Is Partially Reduced, Whereas Activity of the κ-Receptor Is Maintained in Mice Lacking the μ-Receptor

1998 • 193 citations

Abnormalities of neural circuitry in Alzheimer's disease

1998 • 179 citations

Changing patterns of gene expression define four stages of cerebellar granule neuron differentiation

1993 • 177 citations

Structure of a soluble, glycosylated form of the human complement regulatory protein CD59

1994 • 175 citations

Ultrastructural characterization of the acetylcholine innervation in adult rat neostriatum

1996 • 173 citations

Tissue expression, structure and function of the murine Ly‐6 family of molecules

1995 • 159 citations

Accelerated Evolution and Molecular Surface of Venom Phospholipase A2 Enzymes

1999 • 156 citations

The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion.

1995 • 135 citations

Recent studies on dendrotoxins and potassium ion channels

1997 • 131 citations

Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins.

1993 • 114 citations

Snake Venom Cardiotoxins-Structure, Dynamics, Function and Folding

1997 • 101 citations

NMR solution structure of an .alpha.-bungarotoxin/nicotinic receptor peptide complex

1993 • 94 citations

A toxin from the green mamba Dendroaspis angusticeps: Amino acid sequence and selectivity for muscarinic m4 receptors

1994 • 92 citations

Cognitive enhancers in theory and practice: studies of the cholinergic hypothesis of cognitive deficits in Alzheimer's disease

1997 • 90 citations

Ly-6C regulates endothelial adhesion and homing of CD8⁺T cells by activating integrin-dependent adhesion pathways

1997 • 81 citations

Genomic sequences encoding the acidic and basic subunits of Mojave toxin: unusually high sequence identity of non-coding regions

1994 • 72 citations

Muscarinic receptor subtype selective toxins

1997 • 72 citations

Sarafotoxins and endothelins: evolution, structure and function

1993 • 69 citations

A Novel Neurotoxin, Cobrotoxin b, from Naja naja atra (Taiwan Cobra) Venom: Purification, Characterization, and Gene Organization

1997 • 65 citations

Structure of the snake short‐chain neurotoxin, erabutoxin c, precursor gene

1990 • 48 citations

Genomic Structures of Cardiotoxin 4 and Cobrotoxin fromNaja Naja Atra(Taiwan Cobra)

1997 • 48 citations

.alpha.-Cobratoxin: proton NMR assignment and solution structure

1992 • 45 citations

Identification of a Novel Type of Alternatively Spliced Exon from the Acetylcholinesterase Gene of Bungarus fasciatus

1998 • 45 citations

Studies on the mechanism of interactions between anesthetic steroids and gamma-aminobutyric acidA receptors.

1990 • 43 citations

Immunohistochemical localization of substance P and enkephalin in the nucleus tractus solitarii of the rhesus monkey, Macaca mulatta

1987 • 31 citations

The Evolution of Toxins Found in Snake Venoms

1979 • 30 citations

The long and the short of snake toxins

1989 • 22 citations

Amino acid sequences of nerve growth factors derived from cobra venoms

1991 • 19 citations

A gain of novel tissue specificity in the human Ly-6 gene E48.

1997 • 16 citations

Sequence and structure of the mouse ThB gene

1995 • 9 citations

Role of glutamate receptor subtypes in the differential release of somatostatin, neuropeptide Y, and substance P in primary serum-free cultures of striatal neurons

1997 • 9 citations

Two Novel α-Neurotoxins Isolated from Taiwan Cobra: Sequence Characterization and Phylogenetic Comparison of Homologous Neurotoxins

1998 • 6 citations