Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript

An analysis of vertebrate mRNA sequences: intimations of translational control.

1991 • 1,655 citations

Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism

1998 • 1,504 citations

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

1995 • 1,416 citations

Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice

1996 • 1,219 citations

Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain

1996 • 943 citations

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

Multiple promoters direct tissue-specific expression of the rat BDNF gene

1993 • 851 citations

Identification of a Signaling Pathway Involved in Calcium Regulation of BDNF Expression

1998 • 687 citations

Do the poly(A) tail and 3′ untranslated region control mRNA translation?

1990 • 618 citations

Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca²⁺ Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons

1995 • 616 citations

Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors.

1995 • 612 citations

Light regulates expression of brain-derived neurotrophic factor mRNA in rat visual cortex.

1992 • 515 citations

Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment

1992 • 386 citations

Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus

1998 • 360 citations

Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone

1998 • 356 citations

Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice.

1996 • 350 citations

BDNF Protein Measured by a Novel Enzyme Immunoassay in Normal Brain and after Seizure: Partial Disagreement with mRNA Levels

1995 • 328 citations

Brain-Derived Neurotrophic Factor Protects against Ischemic Cell Damage in Rat Hippocampus

1994 • 326 citations

The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus

1993 • 313 citations

Activity‐dependent and hormonal regulation of neurotrophin mRNA levels in brain–implications for neuronal plasticity

1994 • 297 citations

Brain-derived neurotrophic factor administration protects basal forebrain cholinergic but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain

1992 • 281 citations

Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection

1993 • 254 citations

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

1998 • 228 citations

Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats

1997 • 226 citations

Release of acetylcholine from the hippocampus of freely moving rats during sensory stimulation and running

1979 • 213 citations

Acute Intrahippocampal Infusion of BDNF Induces Lasting Potentiation of Synaptic Transmission in the Rat Dentate Gyrus

1998 • 207 citations

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

1998 • 205 citations

Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat hippocampus

1993 • 204 citations

Upregulation of BDNF mRNA Expression in the Barrel Cortex of Adult Mice after Sensory Stimulation

1996 • 186 citations

Differential Effects of Protein Synthesis Inhibition on the Activity-Dependent Expression of BDNF Transcripts: Evidence for Immediate-Early Gene Responses from Specific Promoters

1996 • 166 citations

Acetylcholine release in the rat hippocampus as studied by microdialysis is dependent on axonal impulse flow and increases during behavioural activation

1990 • 149 citations

NGF and BDNF are differentially modulated by visual experience in the developing geniculocortical pathway

1995 • 149 citations

Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor andβ-nerve growth factor mRNA in rat hippocampus

1992 • 122 citations

Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat

1995 • 116 citations

Brain Insults in Rats Induce Increased Expression of the BDNF Gene through Differential Use of Multiple Promoters

1994 • 113 citations

BDNF and trkB mRNAs oscillate in rat brain during the light–dark cycle

1998 • 110 citations

C‐fos mRNA is Spontaneously Induced in the Rat Brain During the Activity Period of the Circadian Cycle

1993 • 109 citations

Translational discrimination of mRNAs coding for human insulin-like growth factor II.

1990 • 108 citations

Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizures

1998 • 107 citations

Circadian rhythm of brain-derived neurotrophic factor in the rat suprachiasmatic nucleus

1998 • 103 citations

Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat

1996 • 101 citations

Acetylcholine release in the rat hippocampus as measured by the microdialysis method correlates with motor activity and exhibits a diurnal variation

1991 • 96 citations

Circadian rhythm in c-fos-like immunoreactivity in the rat brain

1990 • 93 citations

Tissue specific expression of the retinoic acid receptor-beta 2: regulation by short open reading frames in the 5'-noncoding region.

1994 • 85 citations

Cholinergic regulation of hippocampal brain-derived neurotrophic factor mRNA expression: Evidence from lesion and chronic cholinergic drug treatment studies

1993 • 83 citations

Distinctive four promoters collectively direct expression of brain-derived neurotrophic factor gene

1994 • 82 citations

Differential association of insulin-like growth factor I mRNA variants with polysomes in vivo.

1991 • 72 citations

Alternate 5′ exons in the rat brain-derived neurotrophic factor gene: differential patterns of expression across brain regions

1994 • 67 citations

Analysis of transcriptional initiation and translatability of brain-derived neurotrophic factor mRNAs in the rat brain

1994 • 43 citations

Organization, sequence and functional analysis of a mouse BDNF promoter

1997 • 40 citations

Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus

1998 • 31 citations

Spontaneous acetylcholine release in the hippocampus exhibits a diurnal variation in both young and old rats

1994 • 30 citations

Activation of basal forebrain cholinergic neurons differentially regulates brain-derived neurotrophic factor mRNA expression in different projection areas

1992 • 27 citations

Differential expression pattern of jun B and c-jun in the rat brain during the 24-h cycle

1994 • 21 citations

Combination of gene targeting and gene transfer by adenoviral vectors in the analysis of neurotrophin-mediated neuronal plasticity.

1996 • 6 citations

Ibotenic acid in the medial septum increased brain-derived neurotrophic factor mRNA levels in the dorsal rat hippocampal formation

1996 • 5 citations

Ibotenic acid in the medial septum increased brain-derived neurotrophic factor mRNA levels in the dorsal rat hippocampal formation

1996 • 1 citations