Human and rat malignant-tumor-associated mRNAs encode stromelysin-like metalloproteinases

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

1986 • 1,408 citations

CELL SURFACE INTERACTIONS WITH EXTRACELLULAR MATERIALS

1983 • 1,147 citations

Chapter 1: Interferons (IFNs)

1986 • 793 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase.

1985 • 625 citations

Complete sequence of the staphylococcal gene encoding protein A. A gene evolved through multiple duplications.

1984 • 571 citations

A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization.

1986 • 515 citations

Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

1985 • 506 citations

Proteolytic degradation of extracellular matrix in tumor invasion

1987 • 484 citations

Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

1987 • 474 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

[30] Gel protein stains: Silver stain

1984 • 365 citations

The collagenase gene family in humans consists of at least four members

1988 • 364 citations

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

1979 • 350 citations

Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

1986 • 339 citations

Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.

1987 • 323 citations

The role of proteinase in cellular invasiveness

1983 • 297 citations

Helper-independent transformation by unintegrated Harvey sarcoma virus DNA

1978 • 277 citations

New versatile cloning and sequencing vectors based on bacteriophage M13

1983 • 263 citations

The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.

1986 • 260 citations

Purification and characterization of a murine basement membrane collagen-degrading enzyme secreted by metastatic tumor cells.

1983 • 245 citations

Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid.

1983 • 231 citations

Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components

1983 • 222 citations

Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase.

1985 • 220 citations

Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamethasone.

1987 • 217 citations

Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin

1983 • 208 citations

Partial purification of collagenase and gelatinase from human polymorphonuclear leucocytes. Analysis of their actions on soluble and insoluble collagens

1982 • 203 citations

Induction of collagenase secretion in human fibroblast cultures by growth promoting factors.

1985 • 186 citations

The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products.

1987 • 173 citations

An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases

1981 • 171 citations

Structure-function relationships in the collagenase family member transin.

1988 • 169 citations

Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans

1978 • 149 citations

Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-trans-retinoic acid or dexamethasone

1986 • 140 citations

Purification of an endogenous activator of procollagenase from rabbit synovial fibroblast culture medium.

1983 • 134 citations

Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene

1987 • 127 citations

Current views of collagen degeradation. Progress towards understanding the resorption of connective tissues

1985 • 121 citations

A gene for rabbit synovial cell collagenase: member of a family of metalloproteinases that degrades the connective tissue matrix

1987 • 115 citations

Oligonucleotide-directed mutagenesis by microscale ‘shot-gun’ gene synthesis

1985 • 105 citations

An improved assay for proteases and polysaccharidases employing a cartilage proteoglycan substrate entrapped in polyacrylamide particles

1980 • 83 citations

Purification and properties of a specific collagenase from rabbit synovial fibroblasts

1975 • 37 citations

Proactivator-dependent activation of procollagenase induced by treatment with EGTA

1986 • 24 citations