The role of growth factors in self-renewal and differentiation of haemopoietic stem cells

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells

1961 • 3,579 citations

The relationship between the spleen colony-forming cell and the haemopoietic stem cell.

1978 • 2,290 citations

The Human Hematopoietic Colony-Stimulating Factors

1987 • 1,728 citations

Interleukin-1

1984 • 1,625 citations

The Granulocyte-Macrophage Colony-Stimulating Factors

1985 • 1,007 citations

A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS

1964 • 889 citations

Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

1988 • 845 citations

Growth of factor-dependent hemopoietic precursor cell lines.

1980 • 793 citations

Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment

1987 • 636 citations

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1978 • 593 citations

Purification and biochemical characterization of human pluripotent hematopoietic colony-stimulating factor.

1985 • 522 citations

Transient nature of early haematopoietic spleen colonies

1982 • 377 citations

Isolation of murine pluripotent hemopoietic stem cells.

1984 • 333 citations

Hemopoietic stem cell differentiation

1980 • 333 citations

Stromal cell associated haemopoiesis

1982 • 325 citations

Interleukin 1 regulates hematopoietic activity, a role previously ascribed to hemopoietin 1.

1987 • 309 citations

The ultrastructure of the hemopoietic environment of the marrow: a review.

1981 • 308 citations

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

1986 • 288 citations

Hemopoietic spleen colony studies

1967 • 286 citations

Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1

1986 • 283 citations

Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1)

1981 • 274 citations

Control of hemopoiesis by a bone marrow stromal cell clone: lipopolysaccharide- and interleukin-1-inducible production of colony- stimulating factors

1987 • 263 citations

The persisting (P) cell: histamine content, regulation by a T cell-derived factor, origin from a bone marrow precursor, and relationship to mast cells.

1981 • 234 citations

Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors.

1984 • 233 citations

Transforming growth factor beta 1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3-dependent myeloid leukemia cell lines.

1988 • 222 citations

Proliferative effects of purified granulocyte colony‐stimulating factor (G‐CSF) on normal mouse hemopoietic cells

1983 • 221 citations

A stochastic model of self‐renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture

1982 • 199 citations

Direct stimulation by purified GM-CSF of the proliferation of multipotential and erythroid precursor cells

1980 • 188 citations

Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells.

1987 • 168 citations

Self-renewal of hemopoietic stem cells during mixed colony formation in vitro.

1981 • 153 citations

The molecular control of blood cells

1988 • 146 citations

Cells with marrow and spleen repopulating ability and forming spleen colonies on day 16, 12, and 8 are sequentially ordered on the basis of increasing rhodamine 123 retention

1988 • 101 citations

Interleukin 3 promotes the in vitro proliferation of murine pluripotent hematopoietic stem cells.

1985 • 98 citations

Investigations of a stochastic model of haemopoiesis.

1973 • 84 citations

Isolation of haemopoietic spleen colony forming cells.

1986 • 76 citations

Long term bone marrow cultures: an ultrastructural review.

1983 • 52 citations

The response of haemopoietic cells to growth factors: developmental implications of synergistic interactions

1988 • 47 citations

Comparison of haemopoiesis in young and old mice

1986 • 40 citations

The Effects of TGFβ on Haemopoietic Cells

1989 • 33 citations

Stromal cell regulation of lymphoid and myeloid differentiation.

1987 • 32 citations

The development of cell lineages: A sequential model

1988 • 27 citations

Development of spleen CFU-S colonies from day 8 to day 11: relationship to self-renewal capacity.

1986 • 24 citations

Molecular Structure and Biological Activities of P Cell-Stimulating Factor (Interleukin 3)

1988 • 11 citations

Erythropoietin

1989 • 6 citations