Binding of nucleic acids to E.coli RNase HI observed by NMR and CD spectroscopy

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

Ion effects on ligand-nucleic acid interactions

1976 • 1,016 citations

Structure of a B-DNA dodecamer

1981 • 891 citations

Origins and Evolutionary Relationships of Retroviruses

1989 • 581 citations

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

1991 • 566 citations

Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods

1983 • 548 citations

Structure of the DNA-Eco RI Endonuclease Recognition Complex at 3 Å Resolution

1986 • 492 citations

Structure of Ribonuclease H Phased at 2 Å Resolution by MAD Analysis of the Selenomethionyl Protein

1990 • 475 citations

Site specific enzymatic cleavage of RNA

1979 • 400 citations

Three-dimensional structure of ribonuclease H from E. coli

1990 • 348 citations

Structure refined to 2Å of a nicked DNA octanucleotide complex with DNase I

1988 • 293 citations

Sequence‐dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H

1987 • 261 citations

Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution

1992 • 228 citations

Molecular structure of r(GCG)d(TATACGC): a DNA–RNA hybrid helix joined to double helical DNA

1982 • 208 citations

How does RNase H recognize a DNA.RNA hybrid?

1991 • 188 citations

Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations

1992 • 186 citations

Identification of the amino acid residues involved in an active site of Escherichia coli ribonuclease H by site-directed mutagenesis.

1990 • 176 citations

Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution

1982 • 173 citations

The DNA strand in DNA.cntdot.RNA hybrid duplexes is neither B-form nor A-form in solution

1993 • 134 citations

Crystal Structure of Ribonuclease H from Thermus thermophilus HB8 Refined at 2·8 Å Resolution

1993 • 119 citations

A RNA.DNA hybrid that can adopt two conformations: an x-ray diffraction study of poly(rA).poly(dT) in concentrated solution or in fibers.

1981 • 105 citations

DNA-RNA hybrid secondary structures

1986 • 105 citations

Solid-phase synthesis and high-resolution NMR studies of two synthetic double-helical RNA dodecamers: r(CGCGAAUUCGCG) and r(CGCGUAUACGCG)

1989 • 85 citations

Role of histidine 124 in the catalytic function of ribonuclease HI from Escherichia coli.

1993 • 82 citations

Ribonucleases H of retroviral and cellular origin

1990 • 72 citations

Ribonuclease H: from discovery to 3D structure.

1990 • 70 citations

High-resolution NMR study of a synthetic DNA-RNA hybrid dodecamer containing the consensus Pribnow promoter sequence: d(CGTTATAATGCG).cntdot.r(CGCAUUAUAACG)

1989 • 68 citations

5'-Levulinyl and 2'-tetrahydrofuranyl protection for the synthesis of oligoribonucleotides by the phosphoramidite approach

1988 • 56 citations

pH-Dependent thermostabilization of Escherichia coli ribonuclease HI by histidine to alanine substitutions

1993 • 52 citations

A solution structure for poly(rA).cntdot.poly(dT) with different furanose pucker and backbone geometry in rA and dT strands and intrastrand hydrogen bonding of adenine 8CH

1988 • 51 citations

Assignments of backbone proton, carbon-13, and nitrogen-15 resonances and secondary structure of ribonuclease H from Escherichia coli by heteronuclear three-dimensional NMR spectroscopy

1991 • 48 citations

Binding of metal ions toE. coli RNase HI observed by1H−15N heteronuclear 2D NMR

1991 • 39 citations

Secondary structure of the hybrid poly(rA) · poly(dT) in solution

1985 • 32 citations

Direct evidence for a bimorphic structure of a DNA-RNA hybrid, poly(rA).poly(dT), at high relative humidity.

1984 • 25 citations