Modulation of interleukin 1 beta gene expression by the immediate early genes of human cytomegalovirus.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Interleukin-1

1984 • 1,625 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

Biology of interleukin 1

1988 • 1,547 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.

1987 • 413 citations

Cytomegalovirus infects human lymphocytes and monocytes: virus expression is restricted to immediate-early gene products.

1984 • 407 citations

Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

1986 • 384 citations

Translational Blockade Imposed by Cytokine-Derived UA-Rich Sequences

1989 • 347 citations

Characterization of enhancer elements in the long terminal repeat of Moloney murine sarcoma virus

1984 • 341 citations

Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus.

1987 • 317 citations

Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element

1989 • 311 citations

Temporal Patterns of Human Cytomegalovirus Transcription: Mapping the Viral RNAs Synthesized at Immediate Early, Early, and Late Times After Infection

1982 • 311 citations

Activation of the major immediate early gene of human cytomegalovirus by cis-acting elements in the promoter-regulatory sequence and by virus-specific trans-acting components

1985 • 245 citations

trans-activation and autoregulation of gene expression by the immediate-early region 2 gene products of human cytomegalovirus

1988 • 237 citations

Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter

1987 • 223 citations

Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways.

1988 • 206 citations

Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene

1986 • 205 citations

Transcription in human fibroblasts permissively infected by human cytomegalovirus strain AD169

1983 • 199 citations

Stimulation of Cellular DNA Synthesis by Human Cytomegalovirus

1974 • 197 citations

Synthesis of Proteins and Glycoproteins in Cells Infected with Human Cytomegalovirus

1977 • 184 citations

Cytomegalovirus Infection of Human Blood Cells

1984 • 183 citations

HIV and HCMV coinfect brain cells in patients with AIDS

1988 • 180 citations

The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.

1987 • 177 citations

Transcriptional regulation of the human prointerleukin 1 beta gene.

1987 • 172 citations

The promoter-regulatory region of the major immediate-early gene of human cytomegalovirus responds to T-lymphocyte stimulation and contains functional cyclic AMP-response elements

1989 • 164 citations

Phorbol ester-induced differentiation permits productive human cytomegalovirus infection in a monocytic cell line.

1988 • 146 citations

Molecular biology and immunology of cytomegalovirus

1987 • 128 citations

Posttranscriptional gene regulation and specific binding of the nonhistone protein HMG-I by the 3' untranslated region of bovine interleukin 2 cDNA.

1987 • 128 citations

Regulated expression of the human cytomegalovirus pp65 gene: octamer sequence in the promoter is required for activation by viral gene products

1989 • 126 citations

Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene

1988 • 121 citations

Human cytomegalovirus stimulates host cell RNA synthesis

1975 • 118 citations

A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection

1989 • 112 citations

Autoregulation of the human cytomegalovirus major immediate-early gene

1985 • 107 citations

Monocyte-derived inhibitor of interleukin 1 induced by human cytomegalovirus

1985 • 92 citations

Idiopathic production of interleukin-1 in acquired immune deficiency syndrome

1987 • 91 citations

Cytomegalovirus infection of peripheral blood mononuclear cells: effects on interleukin-1 and -2 production and responsiveness

1988 • 86 citations

Post-transcriptional control of human cytomegalovirus gene expression

1983 • 69 citations

Replication of human cytomegalovirus DNA: lack of dependence on cell DNA synthesis

1976 • 58 citations

Cytomegalovirus: Biology and Infection

1983 • 24 citations