Thioredoxin Domain Non-equivalence and Anti-chaperone Activity of Protein Disulfide Isomerase Mutants in Vivo

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Protein folding in the cell

1992 • 4,138 citations

Baculovirus expression vectors: a laboratory manual.

1992 • 1,799 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

1987 • 1,703 citations

Trends in the Development of Baculovirus Expression Vectors

1988 • 1,022 citations

Baculovirus expression vectors — A laboratory manual

1993 • 886 citations

Protein disulphide isomerase: building bridges in protein folding

1994 • 718 citations

Role of ATP and disulphide bonds during protein folding in the endoplasmic reticulum

1992 • 286 citations

Chaperone-like activity of protein disulfide isomerase in the refolding of a protein with no disulfide bonds.

1994 • 268 citations

Protein disulfide isomerase exhibits chaperone and anti-chaperone activity in the oxidative refolding of lysozyme.

1994 • 267 citations

The Essential Function of Protein-disulfide Isomerase Is to Unscramble Non-native Disulfide Bonds

1995 • 205 citations

Formation of aggregates from a thermolabile in vivo folding intermediate in P22 tailspike maturation. A model for inclusion body formation.

1988 • 199 citations

Protein Disulfide Isomerase Overexpression Increases Secretion of Foreign Proteins in Saccharomyces cerevisiae

1994 • 194 citations

Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein

1991 • 192 citations

Misfolding and aggregation of newly synthesized proteins in the endoplasmic reticulum.

1992 • 177 citations

High-level production of a functional immunoglobulin heterodimer in a baculovirus expression system.

1990 • 160 citations

Site-directed mutagenesis of human protein disulphide isomerase: effect on the assembly, activity and endoplasmic reticulum retention of human prolyl 4-hydroxylase in Spodoptera frugiperda insect cells.

1992 • 152 citations

Catalysis of Oxidative Protein Folding by Mutants of Protein Disulfide Isomerase with a Single Active-Site Cysteine

1996 • 151 citations

Expression and site-directed mutagenesis of human protein disulfide isomerase in Escherichia coli. This multifunctional polypeptide has two independently acting catalytic sites for the isomerase activity.

1992 • 144 citations

Functional properties of the individual thioredoxin-like domains of protein disulfide isomerase

1995 • 142 citations

Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system.

1992 • 135 citations

Peptide binding to protein disulfide isomerase occurs at a site distinct from the active sites.

1993 • 129 citations

Characterization of the active site cysteine residues of the thioredoxin-like domains of protein disulfide isomerase

1995 • 128 citations

Independence of the Chaperone Activity of Protein Disulfide Isomerase from Its Thioredoxin-like Active Site

1995 • 124 citations

Posttranslational folding of vesicular stomatitis virus G protein in the ER: involvement of noncovalent and covalent complexes.

1993 • 113 citations

In vivo cross-linking of protein disulfide isomerase to immunoglobulins

1987 • 113 citations

Baculovirus Expression Systems and Biopesticides

1996 • 111 citations

The role of the thiol/disulfide centers and peptide binding site in the chaperone and anti-chaperone activities of protein disulfide isomerase.

1994 • 104 citations

Mutations in the thioredoxin sites of protein disulfide isomerase reveal functional nonequivalence of the N- and C-terminal domains.

1994 • 93 citations

Influence of protein disulfide isomerase (PDI) on antibody folding in vitro.

1994 • 91 citations

Role of disulfide interchange enzyme in immunoglobulin synthesis

1981 • 90 citations

Identifying and Characterizing a Structural Domain of Protein Disulfide Isomerase

1996 • 88 citations

Effect of protein and peptide inhibitors on the activity of protein disulfide-isomerase

1991 • 87 citations

Coexpression of Molecular Chaperone BiP Improves Immunoglobulin Solubility and IgG Secretion from Trichoplusia ni Insect Cells

1997 • 86 citations

Eukaryotic Protein Disulfide Isomerase Complements Escherichia coli dsbA Mutants and Increases the Yield of a Heterologous Secreted Protein with Disulfide Bonds

1996 • 86 citations

Influence of different signal peptides and prosequences on expression and secretion of human tissue plasminogen activator in the baculovirus system

1993 • 84 citations

Antibody Production in Baculovirus-Infected Insect Cells

1990 • 81 citations

Peptide binding by protein disulfide isomerase, a resident protein of the endoplasmic reticulum lumen.

1991 • 78 citations

Baculovirus expression systems and biopesticides.

1994 • 74 citations

Effects of Co-Expressing Chaperone BiP on Functional Antibody Production in the Baculovirus System

1994 • 61 citations

Co‐expression of human protein disulphide isomerase (PDI) can increase the yield of an antibody Fab′ fragment expressed inEscherichia coli

1996 • 53 citations

Rescue of Immunoglobulins from Insolubility Is Facilitated by PDI in the Baculovirus Expression System

1996 • 50 citations

Baculovirus expression of two protein disulphide isomerase isoforms from Caenorhabditis elegans and characterization of prolyl 4-hydroxylases containing one of these polypeptides as their β subunit

1996 • 37 citations

Oxidation of Kinetically Trapped Thiols by Protein Disulfide Isomerase

1995 • 37 citations

Disulfide bond formation and eukaryotic secretory productivity

1995 • 36 citations

Using Molecular Genetics to Improve the Production of Recombinant Proteins by the Yeast Saccharomyces cerevisiae

1994 • 36 citations

Comparison of oligosaccharide processing among various insect cell lines expressing a secreted glycoprotein

1993 • 35 citations

Dithiothreitol treatment induces heterotypic aggregation of newly synthesized secretory proteins in HepG2 cells.

1994 • 22 citations

Engineering the Assembly Pathway of the Baculovirus‐Insect Cell Expression System^a

1994 • 15 citations

Baculovirus Expression of Gene 6 of the IDIR Strain of Group B Rotavirus (GBR): Coding Assignment of the Major Inner Capsid Protein

1993 • 9 citations