Colorectal Cancer Vaccines: Antiidiotypic Antibody, Recombinant Protein, and Viral Vector

Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma

1994 • 647 citations

Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies.

1979 • 638 citations

Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial.

1998 • 530 citations

Immunizing Patients With Metastatic Melanoma Using Recombinant Adenoviruses Encoding MART-1 or gp100 Melanoma Antigens

1998 • 306 citations

Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma.

1983 • 286 citations

The epithelial cell surface antigen 17–1A, a target for antibody‐mediated tumor therapy: Its biochemical nature, tissue distribution and recognition by different monoclonal antibodies

1986 • 243 citations

Anti-idiotype immunization of cancer patients: modulation of the immune response.

1987 • 190 citations

Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2.

1990 • 180 citations

Anti-Idiotypic Antibodies Bear the Internal Image of a Human Tumor Antigen

1986 • 126 citations

Clinical and immune responses in advanced colorectal cancer patients treated with anti-idiotype monoclonal antibody vaccine that mimics the carcinoembryonic antigen.

1997 • 119 citations

Melanoma Antigens: Immunological and Biological Characterization and Clinical Significance

1988 • 116 citations

Efficient selection of human tumor growth-inhibiting monoclonal antibodies

1984 • 110 citations

Carbohydrate vaccines that induce antibodies against cancer. 1. Rationale

1997 • 100 citations

Vaccination against tumor cells expressing breast cancer epithelial tumor antigen.

1990 • 95 citations

Carbohydrate vaccines that induce antibodies against cancer. 2. Previous experience and future plans

1997 • 92 citations

THE IMMUNOTHERAPY OF SOLID CANCERS BASED ON CLONING THE GENES ENCODING TUMOR-REJECTION ANTIGENS

1996 • 91 citations

Inhibition of human tumor growth by IgG2A monoclonal antibodies correlates with antibody density on tumor cells.

1985 • 77 citations

Colorectal Carcinoma Invasion Inhibition by CO17-1A/GA733 Antigen and Its Murine Homologue

1998 • 77 citations

Induction of antigen-specific T and B cell immunity in colon carcinoma patients by anti-idiotypic antibody.

1995 • 74 citations

Baculovirus recombinant expressing a secreted form of a transmembrane carcinoma-associated antigen.

1992 • 71 citations

Isolation and characterization of a carcinoma-associated antigen

1986 • 71 citations

Intracranial Administration of Adenovirus Expressing HSV-TK in Combination with Ganciclovir Produces a Dose-Dependent, Self-Limiting Inflammatory Response

1997 • 61 citations

Immunomodulatory Activity of Monoclonal Anti-Idiotypic Antibody to Anti-Colorectal Carcinoma Antibody CO17–1A in Animals and Patients

1994 • 54 citations

Induction of specific immunity to human colon carcinoma by anti‐idiotypic antibodies to monoclonal antibody CO17‐1A

1987 • 51 citations

An Adenovirus Recombinant that Expresses the Human Cytomegalovirus Major Envelope Glycoprotein and Induces Neutralizing Antibodies

1990 • 48 citations

Preparation and characterization of a polyvalent human melanoma antigen vaccine.

1986 • 47 citations

Anti-idiotype cancer vaccines: pre-clinical and clinical studies.

1991 • 47 citations

Human colorectal cancer (CRC) antigen CO17-1A/GA733 encoded by adenovirus inhibits growth of established CRC cells in mice.

1997 • 45 citations

Immunogenicity of human melanoma-associated antigens defined by murine monoclonal antibodies in allogeneic and xenogeneic hosts.

1987 • 37 citations

Structure, Function, and Clinical Significance of Human Tumor Antigens

1990 • 36 citations

Ex vivo perfusion of a tumor-containing colon with monoclonal antibody

1981 • 33 citations

Ex vivo perfusion of human colon with monoclonal anticolorectal cancer antibodies

1982 • 32 citations

The molecular basis of cancer immunotherapy by cytotoxic T lymphocytes

1998 • 28 citations

Immune response to tumor antigens in a patient with colorectal cancer after immunization with anti-idiotype antibody

1992 • 26 citations

Biological therapy: approaches in colorectal cancer

1998 • 21 citations

Harnessing T-lymphocytes for human cancer immunotherapy

1985 • 20 citations

Untitled

1998 • 19 citations

Monoclonal anti-idiotypic antibody functionally mimics the human gastrointestinal carcinoma epitope GA733

1996 • 18 citations

Expression of an antigen homologous to the human CO17-1A/GA733 colon cancer antigen in animal tissues

1997 • 17 citations

Induction of immunity to colon carcinoma antigen CO17-1A by monoclonal anti-idiotype (Ab2) : effects of Ab2 fragmentation, carrier and adjuvant

1996 • 15 citations

Idiotypic intramolecular help. Induction of tumor-specific antibodies by monoclonal anti-idiotypic antibody with the help of Fc-specific T helper clones.

1989 • 14 citations

Low Doses of 105AD7 Cancer Vaccine Preferentially Stimulate Anti-Tumor T-Cell Immunity

1997 • 14 citations

Therapeutic vaccines for melanoma: progress and problems

1996 • 10 citations

Anti-Idiotypic Antibodies In Cancer Therapy

2018 • 7 citations

Monoclonal Antibodies as Applied to Tumor-Associated Antigens: The CO 17-1A Antigen

2020 • 3 citations