Carbohydrate vaccines that induce antibodies against cancer. 1. Rationale

Biological roles of oligosaccharides: all of the theories are correct

1993 • 5,121 citations

Carbohydrate-Specific Receptors of the Liver

1982 • 1,895 citations

T and Tn, General Carcinoma Autoantigens

1984 • 998 citations

Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism.

1996 • 985 citations

Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma

1994 • 647 citations

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

1996 • 581 citations

Mouse monoclonal IgG3 antibody detecting GD3 ganglioside: a phase I trial in patients with malignant melanoma.

1985 • 566 citations

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

1995 • 552 citations

The Protective Level of Serum Antibodies to the Capsular Polysaccharide of Haemophilus influenzae Type b

1983 • 540 citations

Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside.

1994 • 522 citations

Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies

1993 • 501 citations

The selectins and their ligands

1994 • 478 citations

Ganglioside GD2 specific monoclonal antibody 3F8: a phase I study in patients with neuroblastoma and malignant melanoma.

1987 • 404 citations

Structures and functions of the sugar chains of glycoproteins

1992 • 403 citations

Cancer immunology: the search for specificity--G. H. A. Clowes Memorial lecture.

1981 • 395 citations

Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients

1990 • 380 citations

A Randomized, Prospective Field Trial of a Conjugate Vaccine in the Protection of Infants and Young Children against InvasiveHaemophilus influenzaeType b Disease

1990 • 335 citations

gamma/delta and other unconventional T lymphocytes: what do they see and what do they do?

1996 • 306 citations

Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group-related antigens

1997 • 292 citations

THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS

1923 • 281 citations

Selection of tumor antigens as targets for immune attack using immunohistochemistry: I. Focus on gangliosides

1997 • 279 citations

Epidermal Growth Factor Receptor Gene Expression in Estrogen Receptor-Positive and Negative Human Breast Cancer Cell Lines

1987 • 274 citations

Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity, and the brain.

1996 • 273 citations

Induction of autoreactive B cells allows priming of autoreactive T cells.

1991 • 253 citations

Cancer immunology: the search for specificity.

1982 • 226 citations

Regression of cutaneous metastatic melanoma by intralesional injection with human monoclonal antibody to ganglioside GD2.

1986 • 220 citations

Differential E-selectin-dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials.

1994 • 218 citations

T cell recognition of carbohydrates on type II collagen.

1994 • 206 citations

Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells.

1984 • 198 citations

Glycosylation

1992 • 186 citations

Recognition of carbohydrate by major histocompatibility complex class I-restricted, glycopeptide-specific cytotoxic T lymphocytes.

1994 • 184 citations

Antibodies Against Mucin-Associated Sialyl-Tn Epitopes Correlate with Survival of Metastatic Adenocarcinoma Patients Undergoing Active Specific Immunotherapy with Synthetic STn Vaccine

1996 • 184 citations

THE RESULTS OF THE SERUM TREATMENT IN THIRTEEN HUNDRED CASES OF EPIDEMIC MENINGITIS

1913 • 179 citations

MHC interaction and T cell recognition of carbohydrates and glycopeptides.

1992 • 171 citations

Immunogenicity of melanoma‐associated gangliosides in cancer patients

1985 • 168 citations

Immunologic Rejection of Human Cancer Transplanted with a Renal Allograft

1968 • 168 citations

Philip Levine Award Lecture: Blood Group Antigens as Markers for Normal Differentiation and Malignant Change in Human Tissues

1987 • 167 citations

Active specific immunotherapy of a murine mammary adenocarcinoma using a synthetic tumor-associated glycoconjugate.

1990 • 165 citations

Approaches to Augmenting the Immunogenicity of Melanoma Gangliosides: From Whole Melanoma Cells to Ganglioside‐KLH Conjugate Vaccines

1995 • 161 citations

Gangliosides of Human Melanoma2

1987 • 161 citations

Ganglioside expression on human malignant melanoma assessed by quantitative immune thin‐layer chromatography

1993 • 154 citations

Phase I trial of the murine monoclonal anti-GD2 antibody 14G2a in metastatic melanoma.

1992 • 151 citations

Major histocompatibility proteins, anti-Hu antibodies, and paraneoplastic encephalomyelitis in neuroblastoma and small cell lung cancer

1995 • 144 citations

Induction of alpha-N-acetylgalactosamine-O-serine/threonine (Tn) antigen-mediated cellular immune response for active immunotherapy in mice.

1991 • 132 citations

Prolonged Survival for Melanoma Patients With Elevated IgM Antibody to Oncofetal Antigen<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1981 • 126 citations

Immunoscintigraphy performed with In-111-labeled CYT-103 in the management of colorectal cancer: comparison with CT.

1992 • 124 citations

Characterization of IgG and IgM antibodies induced in melanoma patients by immunization with purified GM2 ganglioside.

1989 • 122 citations

The Sialoadhesins ? A family of sialic acid-dependent cellular recognition molecules within the immunoglobulin superfamily

1996 • 118 citations

Individually distinct transplantation antigens of chemically induced mouse tumors

1988 • 113 citations

Universal hepatitis B immunization

1992 • 111 citations

Immunogenicity of synthetic TF-KLH (keyhole limpet hemocyanin) and sTn-KLH conjugates in colorectal carcinoma patients

1995 • 103 citations

Total Synthesis of a Human Breast Tumor Associated Antigen

1995 • 100 citations

Antibodies Against Autologous Tumor Cell Proteins in Patients With Small-Cell Lung Cancer: Association With Improved Survival

1993 • 100 citations

Polysialic acid of the neural cell adhesion molecule distinguishes small cell lung carcinoma from carcinoids.

1991 • 98 citations

Rabies

1993 • 98 citations

Universal Hepatitis B Immunization

1992 • 90 citations

Immunization of Mice with a Fully Synthetic Globo H Antigen Results in Antibodies against Human Cancer Cells: A Combined Chemical—Immunological Approach to the Fashioning of an Anticancer Vaccine

1997 • 86 citations

GANGLIOSIDE GD(2) EXPRESSION IN THE HUMAN NERVOUS-SYSTEM AND IN NEUROBLASTOMAS - AN IMMUNOHISTOCHEMICAL STUDY

1993 • 85 citations

TRANSPLANTED CARCINOMA IN AN IMMUNOSUPPRESSED PATIENT

1970 • 84 citations

Detection of a ganglioside antigen associated with small cell lung carcinomas using monoclonal antibodies directed against fucosyl-GM1.

1986 • 80 citations

Immunogenicity of synthetic conjugates of Lewis y oligosaccharide with proteins in mice: towards the design of anticancer vaccines

1998 • 58 citations

Human Melanoma Cell Lines Deficient in GD3 Ganglioside Expression Exhibit Altered Growth and Tumorigenic Characteristics

1996 • 50 citations

Differential recognition of murine tumor-associated oncofetal transplantation antigen and individually specific tumor transplantation antigens by syngeneic cloned BALB/c and RFM mouse T cells.

1994 • 23 citations

Ganglioside conjugate vaccines

1994 • 23 citations

Specific Immunotherapy of Cancer With Vaccines

1993 • 20 citations

FC-2.15, a monoclonal antibody active against human breast cancer, specifically recognizes Lewis x hapten

1998 • 20 citations

Phase I Clinical Trial in Cancer Patients of a New Monoclonal Antibody FC-2.15 Reacting with Tumor Proliferating Cells

1995 • 17 citations

Coexpression of GD3Ganglioside with CD45RO in Resting and Activated Human T Lymphocytes

1996 • 17 citations

American Academy of Pediatrics Committee on Infectious Diseases: Universal hepatitis B immunization.

1992 • 12 citations

T lymphocyte heterogeneity in the rat

1990 • 11 citations

Deleted Work

1955 • 0 citations