Voltage-and frequency-dependent block of diltiazem on the slow inward current and generation of tension in frog ventricular muscle

Comparative pharmacology of calcium antagonists: Nifedipine, verapamil and diltiazem

1980 • 865 citations

The effect of the cardiac membrane potential on the rapid availability of the sodium‐carrying system

1955 • 763 citations

THE INFLUENCE OF THE INTERVAL BETWEEN BEATS ON MYOCARDIAL CONTRACTILITY.

1963 • 569 citations

CALCIUM‐INDUCED RELEASE OF CALCIUM FROM THE SARCOPLASMIC RETICULUM OF SKINNED CELLS FROM ADULT HUMAN, DOG, CAT, RABBIT, RAT, AND FROG HEARTS AND FROM FETAL AND NEW‐BORN RAT VENTRICLES*

1978 • 469 citations

Existence and role of a slow inward current during the frog atrial action potential

1969 • 449 citations

Membrane calcium current in ventricular myocardial fibres

1970 • 401 citations

The effect of the internal sodium concentration on calcium fluxes in isolated guinea‐pig auricles

1970 • 328 citations

Excitation-contraction coupling in heart muscle: Membrane control of development of tension

1973 • 304 citations

Inotropic and electrophysiological actions of verapamil and D 600 in mammalian myocardium

1975 • 258 citations

Comparative effects of three calcium antagonists, diltiazem, verapamil and nifedipine, on the sinoatrial and atrioventricular nodes. Experimental and clinical studies.

1981 • 256 citations

Calcium‐activated transient outward current in calf cardiac Purkinje fibres.

1980 • 237 citations

Existence of two transient outward currents in sheep cardiac Purkinje fibers

1982 • 223 citations

The ionic nature of slow inward current and its relation to contraction

1972 • 191 citations

Structures of physiological interest in the frog heart ventricle

1972 • 190 citations

Sodium-calcium exchange in regulation of cardiac contractility. Evidence for an electrogenic, voltage-dependent mechanism.

1979 • 185 citations

Effect of Diltiazem on Electrical and Mechanical Activity of Isolated Cardiac Ventricular Muscle of Guinea Pig

1975 • 181 citations

The voltage- and time-dependent effects of (-)-verapamil on the slow inward current in isolated cat ventricular myocardium.

1978 • 176 citations

Inotropic and electrophysiological actions of verapamil and D600 in mammalian myocardium

1975 • 174 citations

Calcium conductance and tension in mammalian ventricular muscle

1975 • 164 citations

Selective inhibition of the transmembrane Ca conductivity of mammalian myocardial fibres by Ni, Co and Mn ions

1973 • 157 citations

Excitation—contraction coupling in frog ventricle: evidence from voltage clamp studies

1971 • 139 citations

Comparative clinical electrophysiologic effects of diltiazem, verapamil and nifedipine: A review

1983 • 132 citations

Regional contractility. Selective depression of ischemic myocardium by verapamil.

1976 • 123 citations

On the mechanism of slow calcium channel block in heart

1980 • 119 citations

On the mechanism underlying the action of D-600 on slow inward current and tension in mammalian myocardium.

1977 • 116 citations

Calcium channel block and recovery from block in mammalian ventricular muscle treated with organic channel inhibitors

1982 • 112 citations

Slow inward current and contraction of sheep cardiac Purkinje fibers.

1975 • 101 citations

Calcium-mediated action potentials in mammalian myocardium

1973 • 85 citations

Diltiazem and verapamil preferentially block inactivated cardiac calcium channels

1983 • 80 citations

Studies on the inhibitory effect of verapamil on the slow inward current in mammalian ventricular myocardium

1978 • 78 citations

Pharmacological studies on a new l,5-benzothiazepine derivative (CRD-401).

1971 • 75 citations

A study of the effect of the rate of stimulation on the transient outward current in sheep cardiac Purkinje fibres.

1981 • 64 citations

Electrophysiologic Effects of Diltiazem, a New Slow Channel Inhibitor, on Canine Cardiac Fibers

1977 • 63 citations

Calcium‐sodium antagonism on the frog's heart: a voltage‐clamp study.

1976 • 63 citations

A Dissociation of Positive Staircase (Bowditch) from Ouabain-Induced Positive Inotropism

1974 • 56 citations

Calcium conductance in relation to contractility in frog myocardium.

1976 • 55 citations

The interaction of sodium and calcium ions at the cell membrane and the control of contractile strength in frog atrial muscle.

1980 • 55 citations

Electrophysiologic Effects of Diltiazem, a Calcium Antagonist, in Patients With Impaired Sinus or Atrioventricular Node Function

1980 • 49 citations

Electrical and Mechanical Responses to Diltiazem in Potassium Depolarized Myocardium of the Guinea Pig

1976 • 47 citations

Measurement of transmembrane potential and current in cardiac muscle: a new voltage clamp method.

1977 • 43 citations

Ionic events responsible for the cardiac resting and action potential

1982 • 38 citations

Inhibitory activity of blockers of the slow inward current in rat myocardium, a study in steady state and of rate of action

1980 • 37 citations

The effects of diltiazem hydrochloride on the cardiac conduction: A clinical study of His bundle electrogram.

1978 • 33 citations

Voltage Clamp Studies of the Slow Inward Current

1980 • 29 citations

Effect of diltiazem on calcium transport and development of tension in heart muscle.

1982 • 22 citations

The influence of resting membrane potential on the effect of verapamil on atria

1980 • 15 citations

Intrinsic Birefringence Signal Preceding the Onset of Contraction in Heart Muscle

1981 • 9 citations

A Ca-TRANSPORT SYSTEM FOR ACTIVATION OF TENSION IN FROG VENTRICULAR MUSCLE

1978 • 6 citations

The Role of the Slow Inward Current in Impulse Formation

1980 • 6 citations