Copolymer 1 inhibits experimental autoimmune uveoretinitis

A Pilot Trial of Cop 1 in Exacerbating–Remitting Multiple Sclerosis

1987 • 465 citations

A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens.

1988 • 451 citations

Suppression of experimental allergic encephalomyelitis by a synthetic polypeptide

1971 • 431 citations

Ocular Infection and Immunity

1996 • 425 citations

Copolymer 1 induces T cells of the T helper type 2 that crossreact with myelin basic protein and suppress experimental autoimmune encephalomyelitis

1997 • 280 citations

Direct binding of myelin basic protein and synthetic copolymer 1 to class II major histocompatibility complex molecules on living antigen-presenting cells--specificity and promiscuity.

1994 • 243 citations

Treatment of multiple sclerosis with Copolymer-1 (Copaxone®): implicating mechanisms of Th1 to Th2/Th3 immune-deviation

1998 • 226 citations

Pathology of experimental autoimmune uveoretinitis in mice

1990 • 199 citations

A placebo‐controlled, double‐blind, randomized, two‐center, pilot trial of Cop 1 in chronic progressive multiple sclerosis

1991 • 176 citations

Bystander suppression of experimental autoimmune encephalomyelitis by T cell lines and clones of the Th2 type induced by copolymer 1

1998 • 176 citations

Copolymer 1 inhibits chronic relapsing experimental allergic encephalomyelitis induced by proteolipid protein (PLP) peptides in mice and interferes with PLP-specific T cell responses

1996 • 155 citations

Suppression of experimental allergic encephalomyelitis in rhesus monkeys by a synthetic basic copolymer

1974 • 127 citations

The development of Cop 1 (Copaxone®), and innovative drug for the treatment of multiple sclerosis: personal reflections

1996 • 94 citations

FUNCTIONAL PROPERTIES OF INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN

1991 • 90 citations

Copolymer-1-induced inhibition of antigen-specific T cell activation: interference with antigen presentation

1992 • 81 citations

Autoimmunity in the eye and its regulation

1994 • 74 citations

Binding Motifs of Copolymer 1 to Multiple Sclerosis- and Rheumatoid Arthritis-Associated HLA-DR Molecules

1999 • 57 citations

Oral tolerance with Copolymer 1 for the treatment of multiple sclerosis

1999 • 50 citations

Myelin basic protein specific T-helper cells induce experimental anterior uveitis

1996 • 47 citations

T cell immunity to myelin basic protein induces anterior uveitis in Lewis rats

1994 • 43 citations

Uveitis and Retinal Vasculitis in Acute Experimental Allergic Encephalomyelitis in the Lewis Rat: An Ultrastructural Study

1993 • 29 citations

EAE TCR Motifs and Antigen Recognition in Myelin Basic Protein-Induced Anterior Uveitis in Lewis Rats

1998 • 21 citations

Immune responses to peptides derived from the retinal protein IRBP: Immunopathogenic determinants are not necessarily immunodominant

1989 • 18 citations

[Treatment of multiple sclerosis].

1999 • 11 citations