Back to search

The effect of the anticancer drugs tamoxifen and hydroxytamoxifen on the calcium pump of isolated sarcoplasmic reticulum vesicles

Data up to Jan 2025

Published1996
Citations25
References54

Total Citations Per Year

Abstract

References (54)

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

1949 • 16,078 citations

The Enzymes of Biological Membranes

1985 • 1,362 citations

Inhibition of protein kinase C by tamoxifen.

1985 • 464 citations

Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice.

1985 • 396 citations

Tamoxifen and metabolites in MCF7 cells: correlation between binding to estrogen receptor and inhibition of cell growth.

1982 • 393 citations

Potential Role of Tamoxifen in Prevention of Breast Cancer

1991 • 387 citations

Distribution of tamoxifen and its metabolites in rat and human tissues during steady-state treatment.

1991 • 361 citations

High-affinity anti-oestrogen binding site distinct from the oestrogen receptor

1980 • 360 citations

Tamoxifen is a calmodulin antagonist in the activation of cAMP phosphodiesterase

1984 • 296 citations

The reversibility of the sarcoplasmic calcium pump

1978 • 222 citations

The Effect of Calcium Ionophores on Fragmented Sarcoplasmic Reticulum

1972 • 215 citations

Triphenylethylenes: A New Class of Protein Kinase C Inhibitors

1986 • 138 citations

Inhibition of protein kinase C mediated signal transduction by tamoxifen

1986 • 131 citations

Cytochrome P-450-mediated activation and irreversible binding of the antiestrogen tamoxifen to proteins in rat and human liver: possible involvement of flavin-containing monooxygenases in tamoxifen activation.

1991 • 121 citations

Long-term adjuvant tamoxifen therapy for breast cancer

1990 • 117 citations

Caclium uptake and associated adenosine triphosphatase activity in fragmented sarcoplasmic reticulum. Requirement for potassium ions.

1977 • 99 citations

Tamoxifen and hydroxytamoxifen as intramembraneous inhibitors of lipid peroxidation. Evidence for peroxyl radical scavenging activity

1994 • 95 citations

The anticancer drug tamoxifen induces changes in the physical properties of model and native membranes

1993 • 89 citations

Ca2(+)-dependent binding of tamoxifen to calmodulin isolated from bovine brain.

1990 • 88 citations

A rapid and ultrasensitive method to measure Ca++ movements across biological membranes

1975 • 80 citations

Fast efflux of Ca2+ mediated by the sarcoplasmic reticulum Ca2(+)-ATPase.

1991 • 78 citations

The antioxidant action of tamoxifen and its metabolites Inhibition of lipid peroxidation

1990 • 77 citations

Role of Specific Interactions Between Protein Kinase C and Triphenylethylenes in Inhibition of the Enzyme

1988 • 75 citations

Uncoupling of Ca2+ transport in sarcoplasmic reticulum as a result of labeling lipid amino groups and inhibition of Ca2+-ATPase activity by modification of lysine residues of the Ca2+-ATPase polypeptide.

1982 • 67 citations

A reliable and rapid procedure to estimate drug partitioning in biomembranes

1991 • 66 citations

Proton gradient formation during transport of Ca2+ by sarcoplasmic reticulum

1978 • 65 citations

Fluidity of sarcoplasmic reticulum membranes investigated with dipyrenylpropane, an intramolecular excimer probe

1982 • 64 citations

Detection of an initial burst of Ca2+ translocation in sarcoplasmic reticulum

1977 • 63 citations

Functional evidence of a transmembrane channel within the Ca2+ transport ATPase of sarcoplasmic reticulum

1992 • 56 citations

Ca(2+)-dependent and thapsigargin-inhibited phosphorylation of Na+,K(+)-ATPase catalytic domain following chimeric recombination with Ca(2+)-ATPase.

1993 • 53 citations

Localization of a Mg2+- or Ca2+-activated (“basic”) ATPase in skeletal muscle

1979 • 50 citations

Reversal of P-glycoprotein-mediated multidrug resistance by pure anti-oestrogens and novel tamoxifen derivatives

1994 • 46 citations

The active metabolite hydroxytamoxifen of the anticancer drug tamoxifen induces structural changes in membranes

1993 • 45 citations

Effect of short-chain primary alcohols on fluidity and activity of sarcoplasmic reticulum membranes

1986 • 43 citations

A fast passive Ca2+ efflux mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles

1987 • 41 citations

Cholesterol in sarcoplasmic reticulum and the physiological significance of membrane fluidity

1981 • 40 citations

Molecular mechanism of calcium-ATPase activation by halothane in sarcoplasmic reticulum

1993 • 39 citations

The arsenate induced calcium release from sarcoplasmic vesicles

1972 • 36 citations

Functional interactions of catalytic site and transmembrane channel in the sarcoplasmic reticulum ATPase.

1990 • 34 citations

Modulation of sarcoplasmic reticulum calcium pump activity by membrane fluidity

1984 • 33 citations

The Ca2+ permeability of sarcoplasmic reticulum vesicles I. Ca2+ outflow in the non-energized state of the calcium pump

1983 • 32 citations

The effect of lipid peroxidation on the calcium-accumulating ability of the microsomal fraction isolated from chicken breast muscle

1978 • 31 citations

Speculation on the mechanism of action of triphenylethylene antioestrogens

1994 • 31 citations

Local anesthetics induce fast Ca2+ efflux through a nonenergized state of the sarcoplasmic reticulum Ca(2+)-ATPase.

1992 • 28 citations

The Ca2+ permeability of sarcoplasmic reticulum vesicles II. Ca2+ efflux in the energized state of the calcium pump

1983 • 26 citations

A model for the uptake and release of Ca2+ by sarcoplasmic reticulum

1987 • 26 citations

Nonsteroidal antiestrogen inhibition of protein kinase C in human corpus luteum and placenta

1989 • 21 citations

Kinetic Regulation of Catalytic and Transport Activities in Sarcoplasmic Reticulum ATPase

1985 • 21 citations

Antiestrogen action in mammary cancer and in fetal cells

1990 • 19 citations

Interactions of tamoxifen in the chicken

1987 • 16 citations

Oxalate transfer across the membranes of sarcoplasmic reticulum during the uptake of Ca++

1982 • 16 citations

Thermal Uncoupling of the Ca2+‐transporting ATPase in Sarcoplasmic Reticulum

1994 • 14 citations

Tamoxifen binding sites heterogeneity in breast cancer: a comparative study with steroid hormone receptors

1991 • 13 citations

An immobilized antiestrogen binds a specific uterine protein in addition to estrogen receptor proteins

1984 • 12 citations

Cited By (0)

Loading...
The effect of the anticancer drugs tamoxifen and hydroxytamoxifen on the calcium pump of… (1996) – Toxicology in Vitro | Metascience Observatory Explorer