New models of focal cerebral ischaemia.

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Reversible middle cerebral artery occlusion without craniectomy in rats.

1989 • 6,875 citations

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

1986 • 2,584 citations

A new model of bilateral hemispheric ischemia in the unanesthetized rat.

1979 • 1,934 citations

Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

1987 • 1,821 citations

Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion

1981 • 1,420 citations

Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats.

1986 • 1,257 citations

Induction of reproducible brain infarction by photochemically initiated thrombosis

1985 • 1,092 citations

Experimental studies of ischemic brain edema

1986 • 932 citations

Experimental studies of ischemic brain edema : a new experimental study of ischemic brain edema : 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area

1986 • 770 citations

Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model

1984 • 741 citations

Rodent models of cerebral ischemia.

1989 • 663 citations

A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction.

1986 • 588 citations

The glutamate antagonist MK‐801 reduces focal ischemic brain damage in the rat

1988 • 547 citations

Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion.

1989 • 516 citations

Focal Brain Ischemia in the Rat: Methods for Reproducible Neocortical Infarction Using Tandem Occlusion of the Distal Middle Cerebral and Ipsilateral Common Carotid Arteries

1988 • 488 citations

The Quantification of Cerebral Infarction following Focal Ischemia in the Rat: Influence of Strain, Arterial Pressure, Blood Glucose Concentration, and Age

1988 • 393 citations

Pathogenetic similarity of strokes in stroke-prone spontaneously hypertensive rats and humans.

1976 • 372 citations

Endothelin 1, an endothelium-derived peptide, is expressed in neurons of the human spinal cord and dorsal root ganglia.

1989 • 349 citations

Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia.

1991 • 325 citations

Focal Cerebral Ischaemia in the Rat: 2. Regional Cerebral Blood Flow Determined by [¹⁴C]Iodoantipyrine Autoradiography following Middle Cerebral Artery Occlusion

1981 • 306 citations

Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia.

1987 • 302 citations

Effect of experimental cerebral infarction in rat brain on catecholamines and behaviour

1975 • 245 citations

Endothelin and the production of cerebral vasospasm in dogs

1989 • 188 citations

Middle cerebral artery occlusion: correlation of computed tomography and angiography with clinical outcome.

1987 • 176 citations

Neuropeptide Y: Immunocytochemical localization to and effect upon feline pial arteries and veins in vitro and in situ

1984 • 159 citations

Ischemic brain damage in a model of acute subdural hematoma

1990 • 152 citations

Nimodipine and the Haemodynamic and Histopathological Consequences of Middle Cerebral Artery Occlusion in the Rat

1986 • 147 citations

Correlation between rCBF and histological changes following temporary middle cerebral artery occlusion.

1980 • 144 citations

Cerebral microvessel endothelium is producing endothelin

1990 • 143 citations

Endothelin acts in feline and canine cerebral arteries from the adventitial side.

1989 • 138 citations

Recirculation model following MCA occlusion in rats

1985 • 137 citations

Ischemic Brain Damage in a Model of Acute Subdural Hematoma

1990 • 131 citations

Reduction of local cerebral blood flow to pathological levels by endothelin-1 applied to the middle cerebral artery in the rat

1990 • 115 citations

The topography of impaired micro vascular perfusion in the primate brain following total circulatory arrest

1972 • 115 citations

Cerebral Ischemia

1968 • 101 citations

Recombinant human tissue-type plasminogen activator therapy in acute thromboembolic stroke

1987 • 96 citations

A new model of embolic stroke produced by photochemical injury to the carotid artery in the rat

1988 • 74 citations

Pure cortical ischemia versus striatal ischemia. Circulatory, metabolic, and neuropathologic consequences

1985 • 72 citations

Contractile Responses to Endothelin in Feline Cortical Vessels in situ

1990 • 69 citations

A model for quantitative evaluation of embolic stroke therapy

1987 • 69 citations

The Merck Manual of Diagnosis and Therapy

1982 • 66 citations

The effects of dizocilpine (MK-801), phencyclidine, and nimodipine on infarct size 48 h after middle cerebral artery occlusion in the rat

1991 • 65 citations

The effect of the kappa-opioid receptor agonist CI-977 in a rat model of focal cerebral ischaemia

1992 • 59 citations

Animal Models for the Study of Drugs in Ischemic Stroke

1989 • 58 citations

Morphological consequences of early reperfusion following thrombotic or mechanical occlusion of the rat middle cerebral artery

1989 • 48 citations

Clinical relevance of models of cerebral ischemia.

1979 • 47 citations

Effects of intracisternal endothelin-1 injection on blood flow to the lower brain stem

1991 • 40 citations

CEREBRAL BLOOD FLOW: PHYSIOLOGIC AND CLINICAL ASPECTS

1988 • 38 citations

A transbasisphenoidal approach for selective occlusion of the middle cerebral artery in rats

1980 • 22 citations

Experimental studies of ischemic brain edema. Effect of recirculation of the blood flow after ischemia on post-ischemic brain edema.

1989 • 11 citations

The Founders of Neurology

1972 • 8 citations