Increased matrix metalloproteinases 2 and 9 in placenta of diabetic rats at midgestation

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

1996 • 5,498 citations

S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

1996 • 1,604 citations

Matrix metalloproteinases: effectors of development and normal physiology

2000 • 1,236 citations

Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species

1998 • 1,024 citations

S-Nitrosylation of Matrix Metalloproteinases: Signaling Pathway to Neuronal Cell Death

2002 • 943 citations

Multiple pathways of peroxynitrite cytotoxicity

2003 • 505 citations

Genes, Development and Evolution of the Placenta

2003 • 348 citations

Expression and function of matrix metalloproteinases and their inhibitors at the maternal-embryonic boundary during mouse embryo implantation

1996 • 345 citations

Implantation and decidualization in rodents

1993 • 329 citations

Metabolic adaptations in pregnancy and their implications for the availability of substrates to the fetus

2000 • 329 citations

Matrix metalloproteinases: old dogs with new tricks.

2003 • 293 citations

Expression of Matrix Metalloproteinase (MMP)-2 and MMP-9 in Human Placenta and Fetal Membranes in Relation to Preterm and Term Labor

2002 • 229 citations

Activation of Human Neutrophil Procollagenase by Nitrogen Dioxide and Peroxynitrite: A Novel Mechanism for Procollagenase Activation Involving Nitric Oxide

1997 • 226 citations

The Matrix Metalloproteinase Family

1998 • 225 citations

Purification and properties of a small latent matrix metalloproteinase of the rat uterus.

1988 • 220 citations

Measurement of nitrite and nitrate levels in plasma and urine — what does this measure tell us about the activity of the endogenous nitric oxite system?

1998 • 213 citations

Altered Placental Oxidative Stress Status in Gestational Diabetes Mellitus

2003 • 204 citations

Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes

1979 • 200 citations

Evidence that elevated glucose causes altered gene expression, apoptosis, and neural tube defects in a mouse model of diabetic pregnancy.

1999 • 195 citations

Matrix metalloproteinases in normal menstruation

1996 • 180 citations

Increased matrix metalloproteinase activity and reduced tissue inhibitor of metalloproteinases-1 levels in amniotic fluids from pregnancies complicated by premature rupture of membranes

1996 • 176 citations

TGF-β Plays a Key Role in Morphogenesis of the Pancreatic Islets of Langerhans by Controlling the Activity of the Matrix Metalloproteinase MMP-2

1998 • 174 citations

Accelerated apoptosis in the Timp-3–deficient mammary gland

2001 • 164 citations

Nitric oxide synthase type I and type III gene expression are developmentally regulated in rat lung

1994 • 156 citations

Congenital malformations in offspring of diabetic mothers--animal and human studies.

2003 • 156 citations

Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the mouse uterus during the peri-implantation period

1997 • 154 citations

Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch

1997 • 151 citations

Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells

2000 • 146 citations

Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia

2000 • 140 citations

Increased Level of Matrix Metalloproteinases 2 and 9 in the Ripening Process of the Human Cervix1

2002 • 139 citations

MT1-MMP–dependent, apoptotic remodeling of unmineralized cartilage

2003 • 131 citations

Production and Activation of Matrix Metalloproteinase-2 in Proliferative Diabetic Retinopathy

2003 • 121 citations

Malformations in offspring of diabetic rats: Morphometric analysis of neural crest-derived organs and effects of maternal vitamin E treatment

2000 • 97 citations

A null mutation for Tissue Inhibitor of Metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis

2003 • 95 citations

Activation of the Mitogen Activated Protein Kinase Extracellular Signal-Regulated Kinase 1 and 2 by the Nitric Oxide–cGMP–cGMP-Dependent Protein Kinase Axis Regulates the Expression of Matrix Metalloproteinase 13 in Vascular Endothelial Cells

2002 • 92 citations

Regulation of matrix metalloproteinase-9 in endometrium during the menstrual cycle and following administration of intrauterine levonorgestrel

1999 • 89 citations

Elevated matrix metalloproteinase-2 and -3 production from human diabetic dermal fibroblasts

2003 • 84 citations

Diminished Matrix Metalloproteinase 2 (MMP-2) in Ectomesenchyme-Derived Tissues of the Patch Mutant Mouse: Regulation of MMP-2 by PDGF and Effects on Mesenchymal Cell Migration

1999 • 79 citations

A functional overlap of plasminogen and MMPs regulates vascularization during placental development

2003 • 72 citations

Coordinated and Cell-Specific Regulation of Membrane Type Matrix Metalloproteinase 1 (MT1-MMP) and Its Substrate Matrix Metalloproteinase 2 (MMP-2) by Physiological Signals during Follicular Development and Ovulation

1998 • 69 citations

MMP-9 (gelatinase B) mRNA is expressed during mouse neurogenesis and may be associated with vascularization

1995 • 67 citations

Developmental expression of MMP‐9 (gelatinase B) mRNA in mouse embryos

1995 • 65 citations

Distribution of the endothelial constitutive nitric oxide synthase in the developing rat brain: an immunohistochemical study

1998 • 60 citations

Experimental Diabetes and the Lung: I. Changes in Growth, Morphometry, and Biochemistry

1988 • 58 citations

Regulation of metalloproteinases by nitric oxide in human trophoblast cells in culture

2001 • 56 citations

Abnormal Organogenesis in Salivary Gland Development May Initiate Adult Onset of Autoimmune Exocrinopathy

2001 • 55 citations

Nitric oxide increases matrix metalloproteinase-1 production in human uterine cervical fibroblast cells

2001 • 52 citations

Dysmorphogenic effects of nitric oxide (NO) and NO‐synthase inhibition: Studies with intra‐amniotic injections of sodium nitroprusside and N^G‐monomethyl‐L‐arginine

1994 • 51 citations

Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation

1999 • 50 citations

In vitro Migration of Cytotrophoblasts Through a Decidual Endothelial Cell Monolayer: The Role of Matrix Metalloproteinases

2003 • 49 citations

Review articles

1998 • 49 citations

Involvement of matrix metalloproteinases 2 and 9, tissue inhibitor of metalloproteinases and apoptosis in tissue remodelling in the sheep placenta

2000 • 48 citations

Identification of 72-kilodalton type IV collagenase at sites of trophoblastic invasion of macaque spiral arteries

1994 • 42 citations

Pre-eclampsia (EPH-gestosis)-induced decrease of MMP-s content in the umbilical cord artery

2003 • 42 citations

Membrane-type matrix metalloproteinase-9 activity in placental tissue from patients with pre-existing and gestational diabetes mellitus

2000 • 42 citations

Embryogenesis of the rat heart: the expression of collagenases

2002 • 37 citations

Nitric oxide induces gelatinase A (matrix metalloproteinase 2) during rat embryo implantation

2002 • 36 citations

Nitrotyrosine Immunostaining Correlates with Increased Extracellular Matrix: Evidence of Postplacental Hypoxia

2001 • 34 citations

Reduced expression of tissue inhibitor of metalloproteinase (TIMP)-2 in gestational trophoblastic diseases

2002 • 34 citations

Limb Reduction Defects after Prenatal Inhibition of Nitric Oxide Synthase in Rats

1995 • 33 citations

Experimental Diabetes and the Lung

1988 • 25 citations

Increased prostaglandin E generation and enhanced nitric oxide synthase activity in the non-insulin-dependent diabetic embryo during organogenesis

1998 • 20 citations

Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat

1998 • 15 citations

Metalloproteinase 2 activity and modulation in uterus from neonatal streptozotocin-induced diabetic rats during embryo implantation

2002 • 14 citations

Influence of maternal diabetes on basement membranes, type 2 cells, and capillaries in the developing rat lung

1984 • 12 citations

Occurrence and distribution of matrix metalloproteinase-2-immunoreactivity in human embryonic tissues.

1995 • 11 citations

Levels of endothelin-1 in embryos from control and neonatal streptozotocin-induced diabetic rats, and their relationship with nitric oxide generation

2002 • 5 citations

Nitric oxide mediates increased prostaglandin E production by oocyte - cumulus complexes in the non-insulin-dependent diabetic rat

1998 • 4 citations