Back to search

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene.

Data up to Jan 2025

Published1996
Citations559
References45

Total Citations Per Year

Abstract

References (45)

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

1961 • 3,860 citations

Increased Plasma Levels of a Rapid Inhibitor of Tissue Plasminogen Activator in Young Survivors of Myocardial Infarction

1985 • 1,364 citations

Physiological consequences of loss of plasminogen activator gene function in mice

1994 • 1,051 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane.

1981 • 587 citations

Alterations of the Gas Exchange Apparatus in Adult Respiratory Insufficiency Associated with Septicemia1,2

1977 • 551 citations

The pathogenesis of bleomycin-induced pulmonary fibrosis in mice.

1974 • 469 citations

An Immunohistochemical Study of Architectural Remodeling and Connective Tissue Synthesis in Pulmonary Fibrosis

1989 • 469 citations

Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.

1993 • 399 citations

Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization.

1993 • 344 citations

Growth factors in the regulation of pericellular proteolysis: a review.

1989 • 342 citations

Pathobiology of pulmonary fibrosis

1990 • 326 citations

Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome.

1989 • 325 citations

The role of intraalveolar fibrosis in the process of pulmonary structural remodeling in patients with diffuse alveolar damage.

1987 • 297 citations

Depressed Bronchoalveolar Urokinase Activity in Patients with Adult Respiratory Distress Syndrome

1990 • 271 citations

Development of venous occlusions in mice transgenic for the plasminogen activator inhibitor-1 gene

1990 • 268 citations

Complete Deficiency of Plasminogen-Activator Inhibitor Type 1 Due to a Frame-Shift Mutation

1992 • 267 citations

Intraluminal fibrosis in interstitial lung disorders.

1986 • 249 citations

Type 1 plasminogen activator inhibitor

1990 • 244 citations

Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane

1982 • 226 citations

Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B.

1986 • 221 citations

Alveolitis and Collapse in the Pathogenesis of Pulmonary Fibrosis

1989 • 178 citations

The Fibrinolytic Enzyme System and Its Role in the Etiology of Thromboembolic Disease

1990 • 165 citations

The Effects of the Nude(nu/nu)Mutation on Bleomycin-induced Pulmonary Fibrosis

1983 • 145 citations

Abnormalities in pathways of alveolar fibrin turnover among patients with interstitial lung disease.

1986 • 139 citations

Type 1 plasminogen activator inhibitor

1990 • 113 citations

Disorganization of Cultured Vascular Endothelial Cell Monolayers by Fibrinogen Fragment D

1985 • 111 citations

The development of bleomycin-induced pulmonary fibrosis in neutrophil-depleted and complement-depleted rats.

1981 • 107 citations

Peptide-mediated inactivation of recombinant and platelet plasminogen activator inhibitor-1 in vitro.

1995 • 100 citations

Endogenous receptor-bound urokinase mediates tissue invasion of human monocytes.

1989 • 96 citations

Bleomycin-induced pulmonary fibrosis. Effects of steroid on lung collagen metabolism.

1981 • 95 citations

Plasmin degradation of cartilage proteoglycan

1984 • 89 citations

The Intensity of Chronic Lung Inflammation and Fibrosis after Bleomycin Is Directly Related to the Severity of Acute Injury

1988 • 80 citations

Local abnormalities of coagulation and fibrinolytic pathways that promote alveolar fibrin deposition in the lungs of baboons with diffuse alveolar damage.

1989 • 79 citations

Co-operation between plasmin and elastase in elastin degradation by intact murine macrophages

1984 • 72 citations

Procoagulant and Plasminogen Activator Activities of Bronchoalveolar Fluid in Patients with Pulmonary Sarcoidosis

1988 • 70 citations

Intra-alveolar fibrosis of idiopathic bronchiolitis obliterans-organizing pneumonia. Cell-matrix patterns.

1990 • 68 citations

Abnormalities of pathways of fibrin turnover in lung lavage of rats with oleic acid and bleomycin-induced lung injury support alveolar fibrin deposition.

1989 • 61 citations

Bronchoalveolar Lavage Procoagulant Activity in Bleomycin-Induced Lung Injury in Marmosets: Characterization and Relationship to Fibrin Deposition and Fibrosis

1987 • 55 citations

Rat alveolar epithelial cells concomitantly express plasminogen activator inhibitor-1 and urokinase

1991 • 45 citations

Disordered Pathways of Fibrin Turnover in Lung Lavage of Premature Infants with Respiratory Distress Syndrome

1992 • 42 citations

Partial reversal of established bleomycin-induced pulmonary fibrosis by rh-urokinase in a rat model.

1994 • 39 citations

Fibrinolytic activity in bronchoalveolar lavage of baboons with diffuse alveolar damage

1992 • 30 citations

Alveolar Epithelial Cells Express Both Plasminogen Activator and Tissue Factor

1991 • 15 citations

Cited By (0)

No citing papers found in database

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress… (1996) – Journal of Clinical Investigation | Metascience Observatory Explorer