Addressing the Tertiary Structure of Human Parathyroid Hormone-(1–34)

Molecular dynamics with coupling to an external bath

1984 • 27,984 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

Settle: An analytical version of the SHAKE and RATTLE algorithm for rigid water models

1992 • 6,741 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

Investigation of exchange processes by two-dimensional NMR spectroscopy

1979 • 4,720 citations

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy

1983 • 2,638 citations

A two-dimensional nuclear overhauser experiment with pure absorption phase in four quadrants

1982 • 2,567 citations

Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering

1983 • 2,327 citations

The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

1992 • 2,028 citations

Structure determination of a tetrasaccharide: transient nuclear Overhauser effects in the rotating frame

1984 • 1,650 citations

Intermolecular Forces

1981 • 836 citations

Two-dimensional chemical exchange and cross-relaxation spectroscopy of coupled nuclear spins

1981 • 754 citations

Accurate simulation of protein dynamics in solution.

1988 • 442 citations

An evaluation of computational strategies for use in the determination of protein structure from distance constraints obtained by nuclear magnetic resonance

1991 • 426 citations

Membrane lipid phase as catalyst for peptide-receptor interactions.

1986 • 375 citations

Synthesis of a Biologically Active N-Terminal Tetratriacontapeptide of Parathyroid Hormone

1971 • 221 citations

Protein structures from NMR

1988 • 212 citations

The relationship between chemical shift and secondary structure in proteins

1990 • 171 citations

Parathyroid Hormone: Chemistry, Biosynthesis, and Mode of Action

1982 • 161 citations

fd Coat Protein Structure in Membrane Environments

1993 • 155 citations

The Use of Dodecylphosphocholine Micelles in Solution NMR

1995 • 149 citations

Peptide flexibility and calculations of an ensemble of molecules

1994 • 120 citations

Location and orientation relative to the micelle surface for glucagon in mixed micelles with dodecylphosphocholine EPR and NMR studies

1981 • 117 citations

Peptide–membrane interactions and a new principle in quantitative structure–activity relationships

1991 • 102 citations

New evidence for a membrane-bound pathway in hormone receptor binding

1993 • 96 citations

Location of M13 Coat Protein in Sodium Dodecyl Sulfate Micelles As Determined by NMR

1994 • 96 citations

Investigation of the solution structure of the human parathyroid hormone fragment (1-34) by proton NMR spectroscopy, distance geometry, and molecular dynamics calculations

1991 • 83 citations

Combined Approach of NMR and Molecular Dynamics within a biphasic Membrane Mimetic: Conformation and Orientation of the Bradykinin Antagonist Hoe 140

1994 • 81 citations

Direct mapping of an agonist-binding domain within the parathyroid hormone/parathyroid hormone-related protein receptor by photoaffinity crosslinking

1997 • 81 citations

Analogues of parathyroid hormone modified at positions 3 and 6. Effects on receptor binding and activation of adenylyl cyclase in kidney and bone

1991 • 75 citations

Interactions between hydrophobic side chains within α‐helices

1995 • 73 citations

Structure of Human Parathyroid Hormone 1–37 in Solution

1995 • 69 citations

NMR study of a 34‐residue N‐terminal fragment of the parathyroid‐hormone‐related protein secreted during humoral hypercalcemia of malignancy

1989 • 65 citations

[25] Structure-function analysis of proteins through the design, synthesis, and study of peptide models

1987 • 64 citations

NMR solution structure of human parathyroid hormone(1-34)

1993 • 63 citations

The Structure Of Human Parathyroid Hormone From a Study of Fragments in Solution Using 1H NMR Spectroscopy and Its Biological Implications

1994 • 62 citations

Parathyroid Hormone (PTH)-PTH-related Peptide Hybrid Peptides Reveal Functional Interactions between the 1–14 and 15–34 Domains of the Ligand

1995 • 62 citations

Inositol 1-,4-,5-trisphosphate-dependent Ca2+ signaling by the recombinant human PTH/PTHrP receptor stably expressed in a human kidney cell line

1996 • 60 citations

Improved molecular dynamics simulations for the determination of peptide structures

1993 • 52 citations

Coupling constants as restraints in ensemble distance driven dynamics

1994 • 47 citations

Structure of human parathyroid hormone(1-34) in the presence of solvents and micelles

1993 • 46 citations

Solution Structure of Parathyroid Hormone Related Protein (Residues 1–34) Containing an Ala Substituted for an Ile in Position 15 (PTHrP[Ala15]-(1–34))

1997 • 45 citations

Coupling constants and hydrogen bonds as experimental restraints in a distance geometry refinement protocol *

1994 • 44 citations

Structure of Cobra Cardiotoxin CTXI as Derived from Nuclear Magnetic Resonance Spectroscopy and Distance Geometry Calculations

1994 • 38 citations

Conformational consequences of i, i + 3 cystine linkages: nucleation for α‐helicity?

1997 • 35 citations

Conformational Studies of Mono- and Bicyclic Parathyroid Hormone-Related Protein-Derived Agonists

1997 • 33 citations

Mono- and Bicyclic Analogs of Parathyroid Hormone-Related Protein. 1. Synthesis and Biological Studies

1997 • 32 citations

Threonine⁶-Bradykinin: Structural Characterization in the Presence of Micelles by Nuclear Magnetic Resonance and Distance Geometry

1997 • 31 citations

Conformations of bombolitins I and III aqueous solutions: circular dichroism, proton NMR, and computer simulation studies

1990 • 29 citations

How do peptides interact with lipid membranes and how does this affect their biological activity?

1992 • 26 citations

Two‐dimensional ¹H‐NMR study of the 1–34 fragment of human parathyroid hormone

1989 • 24 citations

Conformational Studies of RS-66271, an Analog of Parathyroid Hormone-Related Protein with Pronounced Bone Anabolic Activity

1997 • 24 citations

Conformational studies of lipid-bound polypeptides by elucidation of proton-proton cross-relaxation networks

1980 • 23 citations

Stabilized NMR structure of the hypercalcemia of malignancy peptide PTHrP[Ala-26](1–34) amide

1994 • 21 citations

Interaction with model membrane systems induces secondary structure in amino‐terminal fragments of parathyroid hormone related protein

1994 • 20 citations

Nuclear magnetic resonance chemical shift: comparison of estimated secondary structures in peptides by nuclear magnetic resonance and circular dichroism

1996 • 15 citations