Conformational Studies of Mono- and Bicyclic Parathyroid Hormone-Related Protein-Derived Agonists

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

Computed circular dichroism spectra for the evaluation of protein conformation

1969 • 3,654 citations

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering

1983 • 2,327 citations

Clean TOCSY for proton spin system identification in macromolecules

1988 • 1,128 citations

Helix geometry in proteins

1988 • 1,042 citations

Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonance

1983 • 1,012 citations

Two-dimensional chemical exchange and cross-relaxation spectroscopy of coupled nuclear spins

1981 • 754 citations

Distance geometry and molecular conformation

1989 • 727 citations

An evaluation of computational strategies for use in the determination of protein structure from distance constraints obtained by nuclear magnetic resonance

1991 • 426 citations

Multiple quantum spin-echo spectroscopy

1980 • 390 citations

Rapid-pulsing artifacts in double-quantum-filtered COSY

1990 • 281 citations

Protein structures from NMR

1988 • 212 citations

Molecular dynamics simulation of galanin in aqueous and nonaqueous solution

1992 • 140 citations

Production of parathyroid hormone-like peptide in a human osteosarcoma cell line: stimulation by phorbol esters and epidermal growth factor

1989 • 118 citations

The sampling properties of some distance geometry algorithms applied to unconstrained polypeptide chains: A study of 1830 independently computed conformations

1990 • 114 citations

Cyclic parathyroid hormone-related protein antagonists: lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization

1991 • 104 citations

The design of metabolically-stable peptide analogs

1985 • 97 citations

Investigation of the solution structure of the human parathyroid hormone fragment (1-34) by proton NMR spectroscopy, distance geometry, and molecular dynamics calculations

1991 • 83 citations

Lactam bridge stabilization of α‐helical peptides: Ring size, orientation and positional effects

1995 • 77 citations

Modifications of position 12 in a parathyroid hormone and parathyroid hormone-related protein: toward the design of highly potent antagonists

1990 • 73 citations

Structure of Human Parathyroid Hormone 1–37 in Solution

1995 • 69 citations

Parathyroid hormone-related protein a peptide of diverse physiologic functions

1993 • 68 citations

NMR study of a 34‐residue N‐terminal fragment of the parathyroid‐hormone‐related protein secreted during humoral hypercalcemia of malignancy

1989 • 65 citations

Structural and Conformational Requirements for Human Calcitonin Activity: Design, Synthesis, and Study of Lactam-Bridged Analogs

1995 • 63 citations

The Structure Of Human Parathyroid Hormone From a Study of Fragments in Solution Using 1H NMR Spectroscopy and Its Biological Implications

1994 • 62 citations

Structural elements of human parathyroid hormone and their possible relation to biological activities

1992 • 59 citations

Parathyroid hormone-like peptide: Molecular characterization and biological properties

1989 • 47 citations

Coupling constants and hydrogen bonds as experimental restraints in a distance geometry refinement protocol *

1994 • 44 citations

Solution Structure and Adenylyl Cyclase Stimulating Activities of C-Terminal Truncated Human Parathyroid Hormone Analogs

1995 • 42 citations

Mono- and Bicyclic Analogs of Parathyroid Hormone-Related Protein. 1. Synthesis and Biological Studies

1997 • 32 citations

Mono- and Bicyclic Analogs of Parathyroid Hormone-Related Protein. 2. Conformational Analysis of Antagonists by CD, NMR, and Distance Geometry Calculations

1997 • 28 citations

NMR solution structure of the [Ala²⁶]parathyroid‐hormone‐related protein(1 – 34) expressed in humoral hypercalcemia of malignancy

1993 • 24 citations

Interaction with model membrane systems induces secondary structure in amino‐terminal fragments of parathyroid hormone related protein

1994 • 20 citations

Circular dichroism (CD) studies of antagonists derived from parathyroid hormone‐related protein

1993 • 18 citations

FTIR spectroscopy study of PTHrP(1–34) involved in humoral hypercalcaemia of malignancy

1993 • 5 citations