Defective splicing induced by 4NQO in the hamster hprt gene

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation

1986 • 755 citations

Exon definition may facilitate splice site selection in RNAs with multiple exons.

1990 • 726 citations

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1991 • 708 citations

Alternative splicing caused by RNA secondary structure

1985 • 274 citations

HPRT: GENE STRUCTURE, EXPRESSION, AND MUTATION

1985 • 227 citations

Positive Control of Pre-mRNA Splicing in Vitro

1992 • 199 citations

Control of Alternative Splicing by the Differential Binding of U1 Small Nuclear Ribonucleoprotein Particle

1991 • 191 citations

Cell Cycle-Dependent Strand Bias for UV-Induced Mutations in the Transcribed Strand of Excision Repair-Proficient Human Fibroblasts but Not in Repair-Deficient Cells

1991 • 169 citations

Tissue-Specific Splicing in Vivo of the β-Tropomyosin Gene: Dependence on an RNA Secondary Structure

1991 • 156 citations

Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene

1992 • 150 citations

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency

1983 • 146 citations

Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene.

1990 • 128 citations

Cell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cells.

1991 • 107 citations

Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene

1991 • 100 citations

Analysis of Mutations Occurring at the Human hprt Locus

1993 • 84 citations

Spectrum of spontaneously occurring mutations in the hprt gene of V79 Chinese hamster cells

1992 • 82 citations

DNA sequence analysis of in vivo hprt mutation in human T lymphocytes

1990 • 81 citations

A native RNA secondary structure controls alternative splice-site selection and generates two human growth hormone isoforms.

1992 • 80 citations

Kinds and location of mutations induced by (±)-7β,8α- dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts

1991 • 78 citations

Splicing Mutants and Their Second-Site Suppressors at the Dihydrofolate Reductase Locus in Chinese Hamster Ovary Cells

1993 • 77 citations

Adducts from in vivo action of the carcinogen 4-hydroxyaminoquinoline 1-oxide in rats and from in vitro reaction of 4-acetoxyaminoquinoline 1-oxide with DNA and polynucleotides.

1985 • 69 citations

Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells

1991 • 60 citations

Splicing mutants and their second-site suppressors at the dihydrofolate reductase locus in Chinese hamster ovary cells.

1993 • 56 citations

Molecular analysis of mutations affecting hprt mRNA splicing in human T‐lymphocytes in vivo

1992 • 51 citations

Strand specificity for mutations induced by (+)-anti BPDE in the hprt gene in human T-lymphocytes

1992 • 48 citations

Site specificity of N-methyl-N-nitrosourea-induced transition mutations in the hprt gene

1991 • 40 citations

Mutations causing defective splicing in the human hprt gene

1992 • 40 citations

Molecular analysis of ethylene oxide-induced mutations at the HPRT locus in human diploid fibroblasts

1993 • 38 citations

UV-induced hprt mutations in a UV-sensitive hamster cell line from complementation group 3 are biased towards the transcribed strand

1992 • 33 citations

DNA sequence analysis of 1-nitrosopyrene-induced mutations in the hprt gene of Chinese hamster ovary cells

1992 • 22 citations

Analysis of 4-nitroquinoline-1-oxide induced mutations at the hprt locus in mammalian cells: possible involvement of preferential DNA repair

1994 • 20 citations