Strain Amplification in the Bone Mechanosensory System

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Regulation of bone formation by applied dynamic loads.

1984 • 1,533 citations

Principles of Bone Biology

1997 • 1,367 citations

A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses

1994 • 1,229 citations

Reductions in Arterial Diameter Produced by Chronic Decreases in Blood Flow Are Endothelium-Dependent

1986 • 1,106 citations

Sensitivity of osteocytes to biomechanical stress in vitro

1995 • 768 citations

Integrins as mechanochemical transducers

1991 • 684 citations

Osteoregulatory nature of mechanical stimuli: Function as a determinant for adaptive remodeling in bone

1987 • 500 citations

Candidates for the Mechanosensory System in Bone

1991 • 462 citations

Morphological evidence of gap junctions between bone cells

1981 • 454 citations

Pulsating Fluid Flow Increases Nitric Oxide (NO) Synthesis by Osteocytes but Not Periosteal Fibroblasts - Correlation with Prostaglandin Upregulation

1995 • 418 citations

Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production

1990 • 343 citations

Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling?

1995 • 332 citations

A case for bone canaliculi as the anatomical site of strain generated potentials

1995 • 302 citations

Adaptive regulation of wall shear stress optimizing vascular tree function

1984 • 266 citations

Effect of flow on prostaglandin E2 and inositol trisphosphate levels in osteoblasts

1991 • 257 citations

Integrin expression in human bone

1993 • 256 citations

Real-time calcium response of cultured bone cells to fluid flow.

1995 • 229 citations

Vasoconstriction and increased flow: two principal mechanisms of shear stress-dependent endothelial autacoid release

1993 • 221 citations

Involvement of different ion channels in osteoblasts' and osteocytes' early responses to mechanical strain

1996 • 188 citations

Adaptive regulation of wall shear stress optimizing vascular tree function

1984 • 178 citations

Voltage‐activated and stretch‐activated Ba²⁺ conducting channels in an osteoblast‐like cell line (UMR 106)

1989 • 149 citations

Osteopontin and the Bone Remodeling Sequence

1995 • 119 citations

Effects of fluid shear stress on bone cells

1994 • 65 citations

Mechanotransduction in Bone

1998 • 62 citations

Phospholipase C: A Putative Mechanotransducer for Endothelial Cell Response to Acute Hemodynamic Changes

1993 • 58 citations

On the calculation of bone pore water pressure due to mechanical loading

1998 • 55 citations

Electrical signal transmission and gap junction regulation in a bone cell network: A cable model for an osteon

1997 • 43 citations

Electrical Signal Transmission in a Bone Cell Network: The Influence of a Discrete Gap Junction

1998 • 25 citations