Progesterone Receptor Membrane Component-1 (PGRMC1) Is the Mediator of Progesterone’s Antiapoptotic Action in Spontaneously Immortalized Granulosa Cells As Revealed by PGRMC1 Small Interfering Ribonucleic Acid Treatment and Functional Analysis of PGRMC1 Mutations

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes

2003 • 787 citations

Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor

2003 • 697 citations

Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases

2000 • 527 citations

Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells

2005 • 460 citations

Progesterone receptor membrane component 1: An integrative review

2007 • 347 citations

Transient Expression of Progesterone Receptor Messenger RNA in Ovarian Granuiosa Cells after the Preovulatory Luteinizing Hormone Surge

1991 • 335 citations

Hormonal regulation, localization, and functional activity of the progesterone receptor in granulosa cells of rat preovulatory follicles.

1993 • 289 citations

Purification and Partial Sequencing of High‐Affinity Progesterone‐Binding Site(s) from Porcine Liver Membranes

1996 • 276 citations

Heme as key regulator of major mammalian cellular functions: Molecular, cellular, and pharmacological aspects

2006 • 248 citations

Dap1/PGRMC1 Binds and Regulates Cytochrome P450 Enzymes

2007 • 226 citations

Progesterone Membrane Receptor Component 1 Expression in the Immature Rat Ovary and Its Role in Mediating Progesterone’s Antiapoptotic Action

2006 • 216 citations

Multiplicity of Progesterone's Actions and Receptors in the Mammalian Ovary1

2006 • 195 citations

Regulation of the progesterone receptor gene by gonadotropins and cyclic adenosine 3',5'-monophosphate in rat granulosa cells.

1994 • 138 citations

Molecular identification of adrenal inner zone antigen as a heme‐binding protein

2005 • 96 citations

Non-genomic progesterone receptors in the mammalian ovary: some unresolved issues

2003 • 92 citations

Expression of Progesterone Receptor (PR) A and B Isoforms in Mouse Granulosa Cells: Stage-Dependent PR-Mediated Regulation of Apoptosis and Cell Proliferation1

2003 • 92 citations

Basic Fibroblast Growth Factor Inhibits Apoptosis of Spontaneously Immortalized Granulosa Cells by Regulating Intracellular Free Calcium Levels through a Protein Kinase Cδ-Dependent Pathway**This work was supported by NIH Grant HD-33467.

2000 • 85 citations

Does the rat corpus luteum express the progesterone receptor gene?

1995 • 85 citations

A contemporary understanding of progesterone receptor function

2004 • 81 citations

Overexpression of the Cytochrome P450 Activator Hpr6 (Heme-1 Domain Protein/Human Progesterone Receptor) in Tumors

2005 • 81 citations

Expression and Function of PAIRBP1 Within Gonadotropin-Primed Immature Rat Ovaries: PAIRBP1 Regulation of Granulosa and Luteal Cell Viability1

2005 • 80 citations

Hpr6.6 protein mediates cell death from oxidative damage in MCF‐7 human breast cancer cells

2003 • 77 citations

Progesterone ”Receptor“ in Rat Ovary*

1979 • 75 citations

Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells

2001 • 74 citations

Progesterone Receptor-Mediated Inhibition of Apoptosis in Granulosa Cells Isolated from Rats Treated with Human Chorionic Gonadotropin1

2000 • 72 citations

E-Cadherin-Mediated Cell Contact Prevents Apoptosis of Spontaneously Immortalized Granulosa Cells by Regulating Akt Kinase Activity1

2001 • 72 citations

Rat ovarian granulosa cell culture: a model system for the study of cell-cell communication during multistep transformation.

1991 • 71 citations

Characterization of a Putative Membrane Receptor for Progesterone in Rat Granulosa Cells1

2001 • 65 citations

Hpr6 (Heme-1 Domain Protein) Regulates the Susceptibility of Cancer Cells to Chemotherapeutic Drugs

2005 • 64 citations

Non-Genomic Actions of Progesterone in the Normal and Neoplastic Mammalian Ovary

2007 • 64 citations

Binding of the anti-progestin ru-486 to rat ovary steroid receptors

1983 • 61 citations

Progesterone Regulates Granulosa Cell Viability Through a Protein Kinase G-Dependent Mechanism That May Involve 14-3-3σ1

2004 • 60 citations

Membrane-Initiated Events Account for Progesterone's Ability to Regulate Intracellular Free Calcium Levels and Inhibit Rat Granulosa Cell Mitosis1

2002 • 58 citations

Spectroscopic and Biochemical Characterization of Heme Binding to Yeast Dap1p and Mouse PGRMC1p

2005 • 58 citations

Classic and Non-classic Progesterone Receptors are both Expressed in Human Spermatozoa

2005 • 58 citations

Involvement of an Unnamed Protein, RDA288, in the Mechanism through which Progesterone Mediates Its Antiapoptotic Action in Spontaneously Immortalized Granulosa Cells

2004 • 56 citations

Characterization of high affinity progesterone-binding membrane proteins by an anti-peptide antiserum

1998 • 51 citations

Changes in inhibin activity, and progesterone, oestrogen and androstenedione concentrations, in rat follicular fluid throughout the oestrous cycle

1983 • 47 citations

Porcine spermatozoa contain more than one membrane progesterone receptor

2004 • 47 citations

Progesterone as a regulator of granulosa cell viability

2003 • 45 citations

Progesterone-Receptor Antagonists and Statins Decrease De Novo Cholesterol Synthesis and Increase Apoptosis in Rat and Human Periovulatory Granulosa Cells In Vitro1

2004 • 45 citations

Progesterone receptor in the rat ovary: Further characterization and localization in the granulosa cell

1979 • 41 citations

Chemical modification and structural analysis of the progesterone membrane binding protein from porcine liver membranes.

2001 • 27 citations

Characterization of cytoplasmic progesterone receptors in rat granulosa cells. Evidence for nuclear translocation

1981 • 26 citations

Rapid actions of progesterone on granulosa cells

2004 • 19 citations