Molecular and cellular markers for metastatic prostate cancer

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

ras oncogenes in human cancer: a review.

1989 • 5,116 citations

ras GENES

1987 • 3,818 citations

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1991 • 1,686 citations

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.

1991 • 1,592 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Cancer statistics, 1991

1991 • 625 citations

Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer.

1992 • 612 citations

Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles.

1991 • 440 citations

Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma

1991 • 286 citations

Expression ofrasOncogene p21 in Prostate Cancer

1986 • 269 citations

Clinical Evidence for and Implications of the Multistep Development of Prostate Cancer

1990 • 256 citations

NATURAL HISTORY OF LOCALISED PROSTATIC CANCER

1989 • 255 citations

NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice.

1985 • 240 citations

Recurrent Cerebral Ischæmia

1964 • 209 citations

ras gene mutations in human prostate cancer.

1990 • 202 citations

Stage D1 Prostatic Adenocarcinoma: Significance of Nuclear DNA Ploidy Patterns Studied by Flow Cytometry

1988 • 178 citations

Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell.

1985 • 175 citations

Decreased expression of E-cadherin in the progression of rat prostatic cancer.

1992 • 173 citations

Frequency and pattern of karyotypic abnormalities in human prostate cancer.

1990 • 172 citations

Genetic instability coupled to clonal selection as a mechanism for tumor progression in the Dunning R-3327 rat prostatic adenocarcinoma system.

1982 • 171 citations

Chromosome study of five cancers of the prostate

1985 • 152 citations

Activated ras alleles in human carcinoma of the prostate are rare.

1991 • 150 citations

Systematic Prostatic Biopsies in 100 Men with No Suspicion of Cancer on Digital Rectal Examination

1991 • 139 citations

Relationship between DNA ploidy, glandular differentiation, and tumor spread in human prostate cancer.

1985 • 136 citations

Localization of metastasis suppressor gene(s) for prostatic cancer to the short arm of human chromosome 11.

1992 • 130 citations

Stage B Prostate Adenocarcinoma

1990 • 116 citations

Non-hormone chemotherapy for prostate cancer: principles of treatment and application to the testing of new drugs.

1988 • 111 citations

Stage C Prostatic Adenocarcinoma: Flow Cytometric Nuclear DNA Ploidy Analysis

1989 • 107 citations

Stimulation of human prostatic carcinoma tumor growth in athymic mice and control of migration in culture by extracellular matrix

1992 • 96 citations

Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen B (CTRB) with the help of two overlapping deletions on the long arm of chromosome 16

1989 • 93 citations

Early cell motility changes associated with an increase in metastatic ability in rat prostatic cancer cells transfected with the v-Harvey-ras oncogene.

1988 • 75 citations

A Multidisciplinary Analysis of Controversies in the Management of Prostate Cancer

1988 • 74 citations

Genetic factors and suppression of metastatic ability of prostatic cancer.

1991 • 73 citations

Expression of a Transfected v-Harvey- Ras Oncogene in a Dunning Rat Prostate Adenocarcinoma and the Development of High Metastatic Ability

1988 • 59 citations

Nonrandom involvement of chromosome 4 in the progression of rat prostatic cancer

1988 • 56 citations

The Prognostic Value of Modal Deoxyribonucleic Acid in Low Grade, Low Stage Untreated Prostate Cancer

1990 • 55 citations

The Prognostic Value of DNA Ploidy Combined with Histologic Substaging for Incidental Carcinoma of the Prostate Gland

1988 • 55 citations

Prostate Cancer: The Magnitude of the Problem in the United States

1988 • 50 citations

Evaluation of Tumor Progression by Repeated Fine Needle Biopsies in Prostate Adenocarcinoma: Modal Deoxyribonucleic Acid Value and Cytological Differentiation

1990 • 49 citations

Chromosomal changes associated with progression of the Dunning R-3327 rat prostatic adenocarcinoma system.

1982 • 45 citations

Down modulation of fibronectin messenger RNA in metastasizing rat prostatic cancer cells revealed by differential hybridization analysis.

1988 • 44 citations

Oncogenes and metastatic progression.

1989 • 43 citations

Histochemical examination of expression of ras p21 protein and R 1881-binding protein in human prostatic cancers

1990 • 35 citations

H‐ras expression, genetic instability, and acquisition of metastatic ability by rat prostatic cancer cells following v‐H‐ras oncogene transfection

1991 • 27 citations

Expression of ras proto‐oncogenes in the dunning R3327 rat prostatic adenocarcinoma system

1988 • 21 citations

Oncogene expression in prostate cancer

1991 • 17 citations

Cooperation of oncogenes in the multistep transformation of established fibroblasts in culture.

1988 • 11 citations