The importance of being unfolded

From Levinthal to pathways to funnels

1997 • 2,277 citations

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

1997 • 1,041 citations

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity.

1996 • 562 citations

The concept of a random coil: Residual structure in peptides and denatured proteins

1996 • 322 citations

Comparison of the Backbone Dynamics of a Folded and an Unfolded SH3 Domain Existing in Equilibrium in Aqueous Buffer

1995 • 299 citations

The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, σ28

1997 • 193 citations

Structural Characterization of Folded and Unfolded States of an SH3 Domain in Equilibrium in Aqueous Buffer

1995 • 167 citations

The Bacterial Flagellar Motor

1994 • 117 citations

Conformational Changes in the Fibronectin Binding MSCRAMMs Are Induced by Ligand Binding

1996 • 100 citations

The Structure, Stability, and Folding Process of Amyloidogenic Mutant Human Lysozyme

1996 • 87 citations